Patent US3941772A successfully refreshed from Google Patents.
← Back to Patent Explorer
US3941772A Expired / Lapsed US ⏱️ 0.0 years remaining

Azacycloalkane-2,2-diphosphonic acids

Assignee: Henkel AG and Co KGaA
•
Filing: 1974-08-20
•
Granted: 1976-03-02
•
Expires: 1994-08-20
📄 Original PDF 🌐 Google Patents 🔄 Sync Now

Abstract

Abstract Azacycloalkane-2,2-diphosphonic acids having the formula ##EQU1## wherein R is a member selected from the group consisting of hydrogen and alkyl having from 1 to 3 carbon atoms and n is an integer from 3 to 5; as well as their water-soluble salts. The azacycloalkane-2,2-diphosphonic acids are excellent sequestering agents especially for alkaline earth metal ions. They are stabilizers for percompounds and are useful in the delaying of the setting times for gypsum. In addition, the compound are useful in cosmetic preparations such as toothpastes and mouthwashes where they prevent formation of tartar and plaque and are useful in therapy in the treatment of diseases related to the abnormal deposition or dissolution of difficulty soluble calcium salts in the animal body.

Inventors

  • 👤 Walter Ploger
  • 👤 Manfred Schmidt-Dunker
  • 👤 Christian Gloxhuber

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 19:07
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/66; A61K31/675; A61K8/00; A61K8/18; A61K8/30; A61K8/55; A61Q; A61Q11/00; C; C02; C02F; C02F5/00; C02F5/08; C02F5/10; C02F5/14; C07; C07F; C07F9/00; C07F9/02; C07F9/28; C07F9/38; C07F9/3804; C07F9/3839; C07F9/3873; C07F9/547; C07F9/553; C07F9/5532; C07F9/572

Claims Analysis

Total Claims: 9
Claim 1
Independent Claim 51 words
An azacycloalkane-2,2-diphosphonic compound selected from the group consisting of (A) a compound of the formula ##EQU9## wherein R is selected from the group consisting of hydrogen and alkyl having 1 to 3 carbon atoms, and n is an integer from 3 to 5; and (B) a non-toxic, pharmacologically-acceptable water-soluble salt thereof.
Claim 2
Dependent Claim 51 words
An azacycloalkane-2,2-diphosphonic compound selected from the group consisting of (A) a compound of the formula ##EQU9## wherein R is selected from the group consisting of hydrogen and alkyl having 1 to 3 carbon atoms, and n is an integer from 3 to 5; and (B) a non-toxic, pharmacologically-acceptable water-soluble salt thereof.
Claim 3
Dependent Claim 27 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein R is selected from the group consisting of hydrogen and methyl and n is an integer from 3 to 5.
Claim 4
Dependent Claim 14 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein R is hydrogen and n is 3.
Claim 5
Dependent Claim 14 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein R is methyl and n is 3.
Claim 6
Dependent Claim 14 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein R is hydrogen and n is 4.
Claim 7
Dependent Claim 14 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein R is hydrogen and n is 5.
Claim 8
Dependent Claim 29 words
The azacycloalkane-2,2-diphosphonic compound of claim 1, wherein said non-toxic, pharmacologicallyacceptable water-soluble salt is a member selected from the group consisting of alkali metals, ammonium, lower alkanolammonium, zinc and magnesium.
Claim 9
Dependent Claim 24 words
The azacycloalkane-2,2-diphosphonic compound of claim 7, wherein said water-soluble salts are substantially neutral with a pH of 5 to 9 in an aqueous solution.

References Cited (Backward Citations)

US3846420A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1979-03-02 1979-09-01 1980-03-02 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1983-03-02 1983-09-01 1984-03-02 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1987-03-02 1987-09-01 1988-03-02 $7700.00 Window Closed / Lapsed

Assigned Categories & Tags

No categories assigned to this patent yet.

Assign Category Tag