Patent US3767437A successfully refreshed from Google Patents.
US3767437A
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Phosthetic structures derived from collagen
Assignee: Avicon Inc
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Filing: 1971-10-20
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Granted: 1973-10-23
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Expires: 1991-10-20
Abstract
Abstract Artificial ivory and bone-like structures are formed from a complex partial salt of collagen with a metal hydroxide and with an ionizable acid such as calcium hydroxide and phosphoric acid. Calcium phosphate may be intimately mixed with the complex partial collagen salt before shaping into a desired configuration. Structural strength may be increased by incorporating fibers and other ions may be included to increase hardness.
Inventors
- 👤 M Cruz
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 20:09
CPC Classifications
C; C08; C08L; C08L89/00; C08L89/04; C08L89/06
Claims Analysis
Total Claims: 9
Claim 1
Independent Claim
13 words
The method of claim 1 wherein the polyvalent metal hydroxide is calcium hydroxide.
Claim 2
Dependent Claim
11 words
The method of claim 1 wherein the acid is phosphoric acid.
Claim 3
Dependent Claim
19 words
The method of claim 1 wherein the polyvalent metal hydroxide is calcium hydroxide and the acid is phosphoric acid.
Claim 4
Dependent Claim
24 words
The method of claim 1 wherein calcium phosphate is added to the complex partial salt of collagen before shaping into the predetermined structural configuration.
Claim 5
Dependent Claim
115 words
A unitary three-dimensional structure comprising a water-insoluble, complex partial salt of collagen containing a bound polyvalent metal ion, the polyvalent metal being one whose hydroxide is soluble in water at a pH between about 8 and 12, and containing a bound ionizable acid anion, the bound polyvalent metal ion replacing at least some of the free and available carboxyl groups of the collagen, the partial salt containing from about 0.15 to about 0.7 millimole of bound acid per gram of collagen based upon collagen containing about 0.78 millimole of available primary amino groups per gram of collagen, and the structure being further characterized by withstanding immersion in boiling water for at least about 6 hours.
Claim 6
Dependent Claim
16 words
A unitary three-dimensional structure as defined in claim 6 wherein the polyvalent metal ion is calcium.
Claim 7
Dependent Claim
16 words
A unitary three-dimensional structure as defined in claim 6 wherein the anion is the phosphate ion.
Claim 8
Dependent Claim
23 words
A unitary three-dimensional structure as defined in claim 6 wherein the polyvalent metal ion is calcium and the anion is the phosphate ion.
Claim 9
Dependent Claim
14 words
A unitary three-dimensional structure aS defined in claim 6 which includes intermixed calcium phosphate.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-10-22 | 1977-04-23 | 1977-10-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-10-22 | 1981-04-23 | 1981-10-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-10-22 | 1985-04-23 | 1985-10-23 | $7700.00 | Window Closed / Lapsed |