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US3947566A Expired / Lapsed US ⏱️ 0.0 years remaining

Effervescent medicaments

Assignee: Phoenix Research Inc
•
Filing: 1974-01-04
•
Granted: 1976-03-30
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Expires: 1994-01-04
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Abstract

Abstract Medicament compositions exhibiting effervescence comprise a medicament and a liquefied gas distributed therethrough. The liquefied gas is present in the compositions at pressure and temperature conditions at which it would normally exist only in the gaseous state. As the liquefied gas separate from the compositions, effervescence occurs.

Inventors

  • 👤 Edward J. Sarna
  • 👤 Norman H. Ishler
  • 👤 Joseph Jellema

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 15:18
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/10; A61K9/12; A61K9/0002; A61K9/0007

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 188 words
An effervescing medicament composition confined under pressure in an aerosol dispensing container, said medicament composition consisting essentially of (a) a liquefied gas having a boiling point of from about -50°F. to about 80°F. and an aqueous or alcoholic phase (b) containing a medicament selected from the group consisting of a cough preparation, an analgesic and a stomach alkalizer and being substantially free of an agent capable of emulsifying the liquefied gas (a) in said phase (b), said phase (b) being substantially non-soluble with (a) and being dispersible with (a) with agitation thereof, liquefied gas (a) having a density greater than (b) and the quantity of (a) being at least about 5 percent by weight in excess of the quantity required to propel (b) from said container, said medicament composition being characterized by effervescence when said aerosol container is agitated whereupon (a) is dispersed in (b), and, while (a) and (b) are interdispersed, discharging contents of the container as a liquid stream into a vessel, some of the dispersed liquefied gas (a) remaining dispersed and entrained as a liquid in said liquid stream after the contents leave the container.
Claim 2
Dependent Claim 188 words
An effervescing medicament composition confined under pressure in an aerosol dispensing container, said medicament composition consisting essentially of (a) a liquefied gas having a boiling point of from about -50°F. to about 80°F. and an aqueous or alcoholic phase (b) containing a medicament selected from the group consisting of a cough preparation, an analgesic and a stomach alkalizer and being substantially free of an agent capable of emulsifying the liquefied gas (a) in said phase (b), said phase (b) being substantially non-soluble with (a) and being dispersible with (a) with agitation thereof, liquefied gas (a) having a density greater than (b) and the quantity of (a) being at least about 5 percent by weight in excess of the quantity required to propel (b) from said container, said medicament composition being characterized by effervescence when said aerosol container is agitated whereupon (a) is dispersed in (b), and, while (a) and (b) are interdispersed, discharging contents of the container as a liquid stream into a vessel, some of the dispersed liquefied gas (a) remaining dispersed and entrained as a liquid in said liquid stream after the contents leave the container.
Claim 3
Dependent Claim 13 words
The composition of claim 1 containing about 14 percent by weight of octafluorocyclobutane.
Claim 4
Dependent Claim 15 words
A composition of claim 1, wherein the container is at a temperature below about -50°F.
Claim 5
Dependent Claim 11 words
A composition of claim 1, wherein the vessel contains a liquid.
Claim 6
Dependent Claim 13 words
A composition of claim 1, wherein the liquefied gas is octafluorocyclobutane or monochloropentafluoroethane.
Claim 7
Dependent Claim 13 words
A composition of claim 1, wherein the aqueous phase is a cough preparation.
Claim 8
Dependent Claim 13 words
A composition of claim 1, wherein the aqueous phase is a stomach alkalizer.
Claim 9
Dependent Claim 12 words
A composition of claim 1 containing a mixture of said liquefied gases.

References Cited (Backward Citations)

US2655480A Cited
US2995521A Cited
US3092555A Cited
US3144386A Cited
US3282781A Cited
US3131153A Cited
US3304230A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-03-30 1979-09-29 1980-03-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-03-30 1983-09-29 1984-03-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-03-30 1987-09-29 1988-03-30 $7700.00 Window Closed / Lapsed

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