WO1989012624A2
Expired / Lapsed
WO
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Coupling agents and sterically hindered disulfide linked conjugates prepared therefrom
Assignee: Novartis Vaccines and Diagnostics Inc
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Filing: 1989-06-12
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Granted: —
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Expires: 2009-06-12
Abstract
Abstract This invention discloses heterobifunctional coupling agents for making a wide array of molecular conjugates. The agents contain a sterically hindered thiol, linked through a spacer arm to a second group reactive toward nucleophiles such as 1 DEG and 2 DEG amines or reactive thiols that are present on biological and organic materials. The coupling agents are useful for making conjugates containing a sterically hindered linkage.
Inventors
- 👤 Margaret Moreland
- 👤 I. Lawrence Greenfield
- 👤 Danute E. Nitecki
Bibliographic Details
Application Number
—
Jurisdiction
WO
Data Source
google_patents
Last Synchronized
2026-10-23 03:03
CPC Classifications
C; C07; C07D; C07D207/00; C07D207/02; C07D207/44; C07D207/444; C07D207/448; C07D207/452; C07C; C07C327/00; C07C327/20; C07C327/32; C07D207/46; G; G01; G01N; G01N33/00; G01N33/48; G01N33/50; G01N33/53; G01N33/531; G01N33/532
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