New oral form of medicament and a method for producing it

Claim 1

A therapeutically-useful and pharmacologically-acceptable oral depot medicament form comprising substantially uniformly-sized spheroidal medicament particals, each of which is provided with a dialysis membrane and has a diameter of between 0.1 and 2 millimeters, the dialysis membrane having a film-forming component which comprises (a) from 15 to 70 percent by weight of a cellulose ether, selected from the group consisting of methyl cellulose, ethyl cellulose and propyl cellulose, which is insoluble in the pH range of the gastrointestinal tract, which is not enzymatically degraded, which has an alkoxy-group content of from 43 to 50 percent by weight, and which has a viscosity of from about 7 to 100 centipoises in a 5 percent by weight toluene-ethanol mixture (80:20 parts by weight) at 25° C and (b) from 85 to 30 percent by weight of an organic-compound component which is substantially only soluble in the alkaline pH range of the intestinal tract, which contains from 5 to 40 percent by weight of free carboxyl groups, and which comprises at least one organic compound selected from the group consisting of palmitic acid, myristic acid and stearic acid.