US4088448A
Expired / Lapsed
US
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Apparatus for sampling, mixing the sample with a reagent and making particularly optical analyses
Assignee: MIGRATA UK Ltd A UK Co
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Filing: 1976-09-16
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Granted: 1978-05-09
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Expires: 1996-09-16
Abstract
Abstract A cuvette for sampling with a cavity which is defined by two planar surfaces which are placed or can be placed at a predetermined distance from one another. A reagent is contained in the cavity in an amount which is exactly determined in relation to the volume of the cavity. The sample is drawn into the cavity preferably by capillary force and mixed with the reagent therein spontaneously or by vibration, whereupon optical analysis takes place directly through the two planar surfaces.
Inventors
- 👤 Jan E. Lilja
- 👤 Sven E. L. Nilsson
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 06:41
CPC Classifications
G; G01; G01N; G01N21/00; G01N21/01; G01N21/03; B; B01; B01F; B01F33/00; B01F33/45; B01F35/00; B01F35/71; B01F35/717; B01F35/7172; B01F35/7173; B01L; B01L3/00; B01L3/50; B01L3/502; B01L3/5027; G01N1/00; G01N1/28; B01F21/00; B01F2101/00; B01F2101/23; B01F23/00; B01F23/50; B01F23/56; B01F31/00; B01L2200/00; B01L2200/06; B01L2200/0642; B01L2200/16; B01L2300/00; B01L2300/06; B01L2300/0627; B01L2300/0654; B01L2300/08; B01L2300/0809; B01L2300/0825; B01L2300/0861; B01L2300/0864; B01L2300/087; B01L2400/00; B01L2400/04; B01L2400/0403; B01L2400/0406; B01L3/502715; G01N2021/0346
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
108 words
A cuvette for sampling a fluid, mixing the sample with a reagent, and directly making optical analyses of the sample mixed with the reagent, comprising a body member including two planar surfaces defining an optical path and placed at a predetermined distance from one another to determine the optical path length and to define at least one cavity having an inlet communicating the at least one cavity with the exterior of the body member, the at least one cavity having a predetermined fixed volume, the predetermined distance being effective to permit the sample to enter the cavity by capillary force; and a reagent coated on the cavity surface.
Claim 2
Dependent Claim
108 words
A cuvette for sampling a fluid, mixing the sample with a reagent, and directly making optical analyses of the sample mixed with the reagent, comprising a body member including two planar surfaces defining an optical path and placed at a predetermined distance from one another to determine the optical path length and to define at least one cavity having an inlet communicating the at least one cavity with the exterior of the body member, the at least one cavity having a predetermined fixed volume, the predetermined distance being effective to permit the sample to enter the cavity by capillary force; and a reagent coated on the cavity surface.
Claim 3
Dependent Claim
32 words
A cuvette as claimed in claim 1, wherein the reagent is in the form of a solid material deposited on the walls of the cavity by evaporation, freeze-drying, spraying or screen printing.
Claim 4
Dependent Claim
21 words
A cuvette as claimed in claim 1, wherein the reagent is in the form of a semi-solid material, particularly a gel.
Claim 5
Dependent Claim
39 words
A cuvette as claimed in claim 1, wherein the cuvette has a receiving space communicating with the at least one cavity and with the inlet and from which the at least one cavity withdraws the sample by capillary force.
Claim 6
Dependent Claim
30 words
A cuvette as claimed in claim 1, wherein said body member has a plurality of cavities arranged in parallel or in series, said cavities containing the same or different reagents.
Claim 7
Dependent Claim
31 words
A cuvette as claimed in claim 1, wherein said body member is adapted for mixing of the sample with the reagent by actuation from the outer side of the body member.
Claim 8
Dependent Claim
18 words
A cuvette as claimed in claim 6, wherein said body member is adapted for mixing actuation by vibration.
Claim 9
Dependent Claim
32 words
A cuvette as claimed in claim 1, wherein at least one of the walls defining the cavity of the body member is stepped with exactly determined height differences between the different steps.
Claim 10
Dependent Claim
20 words
A cuvette as claimed in claim 1, wherein the reagent or reagents are coated for regulation of the dissolution rate.
Claim 11
Dependent Claim
28 words
A cuvette as claimed in claim 1, wherein the at least one cavity is oriented with its longitudinal direction at right angles with the body member planar surfaces.
Claim 12
Dependent Claim
14 words
A cuvette as claimed in claim 1, made from transparent plastic material or glass.
Claim 13
Dependent Claim
139 words
A cuvette for sampling a fluid, mixing the sample with a reagent, and directly making optical analyses of the sample mixed with the reagent, comprising a body member including two flexible surfaces and means joining the two surfaces to define at least one cavity having an inlet communicating the at least one cavity with the exterior of the body member, the joining means separating the flexible surfaces by a dimension effective to permit the sample to enter the at least one cavity by capillary force, the two flexible surfaces being adapted to be placed at a predetermined distance from one another by actuation from the outer side of the body member to define an optical path having a predetermined optical path length and to provide a predetermined volume in the cavity; and a reagent coated on the cavity surface.
Claim 14
Dependent Claim
139 words
A cuvette for sampling a fluid, mixing the sample with a reagent, and directly making optical analyses of the sample mixed with the reagent, comprising a body member including two flexible surfaces and means joining the two surfaces to define at least one cavity having an inlet communicating the at least one cavity with the exterior of the body member, the joining means separating the flexible surfaces by a dimension effective to permit the sample to enter the at least one cavity by capillary force, the two flexible surfaces being adapted to be placed at a predetermined distance from one another by actuation from the outer side of the body member to define an optical path having a predetermined optical path length and to provide a predetermined volume in the cavity; and a reagent coated on the cavity surface.
Claim 15
Dependent Claim
33 words
A cuvette as claimed in claim 12, further comprising a spacing element disposed in the cavity to determine the distance between the walls of the cavity upon actuation of said walls from outside.
Claim 16
Dependent Claim
16 words
A cuvette as claimed in claim 13, wherein the reagent is carried by the spacing element.
Claim 17
Dependent Claim
34 words
A cuvette as claimed in claim 13, wherein the spacing element is of ferromagnetic material to provide mixing of the sample and the reagent when the cuvette is placed in a variable magnetic field.
Claim 18
Dependent Claim
18 words
A cuvette as claimed in claim 12 further comprising a reagent in the cavity in the predetermined amount.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1981-05-08 | 1981-11-07 | 1982-05-09 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1985-05-08 | 1985-11-07 | 1986-05-09 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1989-05-08 | 1989-11-07 | 1990-05-09 | $7700.00 | Window Closed / Lapsed |