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EP0228067A2 Expired / Lapsed EP ⏱️ 0.0 years remaining

Seamless soft capsule

Assignee: Taisho Pharmaceutical Co Ltd
•
Filing: 1986-12-23
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Granted: —
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Expires: 2006-12-23
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Abstract

Abstract A soft capsule composed of a plurality of cells coalesced to each other and filling substances encap­sulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless. The soft capsule can be produced by (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling sub­stance having flowability, the film-forming liquid subtance in at least one of the composite jet streams being dif­ferent from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flow­ing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.

Inventors

  • 👤 Tadashi Kosaka
  • 👤 Kazuki Omata
  • 👤 Tatsuo Hashimoto
  • 👤 Teruaki Yamazaki
  • 👤 Kazuo Hayashi
  • 👤 Tomiya Hosoi
  • 👤 Kenichi Ikuta

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 13:04
CPC Classifications
A; A61; A61J; A61J3/00; A61J3/07

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 55 words
A soft capsule composed of a plurality of cells coalesced to each other and filling substances encap­sulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless.
Claim 2
Dependent Claim 55 words
A soft capsule composed of a plurality of cells coalesced to each other and filling substances encap­sulated in the individual cells, the wall of at least one of the cells being formed of a material different from a material forming the wall of at least one of the other cells, and said capsule being seamless.
Claim 3
Dependent Claim 43 words
The soft capsule of claim l wherein at least one of the cells and at least one of the other cells are formed of cell wall materials having different dissolving times in the digestive tract or different dissolving characteristics in the digestive tract.
Claim 4
Dependent Claim 21 words
The soft capsule of claim l wherein the filling substance encapsulated in the plurality of cells are different from one another.
Claim 5
Dependent Claim 14 words
The soft capsule of claim l which is composed of 2 or 3 cells.
Claim 6
Independent Claim 181 words
A method of producing the soft capsule of claim l, which comprises (a) preparing a plurality of composite jet streams each consisting of a stream of a film-forming liquid substance for forming a cell wall and within said stream of a film-forming liquid substance a single stream, or a plurality of independent streams, of a filling sub­stance having flowability, the film-forming liquid subtance in at least one of the composite jet streams being dif­ferent from the film-forming liquid substance in at least one of the other composite jet streams, (b) advancing the plurality of composite jet streams in closely spaced relationship into and through a stream of a liquid medium substantially incapable of dissolving the film-forming liquid substance in the flow­ing direction of the liquid medium stream, (c) coalescing the adjacent composite jet streams to each other to form a single composite jet stream in the liquid medium stream, (d) cutting the single composite jet stream to a predetermined length successively from its leading end in the liquid medium stream, and (e) solidifying the cell walls of the resulting soft capsule.
Claim 7
Dependent Claim 54 words
The method of claim 5 wherein each of said plurality of composite jet streams is formed by using a composite nozzle comprised of an outside nozzle and at least one small-diameter inside nozzle disposed therein and simultaneously extruding the film-forming liquid substance from the outside nozzle and the filling sub­stance from the inside nozzle.
Claim 8
Dependent Claim 37 words
The method of claim 5 wherein the cutting of the single composite jet stream is carried out by intermit­tently applying a pulsating flow of a liquid medium from an annular slit surrounding the single composite jet stream.
Claim 9
Dependent Claim 54 words
The method of claim 5 wherein the film-forming liquid substance in at least one of the plurality of composite jet streams has a different dissolving time in the digestive tract or a different dissolving character­istic in the digestive tract from the film-forming liquid substance in at least one of the other composite jet streams.
Claim 10
Dependent Claim 16 words
The method of claim 5 wherein the plurality of composite jet streams contain different filling sub­stances.

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