Claims Analysis
Total Claims: 15
Claim 1
Independent Claim
31 words
A drug-loaded stent, comprising: an expandable stent structural member; and a planar sheet of polymeric material disposed on the stent structural member, said polymeric material being loaded with a therapeutic agent.
Claim 2
Dependent Claim
23 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material is wrapped in a coil around the stent structural member.
Claim 3
Dependent Claim
36 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material is wrapped circumferentially around the stent structural member at least one time, and said planar sheet of polymeric material is attached to itself.
Claim 4
Dependent Claim
42 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material is wrapped circumferentially around the stent structural member at least one time, and said planar sheet of polymeric material is attached to the stent structural member by interference fit.
Claim 5
Dependent Claim
41 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material is wrapped circumferentially around the stent structural member at least one time, and said planar sheet of polymeric material is attached to the stent structural member by adhesive.
Claim 6
Dependent Claim
121 words
The drug-loaded stent of Claim 1, wherein said stent structural member has a surface defining a plurality of slotted openings therethrough and a plurality of structural ribs, said planar sheet of polymeric material has at least one attachment tab having an aperture therethrough and a slit extending from said aperture to an outside edge of said attachment tab, said planar sheet of polymeric material being attached to the stent structural member by inserting said attachment tab into one said stent stent slotted opening and hooking said slit and said aperture of said attacment tab to a structural rib of said stent structural member, and said sheet of polymeric material is wrapped circumferentially around the stent structural member at least one time.
Claim 7
Dependent Claim
38 words
The drug-loaded stent of Claim 3, wherein said planar sheet of polymeric material is selected from the group of polymers consisting of thermoplastic and elastomeric polymers, whereby said film stretches radially when said stent structural member is expanded.
Claim 8
Dependent Claim
29 words
The drug-loaded stent of Claim 2, wherein said planar sheet of polymeric material is adapted to uncoil and expand to substantially match the expansion of said stent structural member.
Claim 9
Dependent Claim
45 words
The drug-loaded stent of Claim 2, wherein said stent structural member has a longitudinal axis, and said planar sheet of polymeric material has at least one slit transverse to the axis of said stent structural member to accommodate uneven expansion of the stent structural member.
Claim 10
Dependent Claim
27 words
The drug-loaded stent of Claim 1, wherein said therapeutic agent is selected from the group consisting of therapeutic agents consisting of antiplatelets, antithrombins, cytostatic and antiproliferative agents.
Claim 11
Dependent Claim
94 words
The drug-loaded stent of Claim 1, wherein said therapeutic agent is selected from the group of therapeutic agents consisting of sodium heparin, low molecular weight heparin, hirudin, argatroban, forskolin, vapiprost, prostacyclin and prostacyclin analogues, dextran, D-phe-pro-arg-chloromethylketone, dipyridamole, glycoprotein IIb/IIIa platelet membrane receptor antibody, recombinant hirudin, thrombin inhibitor, angiopeptin, angiotensin converting enzyme inhibitors, calcium channel blockers, colchicine, fibroblast growth factor antagonists, fish oil, omega 3-fatty acid, histamine antagonists, HMG-CoA reductase inhibitor, methotrexate, monoclonal antibodies, nitroprusside, phosphodiesterase inhibitors, prostaglandin inhibitor, serotonin blockers, steroids, thioprotease inhibitors, triazolopyrimidine, PDGF antagonists, alpha-interferon, genetically engineered epithelial cells, and combinations thereof.
Claim 12
Dependent Claim
36 words
The drug-loaded stent of Claim 1, wherein said stent structural member is formed from a metal selected from the group of metals consisting of stainless steel, tantalum, nickel-titanium alloy, platinum-iridium alloy, gold, magnesium, MP35N, and MP20N.
Claim 13
Dependent Claim
25 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material has a surface defining a plurality of openings to promote rapid endothelialization.
Claim 14
Dependent Claim
23 words
The drug-loaded stent of Claim 1, wherein said planar sheet of polymeric material is coated with a layer of hydrophilic lubricious polymeric material.
Claim 15
Dependent Claim
39 words
The drug-loaded stent of Claim 14, wherein said lubricious material is selected from the group consisting of polyethylene oxide, polyethylene glycol, polyethylene acetate, polyvinyl pyrrolidone, polyvinyl alcohol, polyacrylamide, hydrophylic soft segment urethane, gum arabic, gum tragacanth, and combinations thereof.