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US20040010231A1 Expired / Lapsed US ⏱️ 0.0 years remaining

Deployment system for myocardial cellular material

Assignee: Abbott Cardiovascular Systems Inc
•
Filing: 2001-07-13
•
Granted: —
•
Expires: 2021-07-13
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Abstract

Abstract A catheter-based deployment system for deploying cellular material ( 22 ) into the heart muscle ( 25 ). The deployment system includes a guiding catheter ( 19 ) and a needle assembly ( 31 ) capable of sliding within the guiding catheter. The needle assembly ( 31 ) terminates in a tip ( 34 ) having at least one side with an opening ( 43 ) in communication with a lumen ( 20 ) disposed within the needle assembly ( 31 ). Once the guiding catheter ( 19 ) is positioned the needle assembly ( 31 ) is advanced until the tip ( 34 ) penetrates the muscle wall ( 25 ). At a predetermined depth the cellular material ( 22 ) may be deployed into the muscle wall ( 25 ) via a push rod ( 46 ) disposed through the lumen of the needle assembly ( 31 ).

Inventors

  • 👤 Howard Leonhardt
  • 👤 Robert Lashinski

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 01:51
CPC Classifications
A; A61; A61M; A61M37/00; A61M37/0069; A61M25/00; A61M25/0067; A61M25/0068; A61M25/0082; A61M25/0084; A61B; A61B17/00; A61B17/00234; A61B2017/00238; A61B2017/00243; A61K; A61K35/00; A61K35/12; A61M2025/0085; A61M2025/0086; A61M2025/0087

Claims Analysis

Total Claims: 36
Claim 1
Independent Claim 94 words
1 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; and, a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that the material can be deployed into the myocardial wall from inside the lumen.
Claim 2
Dependent Claim 94 words
1 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; and, a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that the material can be deployed into the myocardial wall from inside the lumen.
Claim 3
Dependent Claim 23 words
2 . The deployment system of claim 1 , wherein the tip of the needle assembly has a point at its distal end.
Claim 4
Dependent Claim 22 words
3 . The deployment system of claim 1 , further comprising a push rod disposed inside the lumen of the needle assembly.
Claim 5
Dependent Claim 17 words
4 . The deployment system of claim 1 , wherein the guiding catheter is capable of articulating.
Claim 6
Dependent Claim 17 words
5 . The deployment system of claim 1 , wherein the needle assembly is capable of articulating.
Claim 7
Dependent Claim 24 words
6 . The deployment system of claim 1 , wherein the tip has an outer surface with a set of external threads disposed thereon.
Claim 8
Dependent Claim 24 words
7 . The deployment system of claim 1 , wherein the guiding catheter further comprises a distal end having an anchor hook extending therefrom.
Claim 9
Dependent Claim 21 words
8 . The deployment system of claim 1 , wherein the guiding catheter further comprises a distal end having a sensor.
Claim 10
Dependent Claim 16 words
9 . The deployment system of claim 8 , wherein the sensor is an opto-electric sensor.
Claim 11
Dependent Claim 40 words
10 . The deployment system of claim 1 , further comprising an anchor wire disposed axially through the tip and capable of engaging with a portion of the myocardial wall to position the needle assembly relative to the myocardial wall.
Claim 12
Dependent Claim 44 words
11 . The deployment system of claim 1 , wherein the needle assembly has a cradle for holding a charge of the myocardial cellular material, the cradle disposed between the lumen in the needle assembly and the opening in the side of the tip.
Claim 13
Dependent Claim 101 words
12 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly; and, a push rod having a platform disposed at its distal end, the push rod disposed inside the lumen of the needle assembly.
Claim 14
Dependent Claim 101 words
12 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly; and, a push rod having a platform disposed at its distal end, the push rod disposed inside the lumen of the needle assembly.
Claim 15
Dependent Claim 24 words
13 . The deployment system of claim 12 , wherein the tip has an outer surface with a set of external threads disposed thereon.
Claim 16
Dependent Claim 23 words
14 . The deployment system of claim 12 , wherein the tip of the needle assembly has a point at its distal end.
Claim 17
Dependent Claim 24 words
15 . The deployment system of claim 12 , wherein the guiding catheter further comprises a distal end having an anchor hook extending therefrom.
Claim 18
Dependent Claim 21 words
16 . The deployment system of claim 12 , wherein the guiding catheter further comprises a distal end having a sensor.
Claim 19
Dependent Claim 16 words
17 . The deployment system of claim 16 , wherein the sensor is an opto-electric sensor.
Claim 20
Dependent Claim 40 words
18 . The deployment system of claim 12 , further comprising an anchor wire disposed axially through the tip and capable of engaging with a portion of the myocardial wall to position the needle assembly relative to the myocardial wall.
Claim 21
Dependent Claim 44 words
19 . The deployment system of claim 12 , wherein the needle assembly has a cradle for holding a charge of the myocardial cellular material, the cradle disposed between the lumen in the needle assembly and the opening in the side of the tip.
Claim 22
Dependent Claim 182 words
20 . A method of deploying myocardial cellular material, comprising: providing a guiding catheter having at least one lumen defined therein and a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that the material can be deployed into the myocardial wall from inside the lumen; advancing the guiding catheter through a patient's body to the myocardial wall; deploying the needle assembly by inserting the tip of the needle assembly into the myocardial wall to a predetermined depth; extending an implement through the opening in the side of the tip and engaging the implement directly with the myocardial wall; retracting the implement and inserting a myocardial cellular material into the lumen of the needle assembly; deploying the myocardial cellular material into the myocardial wall through the opening in the side of the tip.
Claim 23
Dependent Claim 182 words
20 . A method of deploying myocardial cellular material, comprising: providing a guiding catheter having at least one lumen defined therein and a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that the material can be deployed into the myocardial wall from inside the lumen; advancing the guiding catheter through a patient's body to the myocardial wall; deploying the needle assembly by inserting the tip of the needle assembly into the myocardial wall to a predetermined depth; extending an implement through the opening in the side of the tip and engaging the implement directly with the myocardial wall; retracting the implement and inserting a myocardial cellular material into the lumen of the needle assembly; deploying the myocardial cellular material into the myocardial wall through the opening in the side of the tip.
Claim 24
Dependent Claim 15 words
21 . The method of claim 20 , wherein the implement is a push rod.
Claim 25
Dependent Claim 20 words
22 . The method of claim 21 , wherein the push rod has a platform disposed at its distal end.
Claim 26
Dependent Claim 22 words
23 . The method of claim 20 , wherein the tip of the needle assembly has a point at its distal end.
Claim 27
Dependent Claim 16 words
24 . The method of claim 20 , wherein the guiding catheter is capable of articulating.
Claim 28
Dependent Claim 16 words
25 . The method of claim 20 , wherein the needle assembly is capable of articulating.
Claim 29
Dependent Claim 23 words
26 . The method of claim 20 , wherein the tip has an outer surface with a set of external threads disposed thereon.
Claim 30
Dependent Claim 23 words
27 . The method of claim 20 , wherein the guiding catheter further comprises a distal end having an anchor hook extending therefrom.
Claim 31
Dependent Claim 20 words
28 . The method of claim 20 , wherein the guiding catheter further comprises a distal end having a sensor.
Claim 32
Dependent Claim 15 words
29 . The method of claim 20 , wherein the sensor is an opto-electric sensor.
Claim 33
Dependent Claim 39 words
30 . The method of claim 20 , further comprising an anchor wire disposed axially through the tip and capable of engaging with a portion of the myocardial wall to position the needle assembly relative to the myocardial wall.
Claim 34
Dependent Claim 43 words
31 . The method of claim 20 , wherein the needle assembly has a cradle for holding a charge of the myocardial cellular material, the cradle disposed between the lumen in the needle assembly and the opening in the side of the tip.
Claim 35
Dependent Claim 114 words
32 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; and, a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that an injectable material can be deployed from inside the lumen through the opening in the tip of the needle assembly; means for injecting cellular materials through the needle assembly into the myocardial wall.
Claim 36
Dependent Claim 114 words
32 . A deployment system for myocardial cellular material, comprising: a guiding catheter having at least one lumen defined therein; and, a needle assembly capable of sliding through the lumen of the guiding catheter, the needle assembly having a lumen defined therein and terminating in a tip, the tip having at least one side, the needle assembly having an opening in the at least one side of the tip disposed in communication with the lumen of the needle assembly so that an injectable material can be deployed from inside the lumen through the opening in the tip of the needle assembly; means for injecting cellular materials through the needle assembly into the myocardial wall.

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