Patent US3856919A successfully refreshed from Google Patents.
US3856919A
Expired / Lapsed
US
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Ophthalmic solution
Assignee: Alcon Vision LLC
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Filing: 1973-01-19
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Granted: 1974-12-24
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Expires: 1993-01-19
Abstract
Abstract An opthalmic solution is provided for treatment of ''''dre eye,'''' providing lubricating and cushioning effects for traumatized eyes, including trauma caused by the wearing of hard or gel-type contact lenses, and as a carrier for ophthalmic medicaments. The solution is an aqueous solution of polyethylene oxide, optionally polyethylene glycol, and other optional ingredients.
Inventors
- 👤 B Rankin
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:07
CPC Classifications
C; C08; C08L; C08L71/00; C08L71/02; A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0048
Claims Analysis
Total Claims: 17
Claim 1
Independent Claim
66 words
AN OPTHALMIC SOLUTION (COMPRISING) CONSISTING ESSENTIALLY OF AN AQUEOUS SOLUTION OF AN ETHYLENE OXIDE POLYMER, HAVING A MOLECULAR WEIGHT OF AT LEAST ABOUT 100,000, IN AN AMOUNT FROM ABOUT 0.05 TO 2.0 WEIGHT PERCENT SUFFICIENT TO PROVIDE A VISCOSITY OF FROM ABOUT 0 TO 30,000 CPS. AND UP TO ABOUT 5000 WEIGHT PERCENT, BASED ON THE WEIGHT OF THE ETHYLENE OXIDE POLYMER, OF AN OPTHALMIC MEDICAMENT.
Claim 2
Dependent Claim
66 words
AN OPTHALMIC SOLUTION (COMPRISING) CONSISTING ESSENTIALLY OF AN AQUEOUS SOLUTION OF AN ETHYLENE OXIDE POLYMER, HAVING A MOLECULAR WEIGHT OF AT LEAST ABOUT 100,000, IN AN AMOUNT FROM ABOUT 0.05 TO 2.0 WEIGHT PERCENT SUFFICIENT TO PROVIDE A VISCOSITY OF FROM ABOUT 0 TO 30,000 CPS. AND UP TO ABOUT 5000 WEIGHT PERCENT, BASED ON THE WEIGHT OF THE ETHYLENE OXIDE POLYMER, OF AN OPTHALMIC MEDICAMENT.
Claim 3
Dependent Claim
12 words
The composition of claim 1 wherein said opthalmic medicament is pilocarpine hydrochloride.
Claim 4
Dependent Claim
20 words
The composition of claim 1 wherein said aqueous solution further includes an effective amount of an eye compatible pH buffer.
Claim 5
Dependent Claim
11 words
The composition of claim 3 wherein the buffer is boric acid.
Claim 6
Dependent Claim
16 words
The composition of claim 3 wherein said buffer is a combination of monosodium and disodium phosphates.
Claim 7
Dependent Claim
34 words
The composition of claim 1 wherein said aqueous solution further includes a mechanical buffer selected from the group consisting of methyl cellulose, hydroxyethyl cellulose, hydroxypropyl cellulose, carboxymethyl cellulose, hydroxypropyl methyl cellulose and mixtures thereof.
Claim 8
Dependent Claim
23 words
The composition of claim 1 wherein said aqueous solution further includes up to about one percent by weight of an eye compatible biocide.
Claim 9
Dependent Claim
23 words
The composition of claim 1 wherein said aqueous solution further includes up to about 0.5% by weight of an eye compatible non-ionic surfactant.
Claim 10
Independent Claim
75 words
A method of treating the eye comprising adding thereto an opthalmic solution consisting essentially of an aqueous solution of an ethylene oxide polymer, having a molecular weight of at least about 100,000, in an amount from about 0.05 to 2.0 weight percent sufficient to provide a viscosity of from about 0 to 30, 000 cps. and up to about 500 weight percent, based on the weight of the ethylene oxide polymer, of an opthalmic medicament.
Claim 11
Independent Claim
75 words
A method of treating the eye comprising adding thereto an opthalmic solution consisting essentially of an aqueous solution of an ethylene oxide polymer, having a molecular weight of at least about 100,000, in an amount from about 0.05 to 2.0 weight percent sufficient to provide a viscosity of from about 0 to 30, 000 cps. and up to about 500 weight percent, based on the weight of the ethylene oxide polymer, of an opthalmic medicament.
Claim 12
Dependent Claim
70 words
An opthalmic solution consisting essentially of an aqueous solution of ethylene oxide having a molecular weight of at least about 100,000 in an amount from about .05 to 2.0 weight percent sufficient to provide a viscosity of from about 0 to 30,000 cps., an effective amount of an eye compatible buffer and up to 500 weight percent, based on this weight of the ethylene oxide polymer, of an opthalmic medicament.
Claim 13
Dependent Claim
70 words
An opthalmic solution consisting essentially of an aqueous solution of ethylene oxide having a molecular weight of at least about 100,000 in an amount from about .05 to 2.0 weight percent sufficient to provide a viscosity of from about 0 to 30,000 cps., an effective amount of an eye compatible buffer and up to 500 weight percent, based on this weight of the ethylene oxide polymer, of an opthalmic medicament.
Claim 14
Dependent Claim
16 words
The composition of claim 10 wherein said buffer is a combination of monosodium and disodium phosphates.
Claim 15
Dependent Claim
34 words
The composition of claim 10 wherein said aqueous solution further comprises a mechanical buffer selected from the group consisting of methyl cellulose, hydroxethyl cellulose, hydroxypropyl cellulose, carboxmethyl cellulose, hydroxypropyl methyl cellulose, and mixtures thereof.
Claim 16
Dependent Claim
23 words
The composition of claim 10 wherein said aqueous solution further comprises up to about 1 percent by weight of an eye compatible biocide.
Claim 17
Dependent Claim
24 words
The composition of claim 10 wherein said aqueous solution further includes up to about 0.5 percent by weight of an eye compatible non-ionic surfactant.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1977-12-23 | 1978-06-24 | 1978-12-24 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1981-12-23 | 1982-06-24 | 1982-12-24 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1985-12-23 | 1986-06-24 | 1986-12-24 | $7700.00 | Window Closed / Lapsed |