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US6254563B1 Expired / Lapsed US ⏱️ 0.0 years remaining

Perfusion shunt apparatus and method

Assignee: Cardeon Corp
•
Filing: 2000-03-20
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Granted: 2001-07-03
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Expires: 2020-03-20
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Abstract

Abstract A perfusion shunt apparatus and methods are described for isolating and selectively perfusing a segment of a patient's cardiovascular system and for directly circulatory flow around the isolated segment. An aortic perfusion shunt apparatus is configured for deployment within a patient's aortic arch and methods are described for isolating the aortic arch vessels from the aortic lumen, for selectively perfusing the arch vessels with a fluid and for directly blood flow within the aortic lumen through a shunt past the isolated arch vessels. The perfusion shunt apparatus may be mounted on a catheter or cannula for percutaneous introduction or for direct insertion into a circulatory vessel, such as the aorta. The perfusion shunt apparatus has application for protecting a patient from embolic stroke or hypoperfusion during cardiopulmonary bypass or cardiac surgery and also for selectively perfusing the cerebrovascular circulation with oxygenated blood or with neuroprotective fluids in the presence of risk factors, such as head trauma or cardiac insufficiency. The perfusion shunt apparatus will also find application for selective perfusion of other organ systems within the body.

Inventors

  • 👤 John A. Macoviak
  • 👤 Wilfred J. Samson
  • 👤 James J. Leary
  • 👤 Brady D. Esch

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-22 22:27
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1011; A61M1/00; A61M1/36; A61M1/3613; A61M1/3621; A61M1/3653; A61M1/3655; A61M1/3659; A61M2025/1043; A61M2025/1052; A61M2025/1097; A61M2210/00; A61M2210/12; A61M2210/127

Claims Analysis

Total Claims: 62
Claim 1
Independent Claim 139 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable conduit mounted on said catheter shaft, said expandable conduit having an upstream end, a downstream end and a filter mesh material extending therebetween, said expandable conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage; and a downstream sealing member at said downstream end of said expandable conduit for creating a seal between said downstream end of said expandable conduit and the internal wall of the body passage.
Claim 2
Dependent Claim 139 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable conduit mounted on said catheter shaft, said expandable conduit having an upstream end, a downstream end and a filter mesh material extending therebetween, said expandable conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage; and a downstream sealing member at said downstream end of said expandable conduit for creating a seal between said downstream end of said expandable conduit and the internal wall of the body passage.
Claim 3
Dependent Claim 27 words
The catheter apparatus of claim 1 , further comprising a perfusion lumen within said catheter shaft in fluid communication with a space exterior to said expandable conduit.
Claim 4
Dependent Claim 17 words
The catheter apparatus of claim 1 , wherein said upstream sealing member comprises an inflatable toroidal balloon.
Claim 5
Dependent Claim 17 words
The catheter apparatus of claim 3 , wherein said downstream sealing member comprises an inflatable toroidal balloon.
Claim 6
Dependent Claim 28 words
The catheter apparatus of claim 1 , wherein said upstream sealing member comprises an elongated expansion member extendible to expand said upstream end of said expandable shunt conduit.
Claim 7
Dependent Claim 28 words
The catheter apparatus of claim 5 , wherein said downstream sealing member comprises an elongated expansion member extendible to expand said downstream end of said expandable shunt conduit.
Claim 8
Dependent Claim 18 words
The catheter apparatus of claim 1 , wherein said upstream sealing member comprises an external flow control valve.
Claim 9
Dependent Claim 18 words
The catheter apparatus of claim 7 , wherein said downstream sealing member comprises an external flow control valve.
Claim 10
Dependent Claim 20 words
The catheter apparatus of claim 1 , wherein said downstream sealing member comprises a retrograde flow external flow control valve.
Claim 11
Dependent Claim 20 words
The catheter apparatus of claim 9 , wherein said upstream sealing member comprises an antegrade flow external flow control valve.
Claim 12
Dependent Claim 29 words
The catheter apparatus of claim 1 , wherein said expandable shunt conduit further comprises an end wall of porous fabric across said downstream end of said expandable shunt conduit.
Claim 13
Dependent Claim 22 words
The catheter apparatus of claim 1 , further comprising an occlusion member for selectively occluding a vessel proximate said upstream sealing member.
Claim 14
Dependent Claim 25 words
The catheter apparatus of claim 12 , further comprising an infusion lumen within said catheter shaft having an infusion port upstream of said occlusion member.
Claim 15
Dependent Claim 17 words
The catheter apparatus of claim 13 , further comprising a second perfusion lumen within said catheter shaft.
Claim 16
Dependent Claim 24 words
The catheter apparatus of claim 1 , further comprising a tubular sheath sized to fit over said expandable conduit when in said collapsed position.
Claim 17
Dependent Claim 16 words
The catheter apparatus of claim 12 , wherein said occlusion member is an inflatable occlusion balloon.
Claim 18
Dependent Claim 19 words
The catheter apparatus of claim 1 , wherein said catheter shaft is positioned external to said expandable shunt conduit.
Claim 19
Dependent Claim 18 words
The catheter apparatus of claim 1 , wherein said catheter shaft is positioned internal to said expandable conduit.
Claim 20
Dependent Claim 20 words
The catheter apparatus of claim 1 , further comprising an end wall of filter mesh material across said downstream end.
Claim 21
Dependent Claim 110 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable conduit defined by a filter mesh material of varying porosity mounted on said catheter shaft, said expandable conduit having an upstream end and a downstream end, said expandable conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; and an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage.
Claim 22
Dependent Claim 110 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable conduit defined by a filter mesh material of varying porosity mounted on said catheter shaft, said expandable conduit having an upstream end and a downstream end, said expandable conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; and an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage.
Claim 23
Dependent Claim 17 words
The catheter apparatus of claim 20 , wherein said upstream sealing member comprises an inflatable toroidal balloon.
Claim 24
Dependent Claim 27 words
The catheter apparatus of claim 20 , further comprising a perfusion lumen within said catheter shaft in fluid communication with a space exterior to said expandable conduit.
Claim 25
Dependent Claim 18 words
The catheter apparatus of claim 20 , wherein said upstream sealing member comprises an external flow control valve.
Claim 26
Dependent Claim 27 words
The catheter apparatus of claim 20 , wherein said expandable conduit further comprises at least one longitudinal support member attached to a wall of said expandable conduit.
Claim 27
Dependent Claim 27 words
The catheter apparatus of claim 20 , wherein said expandable conduit further comprises an end wall of porous fabric across said downstream end of said expandable conduit.
Claim 28
Dependent Claim 18 words
The catheter apparatus of claim 20 , further comprising an occlusion member for selectively occluding said expandable conduit.
Claim 29
Dependent Claim 25 words
The catheter apparatus of claim 26 , further comprising an infusion lumen within said catheter shaft having an infusion port upstream of said occlusion member.
Claim 30
Dependent Claim 41 words
The catheter apparatus of claim 20 , further comprising a downstream sealing member at said downstream end of said expandable conduit for creating a seal between said downstream end of said expandable conduit and the internal wall of the body passage.
Claim 31
Dependent Claim 17 words
The catheter apparatus of claim 22 , further comprising a second perfusion lumen within said catheter shaft.
Claim 32
Dependent Claim 24 words
The catheter apparatus of claim 20 , further comprising a tubular sheath sized to fit over said expandable conduit when in said collapsed position.
Claim 33
Dependent Claim 16 words
The catheter apparatus of claim 26 , wherein said occlusion member is an inflatable occlusion balloon.
Claim 34
Dependent Claim 18 words
The catheter apparatus of claim 20 , wherein said catheter shaft is positioned external to said expandable conduit.
Claim 35
Dependent Claim 18 words
The catheter apparatus of claim 20 , wherein said catheter shaft is positioned internal to said expandable conduit.
Claim 36
Independent Claim 89 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion catheter into the main vessel; expanding a conduit mounted on said perfusion catheter to open said conduit to fluid flow; sealing an upstream end of said expandable conduit to an internal wall of the main vessel upstream of the branch vessel; perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said expandable conduit; and perfusing the main vessel.
Claim 37
Independent Claim 89 words
A method of perfusing a branch vessel in fluid communication with a main vessel in a body of a patient, comprising: inserting a perfusion catheter into the main vessel; expanding a conduit mounted on said perfusion catheter to open said conduit to fluid flow; sealing an upstream end of said expandable conduit to an internal wall of the main vessel upstream of the branch vessel; perfusing the branch vessel from a perfusion lumen in fluid communication with a space exterior to said expandable conduit; and perfusing the main vessel.
Claim 38
Dependent Claim 27 words
The method of claim 34 , wherein the step of perfusing the main vessel is accomplished by providing a second perfusion lumen extending through said perfusion catheter.
Claim 39
Dependent Claim 16 words
The method of claim 35 , further comprising perfusing a cold fluid to the branch vessel.
Claim 40
Dependent Claim 20 words
The method of claim 34 , wherein the step of perfusing the main vessel is accomplished by a beating heart.
Claim 41
Dependent Claim 15 words
The method of claim 34 , wherein said expandable conduit is comprised of impermeable material.
Claim 42
Dependent Claim 17 words
The method of claim 34 , wherein said expandable conduit is comprised of a porous filter material.
Claim 43
Dependent Claim 21 words
The method of claim 34 , wherein said expandable conduit is comprised of a porous filter material of varying filter porosity.
Claim 44
Dependent Claim 29 words
The method of claim 34 , further comprising sealing a downstream end of said expandable conduit to an internal wall of the main vessel downstream of the branch vessel.
Claim 45
Dependent Claim 37 words
The method of claim 34 , wherein said upstream end of said expandable conduit is sealed to the internal wall of the main vessel by inflating a toroidal balloon at said upstream end of said expandable conduit.
Claim 46
Dependent Claim 37 words
The method of claim 41 , wherein said downstream end of said expandable conduit is sealed to the internal wall of the main vessel by inflating a toroidal balloon at said downstream end of said expandable conduit.
Claim 47
Dependent Claim 39 words
The method of claim 34 , wherein said upstream end of said expandable conduit is sealed to the internal wall of the main vessel by extending an elongated expansion member to expand said upstream end of said expandable conduit.
Claim 48
Dependent Claim 38 words
The method of claim 44 , wherein said downstream end of said conduit is sealed to the internal wall of the main vessel by extending an elongated expansion member to expand said downstream end of said expandable conduit.
Claim 49
Dependent Claim 29 words
The method of claim 34 , wherein said upstream end of said conduit is sealed to the internal wall of the main vessel by an external flow control valve.
Claim 50
Dependent Claim 30 words
The method of claim 46 , wherein said downstream end of said expandable conduit is sealed to the internal wall of the main vessel by an external flow control valve.
Claim 51
Dependent Claim 12 words
The method of claim 34 , further comprising occluding said main vessel.
Claim 52
Dependent Claim 23 words
The method of claim 44 , further comprising infusing fluid into the main vessel upstream of said upstream end of said expandable conduit.
Claim 53
Dependent Claim 28 words
The method of claim 49 further comprising infusing a cardioplegic agent into the patient's aorta upstream of said upstream end of said expandable conduit to induce cardioplegic arrest.
Claim 54
Dependent Claim 116 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable filter shunt apparatus mounted on said catheter shaft, said expandable filter shunt apparatus having an upstream end, a downstream end and a conduit extending therebetween, said conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage; and a filter downstream of said downstream sealing member.
Claim 55
Dependent Claim 116 words
A catheter apparatus for use in a body passage, comprising: a catheter shaft; an expandable filter shunt apparatus mounted on said catheter shaft, said expandable filter shunt apparatus having an upstream end, a downstream end and a conduit extending therebetween, said conduit having a collapsed position in which said expandable conduit is collapsed toward said catheter shaft and an expanded position in which said upstream end of said expandable conduit is open to fluid flow; an upstream sealing member at said upstream end of said expandable conduit for creating a seal between said upstream end of said expandable conduit and an internal wall of the body passage; and a filter downstream of said downstream sealing member.
Claim 56
Dependent Claim 41 words
The catheter apparatus of claim 51 , further comprising a downstream sealing member at said downstream end of said expandable conduit for creating a seal between said downstream end of said expandable conduit and an internal wall of the body passageway.
Claim 57
Dependent Claim 22 words
The catheter apparatus of claim 52 , wherein said filter is positioned between said upstream sealing member and said downstream sealing member.
Claim 58
Dependent Claim 16 words
The catheter apparatus of claim 51 , wherein said filter is positioned downstream of said conduit.
Claim 59
Dependent Claim 16 words
The catheter apparatus of claim 54 , wherein said conduit is adapted for impermeability of fluid.
Claim 60
Dependent Claim 17 words
The aortic catheter of claim 51 , wherein said filter is positioned across said downstream sealing member.
Claim 61
Dependent Claim 27 words
The catheter apparatus of claim 51 , further comprising a perfusion lumen within said catheter shaft in fluid communication with a space exterior to said expandable conduit.
Claim 62
Dependent Claim 30 words
The catheter apparatus of claim 57 , wherein said perfusion lumen is adapted for coupling to a fluid conditioning apparatus to deliver a conditioned fluid to the patient's arch vessels.

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2004-07-02 2005-01-01 2005-07-03 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2008-07-02 2009-01-01 2009-07-03 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2012-07-02 2013-01-01 2013-07-03 $7700.00 Window Closed / Lapsed

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