Blood purification by dual filtration

Abstract

Abstract AN EXTRA-COPOREAL DEVICE EMPLOYING FILTRATION MEANS PERFORMS THE FUNCTIONS OF A NAUTAL KIDNEY IN THE FOLLOWING MANNER: ARTERIAL BLOOD IS FILTERED BY A HIGHLY SELECTIVE FILTRTION MEANS WHICH RETAINS MACROMOLECULAR WEIGHT BLOOD CONSTITUENTS SUCH AS BLOOD CELLS, FAT DROPLETS, HIGH MOLECULAR WEIGHT POLYPEPTIDES AND HIGH MOLECULAR WEIGHT LIPIDS, WHILE PERMITTING THE PASSAGE OF WATER AND LOW MOLECULAR WEIGHT SOLUTES. THE WATER AND SOLUTES ARE THEN PASSED THROUGH A SECOND FILTRATION MEANS OR COMBINATION OF FILTRATION AND ELECTRODIALYZIN MEANS WHICH PERMITS ONLY THE PASSAGE OF PURE WATER OR PURE WATER AND ELECTROLYTES. THE PURIFIED FILTRATE FROM THIS SECOND STAGE IS THEN COMBINED WITH A CONTROLLED AMOUNT OF MAKE-UP ELECTROLYTE SOLUTION, AND THIS COMBINED SOLUTION IS THEN MIXED WITH THE MACROMOLECULAR WEIGHT BLOOD CONSTITUENTS RETAINED BY THE FIRST FILTRATION MEANS TO FORM THE VENOUS RETURN.

Inventors

• 👤 Clinton E Brown

Bibliographic Details