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US3926797A Expired / Lapsed US ⏱️ 0.0 years remaining

Separation apparatus using ultrafiltration

Assignee: Gambro Industries SAS
•
Filing: 1972-03-15
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Granted: 1975-12-16
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Expires: 1992-03-15
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Abstract

Abstract Apparatus is provided for the purification of a liquid, especially blood, which comprises: A. AN ULTRAFILTRATION CELL AND AN ULTRAFILTRATION MEMBRANE DIVIDING SAID CELL INTO TWO COMPARTMENTS, AN INLET AND AN OUTLET FOR SAID FIRST COMPARTMENT FOR THE LIQUID TO BE TREATED AND AN OUTLET FOR THE ULTRAFILTERED LIQUID FOR SAID SECOND COMPARTMENT; B. MEANS FOR ESTABLISHING IN THE FIRST COMPARTMENT OF SAID ULTRAFILTRATION CELL A PRESSURE HIGHER THAN THAT PREVAILING IN THE SECOND COMPARTMENT OF THE CELL; AND C. A DIALYSER AND AN IONIC MEMBRANE SEPARATING SAID DIALYSER INTO TWO COMPARTMENTS, AN INLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET FROM THE SECOND COMPARTMENT OF THE ULTRAFILTRATION CELL AND AN OUTLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET OF THE FIRST COMPARTMENT OF THE ULTRAFILTRATION CELL, THE SECOND COMPARTMENT OF SAID DIALYSER BEING ITSELF EQUIPPED WITH AN INLET AND AN OUTLET.

Inventors

  • 👤 Claude Gigou
  • 👤 Jean-Pierre Quentin

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:28
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/34; A61M1/3472; A61M1/3479

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 157 words
APPARATUS FOR THE PURICATION OF A LIQUID, WHICH COMPRISES: A. AN UNTRAFLITRATION CELL AND AN ULTRAFILTRATION MEMBRANE, DIVIDING SAID CELL INTO TWO COMPARTMENTS, AN INLET AND AN OUTLET FOR SAID FIRST COMPARTMENT FOR THE LIQUID TO BE TREATED AND AN OUTLET FOR THE ULTRAFILTERED LIQUID FOR SAID SECOND COMPARTMENT; B. MEANS FOR EXTABILISHING IN THE FIRST COMPARTMENT OF SAID ULTRAFILTRATION CELL A PRESSURE HIGHER THAN THAT PREVAILING IN THE SECOND COMPARTMENT OF THE CELL; AND C. A DIALYSER AND AN IONIC MEMBRANE SEPARATING SAID DIALYSER INTO TWO COMPARTMENTS, AN ININLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET FROM THE SECOND COMPARTMENT OF THE ULTRAFILTRATION CELL AND AN OUTLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET OF THE FIRST COMPARTMENT OF THE ULTRAFILTRATION CELL, THE SECOND COMPARTMENT OF SAID DIALYSER BEING ITSELF EQUIPPED WITH AN INLET AND AN OUTLET, SAID IONIC MEMBRANE HAVING A SELECTIVE PERMEABILITY GREATER THAN 50% AND A UREA/NACL SELECTIVITY GREATER THAN 5.
Claim 2
Dependent Claim 157 words
APPARATUS FOR THE PURICATION OF A LIQUID, WHICH COMPRISES: A. AN UNTRAFLITRATION CELL AND AN ULTRAFILTRATION MEMBRANE, DIVIDING SAID CELL INTO TWO COMPARTMENTS, AN INLET AND AN OUTLET FOR SAID FIRST COMPARTMENT FOR THE LIQUID TO BE TREATED AND AN OUTLET FOR THE ULTRAFILTERED LIQUID FOR SAID SECOND COMPARTMENT; B. MEANS FOR EXTABILISHING IN THE FIRST COMPARTMENT OF SAID ULTRAFILTRATION CELL A PRESSURE HIGHER THAN THAT PREVAILING IN THE SECOND COMPARTMENT OF THE CELL; AND C. A DIALYSER AND AN IONIC MEMBRANE SEPARATING SAID DIALYSER INTO TWO COMPARTMENTS, AN ININLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET FROM THE SECOND COMPARTMENT OF THE ULTRAFILTRATION CELL AND AN OUTLET FOR SAID FIRST COMPARTMENT CONNECTED TO THE OUTLET OF THE FIRST COMPARTMENT OF THE ULTRAFILTRATION CELL, THE SECOND COMPARTMENT OF SAID DIALYSER BEING ITSELF EQUIPPED WITH AN INLET AND AN OUTLET, SAID IONIC MEMBRANE HAVING A SELECTIVE PERMEABILITY GREATER THAN 50% AND A UREA/NACL SELECTIVITY GREATER THAN 5.
Claim 3
Dependent Claim 24 words
Apparatus according to claim 1 in which the ionic membrane has a selective permeability greater than 70% and a urea/NaCl selectivity greater than 10.
Claim 4
Dependent Claim 33 words
Apparatus according to claim 1 in which the ionic membrane contains carboxylic, sulphonic, phosphonic or phosphinic acid groups or salified carboxylic, sulphonic, phosphonic or phosphinic acid groups, or sulphonium, phosphonium or ammonium groups.
Claim 5
Dependent Claim 30 words
Apparatus according to claim 1 in which a device for the removal of blood waste products is connected to the inlet and outlet from the second compartment of said dialyser.
Claim 6
Dependent Claim 18 words
Apparatus according to claim 4 in which the device is an activated charcoal or ion exchange resin column.
Claim 7
Dependent Claim 63 words
In a process for the continuous treatment of a blood ultrafiltrate the improvement which comprises passing the ultrafiltrate to a dialyser equipped with an ionic membrane, the second compartment of the dialyser being traversed by a purifying liquid with an osmotic pressure less than or equal to the osmotic pressure of the ultrafiltrate, and then reintroducing the resulting purified ultrafiltrate into the blood.
Claim 8
Dependent Claim 63 words
In a process for the continuous treatment of a blood ultrafiltrate the improvement which comprises passing the ultrafiltrate to a dialyser equipped with an ionic membrane, the second compartment of the dialyser being traversed by a purifying liquid with an osmotic pressure less than or equal to the osmotic pressure of the ultrafiltrate, and then reintroducing the resulting purified ultrafiltrate into the blood.
Claim 9
Dependent Claim 17 words
Process according to claim 6 in which the purifying liquid is water or an aqueous sugar solution.
Claim 10
Dependent Claim 162 words
Process according to claim 6 which is carried out in an apparatus which comprises: a. an ultrafiltration cell and an ultrafiltration membrane, dividing said cell into two compartments, an inlet and an outlet for said first compartment for the liquid to be treated and an outlet for the ultrafiltered liquid for said second compartment; b. means for establishing in the first compartment of said ultrafiltration cell a pressure higher than that prevailing in the second compartment of the cell; and c. a dialyser and an ionic membrane separating said dialyser into two compartments, an inlet for said first compartment connected to the outlet from the second compartment of the ultrafiltration cell and an outlet for said first compartment connected to the outlet of the first compartment of the ultrafiltration cell, the second compartment of said dialyser bEing itself equipped with an inlet and an outlet, said ionic membrane having a selective permeability greater than 50% and a urea/NaCl selectivity greater than 5.
Claim 11
Dependent Claim 85 words
Apparatus according to claim 1, in which the ionic membrane comprises a sulphonated styrene-divinylbenzene copolymer, a chloromethylated and quaternised styrene-divinylbenzene copolymer, a quaternised vinyl alcohol-vinylpyridine copolymer, a sulphated ethylene-vinyl alcohol copolymer, an ethylene-vinyl alkoxide copolymer in which the ether groups comprise amino-substituted polyethoxy groups, a quaternised acrylonitrile-vinylpyridine copolymer, a polyhydroxyether in which some, at least, of the hydroxy groups are etherified with amino-substituted polyethoxy groups, a sulphonated polyarylethersulphone, an amino-sulphonated styrene copolymer, an amino-methylated tetrafluoroethylene-styrene copolymer or an acrylonitrile-methallylsulphonic acid copolymer, or a salt thereof.

References Cited (Backward Citations)

US3004909A Cited
US3276598A Cited
US3579441A Cited
US3506126A Cited
US3617545A Cited
US3669880A Cited
US3727612A Cited
US3839200A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1978-12-15 1979-06-16 1979-12-16 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 1982-12-15 1983-06-16 1983-12-16 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 1986-12-15 1987-06-16 1987-12-16 $7700.00 Window Closed / Lapsed

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