US3634123A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Method for making nonthrombogenic surfaces
Assignee: Aminkemi AB
•
Filing: 1968-06-21
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Granted: 1972-01-11
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Expires: 1988-06-21
Abstract
Abstract The specification discloses a method for reducing thrombosis of blood induced by contact with a foreign surface by treating the surface with a cationic surface-active agent, and a conventional anticoagulant, such as heparin.
Inventors
- 👤 Jan Christer Eriksson
- 👤 Hans Ragnar Lagergren
- 👤 Anders Lennart Johansson
- 👤 Elsa Gunilla Gillberg
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 19:50
CPC Classifications
C; C12; C12Q; C12Q1/00; C12Q1/56; Y; Y10; Y10T; Y10T428/00; Y10T428/31504; Y10T428/31652; Y10T428/31663; Y10T428/31855; Y10T428/31935; Y10T428/31938
Claims Analysis
Total Claims: 19
Claim 1
Independent Claim
20 words
The method of claim 1 wherein the aqueous solution of cationic surface-active agent is degassed before treating said plastic surface.
Claim 2
Dependent Claim
13 words
The method of claim 1 wherein the plastic surface is a polyolefin surface.
Claim 3
Dependent Claim
14 words
The method of claim 1 wherein the plastic surface is a polyvinyl chloride surface.
Claim 4
Dependent Claim
14 words
The method of claim 1 wherein the plastic surface is a silicone resin surface.
Claim 5
Dependent Claim
30 words
The method of claim 1 wherein the cationic surface-active agent is a member of the group consisting of primary, secondary and tertiary amines and salts thereof and quaternary ammonium compounds.
Claim 6
Dependent Claim
20 words
The method of claim 1 wherein the cationic surface-active agent has an alkyl chain of at least four carbon atoms.
Claim 7
Dependent Claim
24 words
The method of claim 1 wherein the plastic surface is first treated with the cationic surface-active agent and is thereafter treated with the heparin.
Claim 8
Dependent Claim
11 words
The method of claim 1 wherein said plastic is a thermoplastic.
Claim 9
Dependent Claim
20 words
The method of claim 1 wherein said surface-active agent has an alkyl chain of about 12 to 18 carbon atoms.
Claim 10
Dependent Claim
41 words
The method of claim 1 wherein the plastic surface is treated with an aqueous solution containing the surface-active agent in a concentration of at least about 10 4 moles per liter and subsequently treated with an aqueous solution containing the heparin.
Claim 11
Dependent Claim
30 words
The method of claim 1 wherein the plastic surface is treated with an aqueous dispersion or emulsion of a complex compound formed by reacting a cationic surface-active agent with heparin.
Claim 12
Dependent Claim
43 words
A plastic article suitable for use in contact with blood without significant coagulation, said article having a plastic surface which is to contact the blood, said surface having been treated with a cationic surface-active agent and heparin by the method of claim 1.
Claim 13
Dependent Claim
22 words
A plastic article as described in claim 13 wherein the surface-active agent has an alkyl chain of at least four carbon atoms.
Claim 14
Dependent Claim
13 words
An article as described in claim 13 wherein said plastic is a thermoplastic.
Claim 15
Dependent Claim
24 words
A plastic article as described in claim 13 wherein the surface-active agent has an alkyl chain of about 12 to about 18 carbon atoms.
Claim 16
Dependent Claim
14 words
A plastic article as described in claim 13 wherein said plastic is a polyolefin.
Claim 17
Dependent Claim
14 words
An article as described in claim 13 wherein said plastic is a polyvinyl chloride.
Claim 18
Dependent Claim
14 words
An article as described in claim 13 wherein said plastic is a silicone resin.
Claim 19
Dependent Claim
31 words
An article as described in claim 13 wherein said surface-active agent is a member of the group consisting of primary, secondary and tertiary amines and salts thereof and quaternary ammonium compounds.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1975-01-10 | 1975-07-12 | 1976-01-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 1979-01-10 | 1979-07-12 | 1980-01-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 1983-01-10 | 1983-07-12 | 1984-01-11 | $7700.00 | Window Closed / Lapsed |