US3717502A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for providing anticoagulant surfaces onto articles
Assignee: Tokyo Medical and Dental University
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Filing: 1970-06-15
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Granted: 1973-02-20
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Expires: 1990-06-15
Abstract
Abstract This invention relates to a method for providing anticoagulant surfaces onto articles by treating said articles with an organic solvent solution of a co-precipitated material produced by mixing an aqueous solution of heparin and an aqueous solution of a certain cation surface active agent. Said solution may include an organic solvent-soluble plastic material.
Inventors
- 👤 E Masuhara
- 👤 I Yohji
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 19:50
CPC Classifications
A; A61; A61L; A61L33/00; A61L33/0005; A61L33/0011; A61L33/0017; C; C03; C03C; C03C17/00; C03C17/28; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/921
Claims Analysis
Total Claims: 7
Claim 1
Independent Claim
50 words
A method for providing anticoagulant surfaces onto articles made of plastic materials or glass or metals, characterized by coating said articles with an organic solvent solution containing an organic solvent-soluble plastic material and a co-precipitated material produced by mixing heparin with a cationic surface active agent in an aqueous medium.
Claim 2
Independent Claim
50 words
A method for providing anticoagulant surfaces onto articles made of plastic materials or glass or metals, characterized by coating said articles with an organic solvent solution containing an organic solvent-soluble plastic material and a co-precipitated material produced by mixing heparin with a cationic surface active agent in an aqueous medium.
Claim 3
Dependent Claim
37 words
A method according to claim 1 wherein the cationic surface active agent is selected from the group consisting of dimethyl alkyl benzyl ammonium chloride, benzyldimethyl-2-(2-(p-1,1,3,3-tetramethylbutyl phenoxy) ethoxy) ethyl ammonium chloride, alkyl-trimethyl ammonium chloride and dilauryl-dimethyl ammonium chloride.
Claim 4
Dependent Claim
62 words
A method according to claim 1 wherein the organic solvent-soluble plastic material is selected from the group consisting of polyvinyl chloride, polymethacrylic esters, polyacrylic esters, polyacrylonitrile, polyvinylbutyral, polyepichlorohydrin, polyurethane and polyamides, and the cationic surface active agent is selected from the group consisting of dimethyl alkyl benzyl ammonium chloride, benzyldimethyl-2-(2-(p-1,1,3,3-tetramethylbutyl phenoxy) ethoxy) ethyl ammonium chloriDe, alkyl-trimethyl ammonium chloride and dilauryl-dimethyl ammonium chloride.
Claim 5
Independent Claim
59 words
A method for providing anticoagulant surfaces onto articles made of plastic materials or glass or metals, characterized by coating said articles with an organic solvent solution containing an organic solvent-soluble plastic material, a member selected from 4,4''-diphenylmethane diisocyanate and tolylene diisocyanate and a co-precipitated material produced by mixing heparin with a cationic surface active agent in an aqueous medium.
Claim 6
Independent Claim
59 words
A method for providing anticoagulant surfaces onto articles made of plastic materials or glass or metals, characterized by coating said articles with an organic solvent solution containing an organic solvent-soluble plastic material, a member selected from 4,4''-diphenylmethane diisocyanate and tolylene diisocyanate and a co-precipitated material produced by mixing heparin with a cationic surface active agent in an aqueous medium.
Claim 7
Dependent Claim
62 words
A method according to claim 4 wherein the organic solvent-soluble plastic material is selected from the group consisting of polyvinyl chloride, polymethacrylic esters, polyacrylic esters, polyacrylonitrile, polyvinylbutyral, polyepichlorohydrin, polyurethane and polyamides, and the cationic surface active agent is selected from the group consisting of dimethyl alkyl benzyl ammonium chloride, benzyldimethyl-2-(2-(p-1,1,3,3-tetramethylbutyl phenoxy) ethoxy) ethyl ammonium chloride, alkyl-trimethyl ammonium chloride and dilauryl-dimethyl ammonium chloride.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1976-02-20 | 1976-08-21 | 1977-02-20 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1980-02-20 | 1980-08-21 | 1981-02-20 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1984-02-20 | 1984-08-21 | 1985-02-20 | $7700.00 | Window Closed / Lapsed |