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Implantable module for gylcemia regulation

Assignee: Johnson and Johnson
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Filing: 1984-11-14
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Granted: —
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Expires: 2004-11-14
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Abstract

Abstract Implantable glycemic regulation module comprising semipermeable membrane encapsulating insulin-producing tissue from the group consisting of human insulinoma cells and human pancreatic islets.

Inventors

  • 👤 Jean-Jacques Altman

Bibliographic Details

Application Number —
Jurisdiction EP
Data Source google_patents
Last Synchronized 2026-10-23 03:15
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0087; A61K9/0092; A61F; A61F2/00; A61F2/02; A61F2/022; A61K9/0012; A61K9/0019; A61K9/0024; A61L; A61L27/00; A61L27/50; A61L27/54; C; C12; C12N; C12N11/00; C12N11/02; C12N11/04; A61L2300/00; A61L2300/40; A61L2300/43; A61L2300/60; A61L2300/62; A61L2300/64

Claims Analysis

Total Claims: 6
Claim 1
Independent Claim 60 words
An implantable module for regulating human glycemia comprising a live insulin-producing source, from the group consisting of a plurality of human insulinoma cells and a plurality of human islets, said source being encapsulated in a hollow fiber membrane material, said membrane material being permeable to insulin and other endocrine hormones, cell waste products, and cell nutrients, and impermeable to immunocytes.
Claim 2
Dependent Claim 60 words
An implantable module for regulating human glycemia comprising a live insulin-producing source, from the group consisting of a plurality of human insulinoma cells and a plurality of human islets, said source being encapsulated in a hollow fiber membrane material, said membrane material being permeable to insulin and other endocrine hormones, cell waste products, and cell nutrients, and impermeable to immunocytes.
Claim 3
Dependent Claim 14 words
The module of claim 1, wherein said insulin source comprises live human insulinoma cells.
Claim 4
Dependent Claim 13 words
The module of claim 1, wherein said insulin source comprises human pancreatic islets.
Claim 5
Dependent Claim 16 words
The module of any one of claims 1 to 3 for use in regulating human glycemia.
Claim 6
Independent Claim 65 words
A method of producing a module according to any one of claims 1 to 3, comprising encapsulating a live insulin-producing source, from the group consisting of a plurality of human insulinoma cells and a plurality of human islets, in a hollow fiber membrane material, said membrane material being permeable to insulin and other endocrine hormones, cell waste products, and cell nutrients, and impermeable to immunocytes.

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