Claims Analysis
Total Claims: 8
Claim 1
Independent Claim
240 words
A directional application device for insertion of a directional spray nozzle into an internal cavity of a human or animal and applying therethrough one or more components to a desired internal site of a human or animal within a desired range of angular directions, the system comprising (a) a source of the components; (b) means for fluid communication integral at a first means end with the source of one or more components and at a second means end with the directional nozzle; and (c) the directional spray nozzle comprising (i) an inner tube of resilient material, the inner tube integral at a first tube end with the second means end and having a nozzle member at a second tube end, the second end being bent to the maximum angle within the desired range of directions, the second end being adapted to avoid piercing tissue in the internal cavity, the inner tube slidably movable within an outer tube, and wherein the inner tube is a multilumen tubing with discrete lumen for two or more components; and (ii) the outer tube of a material more rigid than the inner tube and having an opening at one end to allow the inner tube to slidably project through the opening, whereby the amount of projection of the bent end of the inner tubing through the opening determines the angular direction of the spray nozzle; wherein the one or more components form a fibrin sealant.
Claim 2
Dependent Claim
240 words
A directional application device for insertion of a directional spray nozzle into an internal cavity of a human or animal and applying therethrough one or more components to a desired internal site of a human or animal within a desired range of angular directions, the system comprising (a) a source of the components; (b) means for fluid communication integral at a first means end with the source of one or more components and at a second means end with the directional nozzle; and (c) the directional spray nozzle comprising (i) an inner tube of resilient material, the inner tube integral at a first tube end with the second means end and having a nozzle member at a second tube end, the second end being bent to the maximum angle within the desired range of directions, the second end being adapted to avoid piercing tissue in the internal cavity, the inner tube slidably movable within an outer tube, and wherein the inner tube is a multilumen tubing with discrete lumen for two or more components; and (ii) the outer tube of a material more rigid than the inner tube and having an opening at one end to allow the inner tube to slidably project through the opening, whereby the amount of projection of the bent end of the inner tubing through the opening determines the angular direction of the spray nozzle; wherein the one or more components form a fibrin sealant.
Claim 3
Dependent Claim
40 words
The application device of claim 1 wherein the components comprise a fibrinogen component, carried in one lumen, and a second component, carried in a second lumen, including an enzyme which catalyzes the cleavage of fibrinopeptides A and/or B from fibrinogen.
Claim 4
Dependent Claim
32 words
The application device of claim 1 wherein the components comprise a fibrin monomer component carried in one lumen, and a second component for polymerizing the fibrin monomer carried in a second lumen.
Claim 5
Dependent Claim
17 words
The application device of claim 1 wherein the lumen are about 500 microns or less in diameter.
Claim 6
Dependent Claim
18 words
The application device of claim 1 wherein the nozzle end of the tubing is of a reduced diameter.
Claim 7
Dependent Claim
17 words
The application device of claim 1 wherein the lumen are about 150 microns or less in diameter.
Claim 8
Dependent Claim
45 words
A method for the treatment of spontaneous pneumothorax comprising (a) stapling or suturing an aperture or defect in a lung; (b) using the application device of claim 1 to apply a fibrin sealant to the staple line or suture line; and (c) reinflating the lung.