US20080077236A1
Active / In Force
US
⏱️ 1.1 years remaining
Valve prosthesis for implantation in body channels
Assignee: Edwards Lifesciences PVT Inc
•
Filing: 2007-11-19
•
Granted: —
•
Expires: 2027-11-19
Abstract
Abstract A valve prosthesis which is especially useful in the case of aortic stenosis and capable of resisting the powerful recoil force and to stand the forceful balloon inflation performed to deploy the valve and to embed it in the aortic annulus, comprises a collapsible valvular structure and an expandable frame on which said valvular structure is mounted. The valvular structure is composed of physiologically compatible valvular tissue that is sufficiently supple and resistant to allow the valvular structure to be deformed from a closed state to an opened state. The valvular tissue forms a continuous surface and is provided with strut members that create stiffened zones which induce the valvular structure to follow a patterned movement in its expansion to its opened state and in its turning back to its closed state.
Inventors
- 👤 Brice Letac
- 👤 Alain Cribier
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 04:07
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2409; A61F2/2412; A61F2/2415; A61F2/2418; A61F2/2427; A61F2/243; A61F2/2433; A61B; A61B90/00; A61B90/39; A61F2/2475; A61F2220/00; A61F2220/0008; A61F2230/00; A61F2230/0002; A61F2230/0028; A61F2230/0054; A61F2230/0063; A61F2230/0069; A61F2250/00; A61F2250/0058; A61F2250/006; Y; Y10; Y10S; Y10S623/00; Y10S623/90; Y10S623/902; Y10S623/904
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
134 words
1 . A prosthetic valve assembly for replacing a deficient native aortic valve, comprising: a metallic frame having an inlet end and an outlet end; a flexible valvular structure sewn to the frame for permitting blood to flow in one direction, the valvular structure formed of pericardial tissue; and an internal cover sewn to the frame for preventing regurgitation of blood through a wall of the frame, the internal cover formed of pericardial tissue and disposed along an inner surface of the frame between the valvular structure and the inlet end of the frame; wherein the frame is collapsible for advancing the prosthetic valve assembly through a patient's vasculature using a catheterization technique and wherein the frame is expandable for maintaining the native aortic valve in an open state and supporting the valvular structure.
Claim 2
Dependent Claim
134 words
1 . A prosthetic valve assembly for replacing a deficient native aortic valve, comprising: a metallic frame having an inlet end and an outlet end; a flexible valvular structure sewn to the frame for permitting blood to flow in one direction, the valvular structure formed of pericardial tissue; and an internal cover sewn to the frame for preventing regurgitation of blood through a wall of the frame, the internal cover formed of pericardial tissue and disposed along an inner surface of the frame between the valvular structure and the inlet end of the frame; wherein the frame is collapsible for advancing the prosthetic valve assembly through a patient's vasculature using a catheterization technique and wherein the frame is expandable for maintaining the native aortic valve in an open state and supporting the valvular structure.
Claim 3
Dependent Claim
27 words
2 . The prosthetic valve assembly of claim 1 , wherein the internal cover is sewn to the inlet end of the frame along a zig-zag line.
Claim 4
Dependent Claim
20 words
3 . The prosthetic valve assembly of claim 2 , wherein the internal cover is coupled to the valvular structure.
Claim 5
Dependent Claim
35 words
4 . The prosthetic valve assembly of claim 3 , wherein the outlet end of the frame is flared for reinforcing the embedding the of the prosthetic valve assembly within the deficient native aortic valve.
Claim 6
Dependent Claim
19 words
5 . The prosthetic valve assembly of claim 4 , wherein the inlet end of the frame is flared.
Claim 7
Dependent Claim
18 words
6 . The prosthetic valve assembly of claim 5 , wherein the frame has a substantially cylindrical structure.
Claim 8
Dependent Claim
73 words
7 . A prosthetic valve assembly for replacing a deficient native valve, comprising: a collapsible and expandable stent forming a substantially cylindrical structure; a flexible valvular structure sewn to the stent for permitting the flow of blood in one direction; and an internal cover sewn to the stent, the internal cover forming a sleeve between the valvular structure and an inlet end of the stent for preventing regurgitation of blood through the stent.
Claim 9
Dependent Claim
73 words
7 . A prosthetic valve assembly for replacing a deficient native valve, comprising: a collapsible and expandable stent forming a substantially cylindrical structure; a flexible valvular structure sewn to the stent for permitting the flow of blood in one direction; and an internal cover sewn to the stent, the internal cover forming a sleeve between the valvular structure and an inlet end of the stent for preventing regurgitation of blood through the stent.
Claim 10
Dependent Claim
20 words
8 . The valve assembly of claim 7 , wherein the valvular structure and the internal cover are coupled together.
Claim 11
Dependent Claim
22 words
9 . The valve assembly of claim 7 , wherein the valvular structure and the internal cover are formed of pericardial tissue.
Claim 12
Dependent Claim
31 words
10 . The valve assembly of claim 9 , wherein the valvular structure and the internal cover are sewn to the stent by suture lines extending around bars of the stent.
Claim 13
Dependent Claim
23 words
11 . The valve assembly of claim 7 , wherein the stent is collapsible to a diameter of about 4 to 5 millimeters.
Claim 14
Dependent Claim
23 words
12 . The valve assembly of claim 7 , wherein the stent is expandable to a size of about 20 to 25 millimeters.
Claim 15
Dependent Claim
22 words
13 . The valve assembly of claim 7 , wherein at least a portion of the stent has a generally concave profile.
Claim 16
Dependent Claim
20 words
14 . The valve assembly of claim 13 , wherein at least an outlet end of the stent is flared.
Claim 17
Dependent Claim
23 words
15 . The valve assembly of claim 7 , wherein the valvular structure forms a continuous surface and is provided with guiding means.
Claim 18
Dependent Claim
36 words
16 . The valve assembly of claim 15 , wherein the guiding means create stiffened zones which induce the valvular structure to follow a patterned movement when moving from a closed state to an open state.
Claim 19
Dependent Claim
23 words
17 . The valve assembly of claim 16 , wherein the guiding means are further configured to prevent eversion of the valvular structure.
Claim 20
Dependent Claim
27 words
18 . The valve assembly of claim 17 , wherein the internal cover is rolled around the inlet end of the stent to provide an external cover.
Claim 21
Dependent Claim
137 words
19 . A prosthetic valve assembly for replacing a deficient native aortic valve, comprising: a collapsible and expandable metallic stent forming a substantially cylindrical structure having an inlet end and an outlet end, the stent being flared along the outlet end for facilitating anchoring of the stent within the deficient native aortic valve; a flexible valvular structure formed of pericardial tissue and coupled to the stent via suture lines extending around bars in the stent; and an internal cover formed of pericardial tissue and sewn to the stent between the valvular structure and the inlet end of the stent, the internal cover forming a sleeve for preventing regurgitation of blood through a wall of the stent; wherein the internal cover is sewn to the valvular structure such that the internal cover is integral to the valvular structure.
Claim 22
Dependent Claim
137 words
19 . A prosthetic valve assembly for replacing a deficient native aortic valve, comprising: a collapsible and expandable metallic stent forming a substantially cylindrical structure having an inlet end and an outlet end, the stent being flared along the outlet end for facilitating anchoring of the stent within the deficient native aortic valve; a flexible valvular structure formed of pericardial tissue and coupled to the stent via suture lines extending around bars in the stent; and an internal cover formed of pericardial tissue and sewn to the stent between the valvular structure and the inlet end of the stent, the internal cover forming a sleeve for preventing regurgitation of blood through a wall of the stent; wherein the internal cover is sewn to the valvular structure such that the internal cover is integral to the valvular structure.
Claim 23
Dependent Claim
27 words
20 . The prosthetic valve assembly of claim 19 , wherein the internal cover is sewn to the inlet end of the stent along a zig-zag line.
References Cited (Backward Citations)
US3409013A
Cited
US3587115A
Cited
US3548417A
Cited
US3671979A
Cited
US3657744A
Cited
US3714671A
Cited
US3755823A
Cited
US4035849A
Cited
US4106129A
Cited
US4056854A
Cited
US4297749A
Cited
US4222126A
Cited
US4265694A
Cited
US4574803A
Cited
US4343048A
Cited
US4373216A
Cited
US4339831A
Cited
US4470157A
Cited
US4345340A
Cited
US4406022A
Cited
US4655771A
Cited
US4655771B1
Cited
US4605407A
Cited
US4535483A
Cited
US4612011A
Cited
US4787899A
Cited
US4629459A
Cited
US5026366A
Cited
US4592340A
Cited
US4979939A
Cited
US4687483A
Cited
US4643732A
Cited
US4759758A
Cited
US4797901A
Cited
US4733665A
Cited
US4733665B1
Cited
US4733665C2
Cited
US4922905A
Cited
US4692164A
Cited
US4878906A
Cited
US4777951A
Cited
US4883458A
Cited
US4878495A
Cited
US4796629A
Cited
US4829990A
Cited
US4851001A
Cited
US5032128A
Cited
US5080668A
Cited
US5007896A
Cited
US4856516A
Cited
US4966604A
Cited
US4994077A
Cited
US5609626A
Cited
US5500014A
Cited
US5047041A
Cited
US4986830A
Cited
US5089015A
Cited
US5591185A
Cited
US5037434A
Cited
US6168614B1
Cited
US5085635A
Cited
US20030036795A1
Cited
US5840081A
Cited
US6582462B1
Cited
US5411552A
Cited
US5152771A
Cited
US5282847A
Cited
US5607464A
Cited
US5360444A
Cited
US5443446A
Cited
US5295958A
Cited
US5167628A
Cited
US5397351A
Cited
US5370685A
Cited
US5545214A
Cited
US5756476A
Cited
US5163953A
Cited
US5332402A
Cited
US5411055A
Cited
US5549665A
Cited
US5545209A
Cited
US5480424A
Cited
US5728068A
Cited
US5554185A
Cited
US5716417A
Cited
US5571175A
Cited
US5824037A
Cited
US5855601A
Cited
US5855602A
Cited
US5749890A
Cited
US20010007956A1
Cited
US20010010017A1
Cited
US20030109924A1
Cited
US6908481B2
Cited
US20050203616A1
Cited
US20050251251A1
Cited
US20080009940A1
Cited
US5855597A
Cited
USPTO Annuity & Maintenance Windows
Maintenance schedule is calculated for granted US utility patents.