US6206916B1
Expired / Lapsed
US
⏱️ 0.0 years remaining
Coated intraluminal graft
Assignee: Mirus LLC
•
Filing: 1999-07-29
•
Granted: 2001-03-27
•
Expires: 2019-07-29
Abstract
Abstract An expandable intraluminal graft for use within a body cavity having a tubular shaped member with two ends and a wall surface disposed between the ends. The tubular shaped member has a first diameter to permit intraluminal delivery of the member into a body cavity, and a second expanded diameter. Coated on the surface of the tubular shaped member is a substance that inhibits and/or reduces restenosis, vascular narrowing and/or in-stent restenosis.
Inventors
- 👤 Joseph G. Furst
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 18:30
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/90; A61F2/91; A61F2/915; A61L; A61L31/00; A61L31/08; A61L31/14; A61L31/16; A61F2002/91533; A61F2002/9155; A61F2002/91566; A61F2002/91575; A61F2220/00; A61F2220/0025; A61F2220/005; A61F2220/0058; A61F2230/00; A61F2230/0002; A61F2230/0028; A61F2230/0054; A61L2300/00; A61L2300/40; A61L2300/416; A61L2300/42; A61L2300/60; A61L2300/606
Claims Analysis
Total Claims: 46
Claim 1
Independent Claim
157 words
An intraluminal graft for use within in a body cavity including a geometrically shaped member and a biological agent, said geometrically shaped member having first and second ends and a wall surface disposed between the first and second ends, the wall surface being formed by a plurality of intersecting elongated members, at least some of the elongated members intersecting with one another intermediate the first and second ends of the geometrically shaped member, said geometrically shaped member having a first diameter which permits intraluminal delivery of the geometrically shaped member into a body cavity, and a second expanded diameter, said biological agent being at least partially coated on the surface of said geometrically member, said biological agent including a compound to inhibit or reduce a biological condition selected from the group consisting of restenosis, vascular narrowing, in-stent restenosis and combinations thereof, at least a portion of said biological agent releasably coated on a surface of said graft.
Claim 2
Dependent Claim
157 words
An intraluminal graft for use within in a body cavity including a geometrically shaped member and a biological agent, said geometrically shaped member having first and second ends and a wall surface disposed between the first and second ends, the wall surface being formed by a plurality of intersecting elongated members, at least some of the elongated members intersecting with one another intermediate the first and second ends of the geometrically shaped member, said geometrically shaped member having a first diameter which permits intraluminal delivery of the geometrically shaped member into a body cavity, and a second expanded diameter, said biological agent being at least partially coated on the surface of said geometrically member, said biological agent including a compound to inhibit or reduce a biological condition selected from the group consisting of restenosis, vascular narrowing, in-stent restenosis and combinations thereof, at least a portion of said biological agent releasably coated on a surface of said graft.
Claim 3
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 1 , wherein said biological agent includes a platelet inhibitor.
Claim 4
Dependent Claim
16 words
The expandable intraluminal graft as defined in claim 2 , wherein said platelet inhibitor includes Trapidil.
Claim 5
Dependent Claim
31 words
The expandable intraluminal graft as defined in claim 3 , wherein said body cavity is selected from the group consisting of a body passageway, body duct or a body blood vessel.
Claim 6
Dependent Claim
16 words
The expandable intraluminal graft as defined in claim 4 , wherein said second diameter is variable.
Claim 7
Dependent Claim
35 words
The expandable intraluminal graft of claim 5 , wherein the plurality of elongated members are a plurality of wires, and the wires are fixedly secured to one another where the wires intersect with one another.
Claim 8
Dependent Claim
34 words
The expandable intraluminal graft of claim 5 , wherein the plurality of elongated members are a plurality of thin bars which are fixedly secured to one another where the bars intersect with one another.
Claim 9
Dependent Claim
18 words
The expandable intraluminal graft of claim 5 , wherein said geometrically shaped member includes a plurality of openings.
Claim 10
Dependent Claim
37 words
The expandable intraluminal graft of claim 5 , wherein said graft includes two geometrically shaped members and at least one connector connected between the two geometrically shaped members, said connector allowing transverse bending flexibility of said graft.
Claim 11
Dependent Claim
24 words
The expandable intraluminal graft of claim 5 , wherein said geometrically shaped member includes material to make the geometrically shaped member visible under fluoroscopy.
Claim 12
Dependent Claim
28 words
The expandable intraluminal graft as defined in claim 10 , wherein said geometrically shaped member is at least partially coated with a material that is visible under fluoroscopy.
Claim 13
Dependent Claim
25 words
The expandable intraluminal graft as defined in claim 11 , wherein said material is coated on at least one end of said geometrically shaped member.
Claim 14
Dependent Claim
20 words
The expandable intraluminal graft of claim 12 , wherein said intersecting elongated members are formed by etching and/or laser cutting.
Claim 15
Dependent Claim
34 words
The expandable intraluminal graft of claim 13 , including a mounting substance to be at least partially coated on said graft, said mounting substance at least partially securing said biological agent to said graft.
Claim 16
Dependent Claim
27 words
The expandable intraluminal graft as defined in claim 14 , wherein said mounting substance at least partially delays delivery of said biological agent into said body cavity.
Claim 17
Dependent Claim
36 words
The expandable intraluminal graft as defined in claim 15 , including balloon, said balloon including at least one opening to allow delivery of said biological substance from an interior of said balloon to said body cavity.
Claim 18
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 16 , wherein said biological substance includes said biological agent.
Claim 19
Dependent Claim
34 words
The expandable intraluminal graft of claim 17 , wherein said geometrically shaped member is treated with Gamma or Beta radiation to reduce the vascular narrowing of at least a portion of said body cavity.
Claim 20
Dependent Claim
16 words
The expandable intraluminal graft of claim 18 , wherein said geometrically shaped member is substantially tubular.
Claim 21
Dependent Claim
28 words
The expandable intraluminal graft as defined in claim 5 , wherein said geometrically shaped member is at least partially coated with a material that is visible under fluoroscopy.
Claim 22
Dependent Claim
16 words
The expandable intraluminal graft as defined in claim 2 , wherein said second diameter is variable.
Claim 23
Dependent Claim
34 words
The expandable intraluminal graft of claim 2 , including a mounting substance to be at least partially coated on said graft, said mounting substance at least partially securing said biological agent to said graft.
Claim 24
Dependent Claim
27 words
The expandable intraluminal graft as defined in claim 22 , wherein said mounting substance at least partially delays delivery of said biological agent into said body cavity.
Claim 25
Dependent Claim
36 words
The expandable intraluminal graft as defined in claim 23 , including balloon, said balloon including at least one opening to allow delivery of said biological substance from an interior of said balloon to said body cavity.
Claim 26
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 24 , wherein said biological substance includes said biological agent.
Claim 27
Dependent Claim
36 words
The expandable intraluminal graft as defined in claim 22 , including balloon, said balloon including at least one opening to allow delivery of said biological substance from an interior of said balloon to said body cavity.
Claim 28
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 26 , wherein said biological substance includes said biological agent.
Claim 29
Dependent Claim
36 words
The expandable intraluminal graft as defined in claim 2 , including balloon, said balloon including at least one opening to allow delivery of said biological substance from an interior of said balloon to said body cavity.
Claim 30
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 28 , wherein said biological substance includes said biological agent.
Claim 31
Dependent Claim
31 words
The expandable intraluminal graft as defined in claim 1 , wherein said body cavity is selected from the group consisting of a body passageway, body duct or a body blood vessel.
Claim 32
Dependent Claim
16 words
The expandable intraluminal graft as defined in claim 1 , wherein said second diameter is variable.
Claim 33
Dependent Claim
35 words
The expandable intraluminal graft of claim 1 , wherein the plurality of elongated members are a plurality of wires, and the wires are fixedly secured to one another where the wires intersect with one another.
Claim 34
Dependent Claim
34 words
The expandable intraluminal graft of claim 1 , wherein the plurality of elongated members are a plurality of thin bars which are fixedly secured to one another where the bars intersect with one another.
Claim 35
Dependent Claim
18 words
The expandable intraluminal graft of claim 1 , wherein said geometrically shaped member includes a plurality of openings.
Claim 36
Dependent Claim
37 words
The expandable intraluminal graft of claim 1 , wherein said graft includes two geometrically shaped members and at least one connector connected between the two geometrically shaped members, said connector allowing transverse bending flexibility of said graft.
Claim 37
Dependent Claim
24 words
The expandable intraluminal graft of claim 1 , wherein said geometrically shaped member includes material to make the geometrically shaped member visible under fluoroscopy.
Claim 38
Dependent Claim
28 words
The expandable intraluminal graft as defined in claim 1 , wherein said geometrically shaped member is at least partially coated with a material that is visible under fluoroscopy.
Claim 39
Dependent Claim
25 words
The expandable intraluminal graft as defined in claim 37 , wherein said material is coated on at least one end of said geometrically shaped member.
Claim 40
Dependent Claim
20 words
The expandable intraluminal graft of claim 1 , wherein said intersecting elongated members are formed by etching and/or laser cutting.
Claim 41
Dependent Claim
34 words
The expandable intraluminal graft of claim 1 , including a mounting substance to be at least partially coated on said graft, said mounting substance at least partially securing said biological agent to said graft.
Claim 42
Dependent Claim
27 words
The expandable intraluminal graft as defined in claim 40 , wherein said mounting substance at least partially delays delivery of said biological agent into said body cavity.
Claim 43
Dependent Claim
36 words
The expandable intraluminal graft as defined in claim 1 , including balloon, said balloon including at least one opening to allow delivery of said biological substance from an interior of said balloon to said body cavity.
Claim 44
Dependent Claim
18 words
The expandable intraluminal graft as defined in claim 42 , wherein said biological substance includes said biological agent.
Claim 45
Dependent Claim
34 words
The expandable intraluminal graft of claim 1 , wherein said geometrically shaped member is treated with Gamma or Beta radiation to reduce the vascular narrowing of at least a portion of said body cavity.
Claim 46
Dependent Claim
16 words
The expandable intraluminal graft of claim 1 , wherein said geometrically shaped member is substantially tubular.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2004-03-26 | 2004-09-25 | 2005-03-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2008-03-26 | 2008-09-25 | 2009-03-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2012-03-26 | 2012-09-25 | 2013-03-27 | $7700.00 | Window Closed / Lapsed |