Novel pulmonary surfactants and therapeutic uses, including pulmonary lavage

Abstract

Abstract The present invention discloses useful surfactant molecules including polypeptides, proteins, and a variety of other organic molecules, as well as methods of making and using same. Surfactant compositions, including liposomal surfactant compositions, are also disclosed. Use of the surfactant molecules of the present invention in pulmonary lavage procedures for a variety of therapeutic applications is also disclosed, including the treatment of respiratory distress syndrome; the removal of inflammatory exudate from inflamed lung tissues; and the treatment of meconium aspiration syndrome in infants.

Inventors

• 👤 Charles G. Cochrane
• 👤 Susan D. Revak

Bibliographic Details