US6866650B2
Expired / Lapsed
US
⏱️ 0.0 years remaining
System for cardiac procedures
Assignee: Edwards Lifesciences LLC
•
Filing: 2001-02-02
•
Granted: 2005-03-15
•
Expires: 2021-02-02
Abstract
Abstract A system for accessing a patient's cardiac anatomy which includes an endovascular aortic partitioning device that separates the coronary arteries and the heart from the rest of the patient's arterial system. The endovascular device for partitioning a patient's ascending aorta comprises a flexible shaft having a distal end, a proximal end, and a first inner lumen therebetween with an opening at the distal end. The shaft may have a preshaped distal portion with a curvature generally corresponding to the curvature of the patient's aortic arch. An expandable means, e.g. a balloon, is disposed near the distal end of the shaft proximal to the opening in the first inner lumen for occluding the ascending aorta so as to block substantially all blood flow therethrough for a plurality of cardiac cycles, while the patient is supported by cardiopulmonary bypass. The endovascular aortic partitioning device may be coupled to an arterial bypass cannula for delivering oxygenated blood to the patient's arterial system. The heart muscle or myocardium is paralyzed by the retrograde delivery of a cardioplegic fluid to the myocardium through patient's coronary sinus and coronary veins, or by antegrade delivery of cardioplegic fluid through a lumen in the endovascular aortic partitioning device to infuse cardioplegic fluid into the coronary arteries. The pulmonary trunk may be vented by withdrawing liquid from the trunk through an inner lumen of an elongated catheter. The cardiac accessing system is particularly suitable for removing the aortic valve and replacing the removed valve with a prosthetic valve.
Inventors
- 👤 John H. Stevens
- 👤 Wesley D. Sterman
- 👤 Hanson S. Gifford, III
- 👤 Timothy R. Machold
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:50
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/0105; A61M25/0133; A61M25/0147; A61F; A61F2/00; A61F2/02; A61F2/24; A61F2/2427; A61M1/00; A61M1/36; A61M1/3621; A61M1/3623; A61M1/3653; A61M1/3659; A61M25/0021; A61M25/0041; A61M25/0152; A61M25/06; A61M25/0662; A61M25/10; A61B; A61B17/00; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B18/00; A61B2018/00053; A61B2018/00214; A61B2018/0022; A61B2018/00232; A61B2018/0025; A61B2018/00261; A61M1/3613; A61M25/0023; A61M25/0026; A61M25/003; A61M2025/0031; A61M25/0067; A61M25/0074; A61M25/0075; A61M2025/0076; A61M2025/0078; A61M2025/015; A61M2025/0161; A61M25/02; A61M2025/028; A61M2025/1043; A61M2025/1047; A61M2025/1052; A61M2025/1077; A61M2025/1095; A61M2202/00; A61M2202/04; A61M2202/0468; A61M2202/047; A61M2205/00; A61M2205/11; A61M2205/36; A61M2205/366; A61M2210/00; A61M2210/12; A61M2210/125; A61M2210/127; A61M25/0032; A61M25/0125; A61M25/1002
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
234 words
A cardiopulmonary bypass catheter system for arresting a patient's heart and maintaining arterial circulation comprising: a return cannula having an elongated cannula body, a distal end adapted for positioning in a blood vessel, a proximal end, a return lumen in the cannula body adapted for flowing blood therethrough, a return outlet at the distal end in communication with the return lumen, a return inlet at the proximal end in communication with the return lumen, a catheter port at the proximal end in communication with the return lumen and adapted to removably receive a catheter therein, and a hemostasis valve in the catheter port adapted to seal around a catheter positioned in the catheter port; and an occlusion catheter slidably positioned through the catheter port and the return lumen, the occlusion catheter having an infusion lumen with an infusion inlet and an infusion outlet, the infusion inlet being adapted for connection to a source of cardioplegic fluid, and an expandable occlusion member attached to the occlusion catheter at a location proximal to the infusion outlet having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; wherein the return lumen is adapted to deliver blood when the occlusion catheter is positioned therein at a flow rate sufficient to maintain arterial circulation when the heart is arrested.
Claim 2
Dependent Claim
234 words
A cardiopulmonary bypass catheter system for arresting a patient's heart and maintaining arterial circulation comprising: a return cannula having an elongated cannula body, a distal end adapted for positioning in a blood vessel, a proximal end, a return lumen in the cannula body adapted for flowing blood therethrough, a return outlet at the distal end in communication with the return lumen, a return inlet at the proximal end in communication with the return lumen, a catheter port at the proximal end in communication with the return lumen and adapted to removably receive a catheter therein, and a hemostasis valve in the catheter port adapted to seal around a catheter positioned in the catheter port; and an occlusion catheter slidably positioned through the catheter port and the return lumen, the occlusion catheter having an infusion lumen with an infusion inlet and an infusion outlet, the infusion inlet being adapted for connection to a source of cardioplegic fluid, and an expandable occlusion member attached to the occlusion catheter at a location proximal to the infusion outlet having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; wherein the return lumen is adapted to deliver blood when the occlusion catheter is positioned therein at a flow rate sufficient to maintain arterial circulation when the heart is arrested.
Claim 3
Dependent Claim
40 words
The cardiopulmonary bypass catheter system of claim 1 further comprising a venting port in communication with the infusion lumen, the venting port being adapted for connection to a pump for withdrawing fluids from the ascending aorta through the infusion lumen.
Claim 4
Dependent Claim
37 words
The cardiopulmonary bypass catheter system of claim 1 wherein the return lumen is adapted to deliver blood at a flow rate of at least about 4 l/min and a pressure of less than about 250 mm Hg.
Claim 5
Dependent Claim
20 words
The cardiopulmonary bypass catheter system of claim 1 wherein the return lumen has an inner diameter of about 5-9 mm.
Claim 6
Dependent Claim
20 words
The cardiopulmonary bypass catheter system of claim 4 wherein the occlusion catheter has an outer diameter of about 2-5 mm.
Claim 7
Dependent Claim
20 words
The cardiopulmonary bypass catheter system of claim 1 further comprising a source of cardioplegic fluid coupled to the infusion port.
Claim 8
Dependent Claim
20 words
The cardiopulmonary bypass catheter system of claim 1 further comprising a source of oxygenated blood coupled to the infusion port.
Claim 9
Dependent Claim
26 words
The cardiopulmonary bypass catheter system of claim 1 further comprising a pump coupled to the return inlet adapted for pumping oxygenated blood through the return lumen.
Claim 10
Dependent Claim
49 words
The cardiopulmonary bypass catheter system of claim 8 wherein the pump is adapted to pump oxygenated blood through the return lumen at a rate of at least about 4 l/min, at a pressure of less than about 250 mm Hg with the occlusion catheter positioned in the return lumen.
Claim 11
Dependent Claim
36 words
The cardiopulmonary bypass catheter system of claim 1 wherein the infusion lumen is configured to deliver cardioplegic fluid at a rate of at least 250 ml/min at a pressure of less than about 300 mm Hg.
Claim 12
Dependent Claim
24 words
The cardiopulmonary bypass catheter system of claim 10 wherein the infusion lumen has a cross-sectional area of at least about 4.5 mm 2 .
Claim 13
Dependent Claim
35 words
The cardiopulmonary bypass catheter system of claim 1 further comprising a venous cannula positionable in a vein and an oxygenator fluidly coupled to the venous cannula, the oxygenator being fluidly coupled to the return inlet.
Claim 14
Dependent Claim
42 words
The cardiopulmonary bypass catheter system of claim 1 wherein the return cannula is positionable in a femoral artery and the occlusion catheter has a length of at least about 80 cm such that the occlusion member is positionable in the ascending aorta.
Claim 15
Dependent Claim
29 words
The cardiopulmonary bypass catheter system of claim 1 wherein the occlusion catheter has a pre-shaped distal portion configured to conform to at least a portion of the aortic arch.
Claim 16
Dependent Claim
42 words
The cardiopulmonary bypass catheter system of claim 1 wherein the occlusion catheter has a pressure lumen with a pressure outlet distal to the occlusion member and a pressure port proximal to the occlusion member adapted for connection to a pressure monitoring device.
Claim 17
Dependent Claim
266 words
A cardiopulmonary bypass catheter system for arresting a patient's heart and maintaining arterial circulation comprising: a return cannula having an elongated cannula body, a distal end adapted for positioning in a blood vessel, a proximal end, a return lumen in the cannula body adapted for flowing blood therethrough, a return outlet at the distal end in communication with the return lumen, a return inlet at the proximal end in communication with the return lumen, a catheter port at the proximal end in communication with the return lumen and adapted to removably receive a catheter therein, and a hemostasis valve in the catheter port adapted to seal around a catheter positioned in the catheter port; an occlusion catheter slidably positioned through the catheter port and the return lumen, the occlusion catheter having an infusion lumen with an infusion inlet and an infusion outlet, a venting port in communication with the infusion lumen, and an expandable occlusion member attached to the occlusion catheter at a location proximal to the infusion outlet having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; a return pump coupled to the return inlet and adapted for pumping oxygenated blood through the return lumen with the occlusion catheter positioned therein at a flow rate sufficient to maintain arterial circulation with the heart arrested; a source of cardioplegic fluid coupled to the infusion port; and a venting pump coupled to the venting port for withdrawing fluids from the ascending aorta through the infusion lumen.
Claim 18
Dependent Claim
266 words
A cardiopulmonary bypass catheter system for arresting a patient's heart and maintaining arterial circulation comprising: a return cannula having an elongated cannula body, a distal end adapted for positioning in a blood vessel, a proximal end, a return lumen in the cannula body adapted for flowing blood therethrough, a return outlet at the distal end in communication with the return lumen, a return inlet at the proximal end in communication with the return lumen, a catheter port at the proximal end in communication with the return lumen and adapted to removably receive a catheter therein, and a hemostasis valve in the catheter port adapted to seal around a catheter positioned in the catheter port; an occlusion catheter slidably positioned through the catheter port and the return lumen, the occlusion catheter having an infusion lumen with an infusion inlet and an infusion outlet, a venting port in communication with the infusion lumen, and an expandable occlusion member attached to the occlusion catheter at a location proximal to the infusion outlet having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; a return pump coupled to the return inlet and adapted for pumping oxygenated blood through the return lumen with the occlusion catheter positioned therein at a flow rate sufficient to maintain arterial circulation with the heart arrested; a source of cardioplegic fluid coupled to the infusion port; and a venting pump coupled to the venting port for withdrawing fluids from the ascending aorta through the infusion lumen.
Claim 19
Dependent Claim
118 words
A cardiopulmonary bypass catheter system, comprising: a cannula having a return lumen adapted for flowing blood therethrough, the return lumen having a return outlet; and an occlusion catheter sized and configured to be slidably positioned through the lumen, the occlusion catheter having an occlusion member, the occlusion member having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; wherein the return lumen is configured to deliver blood via the return outlet at a flow rate sufficient to maintain arterial circulation when the heart is arrested and when at least a portion of the occlusion catheter is positioned therein.
Claim 20
Dependent Claim
118 words
A cardiopulmonary bypass catheter system, comprising: a cannula having a return lumen adapted for flowing blood therethrough, the return lumen having a return outlet; and an occlusion catheter sized and configured to be slidably positioned through the lumen, the occlusion catheter having an occlusion member, the occlusion member having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; wherein the return lumen is configured to deliver blood via the return outlet at a flow rate sufficient to maintain arterial circulation when the heart is arrested and when at least a portion of the occlusion catheter is positioned therein.
Claim 21
Dependent Claim
61 words
The cardiopulmonary bypass catheter system of claim 17 , comprising: a catheter part at the proximal end of the return cannula in communication with the return lumen and adapted to removably receive the occlusion catheter therein, and a hemostasis valve in the catheter port adapted to seal around the occlusion catheter when the occlusion catheter is positioned in the catheter port.
Claim 22
Dependent Claim
27 words
The cardiopulmonary bypass catheter system of claim 17 , wherein the occlusion catheter has an infusion lumen having an infusion outlet located distal to the occlusion member.
Claim 23
Dependent Claim
21 words
The cardiopulmonary bypass catheter system of claim 17 , wherein the return lumen has an inner diameter of about 5-9 mm.
Claim 24
Dependent Claim
46 words
The cardiopulmonary bypass catheter system of claim 17 , wherein the occlusion catheter is sized such that the occlusion member is located within the ascending aorta between the coronary ostia and the brachiocephalic artery, when the cannula is introduced into an artery peripheral to the aorta.
Claim 25
Dependent Claim
28 words
The cardiopulmonary bypass catheter system of claim 17 , wherein the occlusion member is configured to occlude the aorta when the occlusion member is in the expanded configuration.
Claim 26
Dependent Claim
98 words
A cardiopulmonary bypass catheter system comprising; an occlusion catheter having an occlusion member, the occlusion member having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; a cannula having means for delivering blood at a flow rate sufficient to maintain arterial circulation when the heart is arrested and when at least a portion of the occlusion catheter is disposed within the means; and wherein the occlusion catheter is sized and configured to be slidably positioned through the means.
Claim 27
Dependent Claim
98 words
A cardiopulmonary bypass catheter system comprising; an occlusion catheter having an occlusion member, the occlusion member having a collapsed configuration adapted for introduction through the return lumen and an expanded configuration adapted for occlusion of the ascending aorta between the coronary ostia and the brachiocephalic artery; a cannula having means for delivering blood at a flow rate sufficient to maintain arterial circulation when the heart is arrested and when at least a portion of the occlusion catheter is disposed within the means; and wherein the occlusion catheter is sized and configured to be slidably positioned through the means.
References Cited (Backward Citations)
US3769960A
Cited
US3833003A
Cited
US4117836A
Cited
US4173981A
Cited
US4248224A
Cited
US4276874A
Cited
US4273128A
Cited
US4531936A
Cited
US4527549A
Cited
US4540399A
Cited
US4606347A
Cited
EP0148131A1
Cited
US5275622A
Cited
US4902273A
Cited
US4680029A
Cited
US4592340A
Cited
US4705507A
Cited
US4664125A
Cited
US4697574A
Cited
US4741328A
Cited
US4601713A
Cited
US4785795A
Cited
EP0218275A1
Cited
US4655746A
Cited
US4990139A
Cited
US5024668A
Cited
US4804365A
Cited
US4902272A
Cited
WO1989010155A1
Cited
US4889137A
Cited
US5059178A
Cited
US5011469A
Cited
US5163906A
Cited
US4898577A
Cited
JPH02102665A
Cited
US4877035A
Cited
US4943275A
Cited
US5569201A
Cited
US5176619A
Cited
US5171232A
Cited
US5171232B1
Cited
US4985014A
Cited
WO1991008791A1
Cited
US5209723A
Cited
US5460610A
Cited
US5306249A
Cited
US5116305A
Cited
US5186713A
Cited
US5308320A
Cited
US5820593A
Cited
US5906588A
Cited
US6165162A
Cited
US6475186B1
Cited
US5312344A
Cited
US5219326A
Cited
WO1992017118A1
Cited
US5167628A
Cited
US5533968A
Cited
US5281203A
Cited
US5490837A
Cited
US5125904B1
Cited
US5125904A
Cited
JPH0533736A
Cited
US5554119A
Cited
US5195942A
Cited
US5499996A
Cited
JPH0531194A
Cited
US5254097A
Cited
US5562606A
Cited
US5487730A
Cited
US5458574A
Cited
US5451207A
Cited
US5478309A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2008-03-14 | 2008-09-13 | 2009-03-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2012-03-14 | 2012-09-13 | 2013-03-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2016-03-14 | 2016-09-13 | 2017-03-15 | $7700.00 | Window Closed / Lapsed |