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US6540716B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Directional endoscopic delivery of material

Assignee: VIVOLUTION AS
•
Filing: 1999-05-06
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Granted: 2003-04-01
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Expires: 2019-05-06
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Abstract

Abstract In accordance with the present invention a directional application system for applying one or more components to a desired internal site in a human or animal within a range of angular directions is disclosed. The present system comprises a source of the components; means for fluid communication integral at a first end with the source of components and at a second end with a directional nozzle; and a directional nozzle comprising an inner tube of resilient material integral at a first end with the second end of the fluid communication means and having a nozzle at a second end, the second end being bent to the maximum angle within the desired range of directions; and an outer tube of a material more rigid than the inner tube and having an opening at one end to allow the inner tube to slidably project through the opening, whereby the amount of projection of the bent end of the inner tubing through the opening determines the angular direction of the nozzle.

Inventors

  • 👤 Niels Erik Holm

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 10:32
CPC Classifications
A; A61; A61B; A61B17/00; A61B17/00491; A61B17/068; A61B17/072; A61B17/07292; A61B2017/00495

Claims Analysis

Total Claims: 8
Claim 1
Independent Claim 240 words
A directional application device for insertion of a directional spray nozzle into an internal cavity of a human or animal and applying therethrough one or more components to a desired internal site of a human or animal within a desired range of angular directions, the system comprising (a) a source of the components; (b) means for fluid communication integral at a first means end with the source of one or more components and at a second means end with the directional nozzle; and (c) the directional spray nozzle comprising (i) an inner tube of resilient material, the inner tube integral at a first tube end with the second means end and having a nozzle member at a second tube end, the second end being bent to the maximum angle within the desired range of directions, the second end being adapted to avoid piercing tissue in the internal cavity, the inner tube slidably movable within an outer tube, and wherein the inner tube is a multilumen tubing with discrete lumen for two or more components; and (ii) the outer tube of a material more rigid than the inner tube and having an opening at one end to allow the inner tube to slidably project through the opening, whereby the amount of projection of the bent end of the inner tubing through the opening determines the angular direction of the spray nozzle; wherein the one or more components form a fibrin sealant.
Claim 2
Dependent Claim 240 words
A directional application device for insertion of a directional spray nozzle into an internal cavity of a human or animal and applying therethrough one or more components to a desired internal site of a human or animal within a desired range of angular directions, the system comprising (a) a source of the components; (b) means for fluid communication integral at a first means end with the source of one or more components and at a second means end with the directional nozzle; and (c) the directional spray nozzle comprising (i) an inner tube of resilient material, the inner tube integral at a first tube end with the second means end and having a nozzle member at a second tube end, the second end being bent to the maximum angle within the desired range of directions, the second end being adapted to avoid piercing tissue in the internal cavity, the inner tube slidably movable within an outer tube, and wherein the inner tube is a multilumen tubing with discrete lumen for two or more components; and (ii) the outer tube of a material more rigid than the inner tube and having an opening at one end to allow the inner tube to slidably project through the opening, whereby the amount of projection of the bent end of the inner tubing through the opening determines the angular direction of the spray nozzle; wherein the one or more components form a fibrin sealant.
Claim 3
Dependent Claim 40 words
The application device of claim 1 wherein the components comprise a fibrinogen component, carried in one lumen, and a second component, carried in a second lumen, including an enzyme which catalyzes the cleavage of fibrinopeptides A and/or B from fibrinogen.
Claim 4
Dependent Claim 32 words
The application device of claim 1 wherein the components comprise a fibrin monomer component carried in one lumen, and a second component for polymerizing the fibrin monomer carried in a second lumen.
Claim 5
Dependent Claim 17 words
The application device of claim 1 wherein the lumen are about 500 microns or less in diameter.
Claim 6
Dependent Claim 18 words
The application device of claim 1 wherein the nozzle end of the tubing is of a reduced diameter.
Claim 7
Dependent Claim 17 words
The application device of claim 1 wherein the lumen are about 150 microns or less in diameter.
Claim 8
Dependent Claim 45 words
A method for the treatment of spontaneous pneumothorax comprising (a) stapling or suturing an aperture or defect in a lung; (b) using the application device of claim 1 to apply a fibrin sealant to the staple line or suture line; and (c) reinflating the lung.

References Cited (Backward Citations)

US4808157A Cited
US5658251A Cited
US5242449A Cited
US5750657A Cited
US5354279A Cited
US5814066A Cited
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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2006-03-31 2006-09-30 2007-04-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2010-03-31 2010-09-30 2011-04-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2014-03-31 2014-09-30 2015-04-01 $7700.00 Window Closed / Lapsed

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