US4145408A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Controlled release article
Assignee: Procter and Gamble Co
•
Filing: 1977-10-31
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Granted: 1979-03-20
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Expires: 1997-10-31
Abstract
Abstract Controlled release articles which regulate the concentration of a surfactant compound at a useful level in an environment external to said articles are provided. The articles are especially adapted for use in or on the bodies of animals, including humans, to provide controlled release of surfactants having biological activity, for example, non-hormonal contraceptives.
Inventors
- 👤 Robert G. Laughlin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:14
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/009; A61K9/0012; A61K9/0034; A61K9/0036; A61K9/0092
Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
76 words
A controlled release article especially adapted to maintaining a useful concentration of a spermicidal surfactant compound in the vagina, comprising: (a) a solution consisting essentially of: (i) a micelle-forming nonionic spermicidal surfactant compound, and (ii) water, said solution having a concentration above the critical micelle concentration of the spermicidal surfactant compound, said solution being releasably enclosed in; (b) a stable, insoluble container, at least part of the wall of said container comprising a microporous non-cellulose membrane.
Claim 2
Dependent Claim
76 words
A controlled release article especially adapted to maintaining a useful concentration of a spermicidal surfactant compound in the vagina, comprising: (a) a solution consisting essentially of: (i) a micelle-forming nonionic spermicidal surfactant compound, and (ii) water, said solution having a concentration above the critical micelle concentration of the spermicidal surfactant compound, said solution being releasably enclosed in; (b) a stable, insoluble container, at least part of the wall of said container comprising a microporous non-cellulose membrane.
Claim 3
Dependent Claim
25 words
An article according to claim 1 wherein the spermicidal surfactant compound is characterized by a critical micelle concentration of at most about 1×10 -3 Molar.
Claim 4
Dependent Claim
37 words
An article according to claim 2 wherein the combination of spermicidal surfactant solution and membrane exhibits a monomer transport curve having a ratio of slopes S 2 /S 1 in the range of 0 to about 0.1.
Claim 5
Dependent Claim
17 words
An article according to claim 3 wherein the spermicidal surfactant has an R value greater than 1.
Claim 6
Dependent Claim
22 words
An article according to claim 1 wherein the spermicidal surfactant is a nonionic surfactant selected from ethylene oxide condensates of aliphatic alcohols.
Claim 7
Dependent Claim
16 words
An article according to claim 5 wherein the nonionic surfactant is C 10 EO 5 .
Claim 8
Dependent Claim
16 words
An article according to claim 5 wherein the nonionic surfactant is C 10 EO 6 .
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1982-03-19 | 1982-09-18 | 1983-03-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1986-03-19 | 1986-09-18 | 1987-03-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1990-03-19 | 1990-09-18 | 1991-03-20 | $7700.00 | Window Closed / Lapsed |