WO1993015767A1
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Implant therapy for bone growth stimulation
Assignee: Merck and Co Inc
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Filing: 1993-02-04
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Granted: —
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Expires: 2013-02-04
Abstract
Abstract Therapeutic stimulation of bone formation is accomplished through the controlled release of the prostaglandins E1, E2 or F2α, or the steroid, β-estradiol to the site where bone growth stimulation is desired. A rigid, solid, controlled release dosage form, consisting of a non-residue producing, bioerodible polymer, selected from a poly(ortho ester) or a polyacetal and a prostaglandin, or β-estradiol is implanted at the site of desired bone growth stimulation. The figure shows E2 release at .81 (Group A), .035 (Group B) and .003 (Group C) weight %.
Inventors
- 👤 Leah E. Appel
- 👤 Gaylen M. Zentner
- 👤 Gideon A. Rodan
Bibliographic Details
Application Number
—
Jurisdiction
WO
Data Source
google_patents
Last Synchronized
2026-10-23 04:10
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/0012; A61K9/0019; A61K9/0024; A61K9/20; A61K9/2004; A61K9/2022; A61K9/2031; A61K9/204; A61L; A61L24/00; A61L24/001; A61L24/0015; A61L26/00; A61L26/0009; A61L26/0019; A61L2300/00; A61L2300/20; A61L2300/22; A61L2300/222; A61L2300/60; A61L2300/602
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References Cited (Backward Citations)
US4093709A
Cited
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