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WO1994001481A1
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WO
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Calcification-resistant synthetic biomaterials
Assignee: University of Michigan-Ann Arbor
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Filing: 1993-07-09
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Granted: —
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Expires: 2013-07-09
Abstract
Abstract Synthetic biomaterials are provided with irreversibly bound amino diphosphonate, polyphosphonate, or other anticalcification agent to prevent in vivo calcification. Such biomaterials include biocompatible elastomers such as polyurethane and/or polydimethylsiloxane, and the like which are intended for invasive, or indwelling use in a human or animal body. Illustratively, reaction conditions utilizing bi- or polyfunctional epoxides result in epoxide bridge incorporation of the anticalcification agent to the biomaterial elastomer.
Inventors
- 👤 Robert J. Levy
- 👤 Ravi Joshi
Bibliographic Details
Application Number
—
Jurisdiction
WO
Data Source
google_patents
Last Synchronized
2026-10-22 21:09
CPC Classifications
C; C08; C08G; C08G59/00; C08G59/14; C08G59/1433; C08G59/1488; A; A61; A61L; A61L27/00; A61L27/14; A61L27/18; A61L27/50; A61L27/54; A61L33/00; A61L33/0005; A61L33/0011; C08L; C08L101/00; C08L101/02; A61L2400/00; A61L2400/02
Claims Analysis
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References Cited (Backward Citations)
US4705841A
Cited
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