Patent EP0241252A2 successfully refreshed from Google Patents.
EP0241252A2
Expired / Lapsed
EP
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Artificial, absorbable ligament prosthesis
Assignee: Johnson and Johnson Professional Inc
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Filing: 1987-04-06
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Granted: —
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Expires: 2007-04-06
Abstract
Abstract An absorbable ligament and tendon prosthesis is disclosed. The prosthesis is made from a polymer of L(-)lactide and may contain up to 10% glycolide as a comonomer. The polymerization mass includes an organo metallic catalyst present in a monomer to catalyst mole ratio of from 10,000 to 50,000 and a monofunctional alcohol, as an end cap, in a monomer to alcohol mole ratio of from 600 to 1400 to 1. The filaments of the prosthesis have diameters of from 3 to 15 microns and the total diameter of the prosthesis is between 20 and 80 mils.
Inventors
- 👤 Brian C. Benicewicz
- 👤 Zale Oser
- 👤 Alastair J.T. Clemow
- 👤 Shalaby Wabba Shalaby
Bibliographic Details
Application Number
—
Jurisdiction
EP
Data Source
google_patents
Last Synchronized
2026-10-23 17:50
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/02; A61F2/08; A61L; A61L27/00; A61L27/50; A61L27/58; A61L27/14; A61L27/18; A61L2430/00; A61L2430/10
Claims Analysis
Total Claims: 16
Claim 1
Independent Claim
89 words
An absorbable ligament and tendon prosthesis, capable of maintaining at least 30% of its initial tensile strength for a period of at least 3 months after implantation in an animal body, comprising a plurality of filaments arranged in an open structure to allow tissue ingrowth between individual filaments, said filaments comprising a melt spinnable polymer stable at temperatures above 210°C and containing from 90 to 100% mole L-lactide and 0 to 10 % glycolide, said polymer being end-capped with a monofunctional alcohol having from 6 to 14 carbon atoms.
Claim 2
Dependent Claim
89 words
An absorbable ligament and tendon prosthesis, capable of maintaining at least 30% of its initial tensile strength for a period of at least 3 months after implantation in an animal body, comprising a plurality of filaments arranged in an open structure to allow tissue ingrowth between individual filaments, said filaments comprising a melt spinnable polymer stable at temperatures above 210°C and containing from 90 to 100% mole L-lactide and 0 to 10 % glycolide, said polymer being end-capped with a monofunctional alcohol having from 6 to 14 carbon atoms.
Claim 3
Dependent Claim
18 words
The prosthesis of claim 1 in which the filaments have a diameter of from 3 to 15 um.
Claim 4
Dependent Claim
17 words
The prosthesis of claim 2 in which the filaments have a diameter of from 5 to l2um.
Claim 5
Dependent Claim
28 words
The prosthesis of any one of claims 1 to 3 in which the prosthesis has a total diameter of from 0.76 to 1.52 mm (30 to 60 mils).
Claim 6
Dependent Claim
32 words
The prosthesis of any one of claims 1 to 4 in which the filaments are plied into a twisted yarn having from 1 to 15 twists per 2.54 cm (inch) of length.
Claim 7
Dependent Claim
20 words
The prosthesis of claim 5 in which the number of twists per 2.54 cm (inch) is between 2 and 8.
Claim 8
Dependent Claim
25 words
The prosthesis of any one of claims 1 to 6 in which the total number of filaments in the. prosthesis is between 3,000 and 10,000.
Claim 9
Dependent Claim
20 words
The prosthesis of claim 7 in which the total number of filaments in the prosthesis is between 4,000 and 8,000.
Claim 10
Dependent Claim
17 words
The prosthesis of any one of claims 1 to 8, wherein the polymer is end-capped with dodecanol.
Claim 11
Dependent Claim
91 words
A process of forming a ligament and tendon prosthesis comprising polymerizing a reaction mass containing L(-)lactide and 0 to 10 mole percent glycolide in an inert atmosphere in the presence of a catalyst, said catalyst been present in monomer to catalyst mole ratio of from 10,000 to 50,000 to 1, said reaction mass containing a monofunctional alcohol having from 6 to 14 carbon atoms in a monomer to alcohol mole ratio of from 600 to 1400 to 1, spinning the polymer into fiber's and plying the fibers into a porous structure.
Claim 12
Dependent Claim
91 words
A process of forming a ligament and tendon prosthesis comprising polymerizing a reaction mass containing L(-)lactide and 0 to 10 mole percent glycolide in an inert atmosphere in the presence of a catalyst, said catalyst been present in monomer to catalyst mole ratio of from 10,000 to 50,000 to 1, said reaction mass containing a monofunctional alcohol having from 6 to 14 carbon atoms in a monomer to alcohol mole ratio of from 600 to 1400 to 1, spinning the polymer into fiber's and plying the fibers into a porous structure.
Claim 13
Dependent Claim
18 words
The process of claim 10 in which the spinning temperature of the polymer is between 215°C and 240°C.
Claim 14
Dependent Claim
16 words
The process of claim 10 or claim 11, in which the catalyst is an organometallic catalyst.
Claim 15
Dependent Claim
12 words
The process of claim 12, in which the catalyst is stannous octate.
Claim 16
Dependent Claim
25 words
The process of any one of claims 10 to 13, which is used to produce the prosthesis of any one of claims 1 to 9.
References Cited (Backward Citations)
No citation records indexed.
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