US6159236A
Expired / Lapsed
US
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Expandable treatment device for photodynamic therapy and method of using same
Assignee: Advanced Photodynamic Technologies Inc
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Filing: 1999-01-28
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Granted: 2000-12-12
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Expires: 2019-01-28
Abstract
Abstract The invention relates to a medical device including a tube and expandable member and one or more light sources disposed in an elongated member disposed in the tube. The light sources emit energy for photodynamic therapy through a window to the treatment area. The treatment device may further include a heat and/or light dissipating layer, such as a layer of gold alloy paint, or other light blocking material.
Inventors
- 👤 Merrill A. Biel
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:04
CPC Classifications
A; A61; A61N; A61N5/00; A61N5/06; A61N5/0613; A61N5/062; A61M; A61M25/00; A61M25/10; A61N5/0601; A61B; A61B18/00; A61B18/18; A61B18/20; A61B18/22; A61B2018/2255; A61B2018/2261; A61M2205/00; A61M2205/05; A61M2205/051; A61M2205/58; A61M2205/587; A61N5/0603; A61N2005/0609
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
94 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; and an elongated member providing one or more light sources, the elongated member disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy, and wherein the elongated member is slidably movable within the lumen of the elongated tube.
Claim 2
Dependent Claim
94 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; and an elongated member providing one or more light sources, the elongated member disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy, and wherein the elongated member is slidably movable within the lumen of the elongated tube.
Claim 3
Dependent Claim
25 words
The medical device for photodynamic therapy of claim 1 wherein the energy for photodynamic therapy passes through at least a portion of the medical device.
Claim 4
Dependent Claim
27 words
The medical device for photodynamic therapy of claim 2 wherein the energy for photodynamic therapy passes substantially unrestricted through at least a portion of the medical device.
Claim 5
Dependent Claim
59 words
The medical device for photodynamic therapy of claim 1 wherein the one or more light sources provides light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 .
Claim 6
Dependent Claim
20 words
The medical device for photodynamic therapy of claim 1 wherein the expandable member has a cross-sectional shape that is triangular-like.
Claim 7
Dependent Claim
23 words
The medical device for photodynamic therapy of claim 1 further comprising a layer of gold or gold alloy disposed on the expandable member.
Claim 8
Dependent Claim
24 words
The medical device for photodynamic therapy of claim 1 wherein at least a portion of the elongated member is made of alight diffusing material.
Claim 9
Dependent Claim
40 words
The medical device for photodynamic therapy of claim 1 further comprising a remote light source operatively coupled to the elongated member via at least one of a fiber optic element, a plurality of internal filaments, or one or more VCSELs.
Claim 10
Dependent Claim
23 words
The medical device for photodynamic therapy of claim 1 wherein the elongated member is configured to treat disease in the throat or cheek.
Claim 11
Dependent Claim
18 words
The medical device for photodynamic therapy of claim 1 wherein the expandable member is made of a polymer.
Claim 12
Dependent Claim
35 words
The medical device for photodynamic therapy of claim 1 wherein the tube and the expandable member further including a window for substantially unobstructed delivery of a light emitting source to a portion of a body.
Claim 13
Dependent Claim
114 words
A medical device for photodynamic therapy comprising: a catheter having a balloon disposed thereon, said catheter providing a lumen therewithin for ventilation purposes, the balloon configured to be juxtaposed to one or more body portions; and one or more light sources in light communication with the balloon, the one or more light sources configured to emit energy from the balloon for photodynamic therapy; wherein the one or more light sources provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 to mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 .
Claim 14
Dependent Claim
114 words
A medical device for photodynamic therapy comprising: a catheter having a balloon disposed thereon, said catheter providing a lumen therewithin for ventilation purposes, the balloon configured to be juxtaposed to one or more body portions; and one or more light sources in light communication with the balloon, the one or more light sources configured to emit energy from the balloon for photodynamic therapy; wherein the one or more light sources provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 to mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 .
Claim 15
Independent Claim
195 words
A method of using a light emitting treatment device comprising the steps of: identifying a treatment site in a body; providing a tube having a proximal end, a distal end and a lumen therein, an expandable member being disposed proximate the distal end of the tube; providing an elongated member having one or more light sources, the elongated member being disposed in at least a portion of the tube; providing a control device coupled to the light source to provide at least one of a range of intensity or selective operation of an emitted light energy; disposing the expandable member at the treatment site; positioning the expandable member to direct the light source to emit energy at the treatment site, the one or more light sources configured to provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 ; and activating the light source and the control device for a period of time to emit energy at the treatment site for photodynamic therapy.
Claim 16
Independent Claim
195 words
A method of using a light emitting treatment device comprising the steps of: identifying a treatment site in a body; providing a tube having a proximal end, a distal end and a lumen therein, an expandable member being disposed proximate the distal end of the tube; providing an elongated member having one or more light sources, the elongated member being disposed in at least a portion of the tube; providing a control device coupled to the light source to provide at least one of a range of intensity or selective operation of an emitted light energy; disposing the expandable member at the treatment site; positioning the expandable member to direct the light source to emit energy at the treatment site, the one or more light sources configured to provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 ; and activating the light source and the control device for a period of time to emit energy at the treatment site for photodynamic therapy.
Claim 17
Dependent Claim
94 words
A light emitting treatment device comprising: an expandable member configured to conform to one or more treatment surfaces; one or more light members in light communication with the expandable member; wherein the expandable member and the one or more light members form an assembly and the one or more light members are configured to emit energy from the assembly for photodynamic therapy of the one or more treatment surfaces; and one or more light detectors in light communication with the expandable member and configured to provide monitoring of the one or more treatment surfaces.
Claim 18
Dependent Claim
94 words
A light emitting treatment device comprising: an expandable member configured to conform to one or more treatment surfaces; one or more light members in light communication with the expandable member; wherein the expandable member and the one or more light members form an assembly and the one or more light members are configured to emit energy from the assembly for photodynamic therapy of the one or more treatment surfaces; and one or more light detectors in light communication with the expandable member and configured to provide monitoring of the one or more treatment surfaces.
Claim 19
Dependent Claim
31 words
The light emitting treatment device of claim 14 wherein the monitoring includes at least one of light wavelength (nm), light dosage (joules/cm 2 ), or light dosage rate (mw/cm 2 ).
Claim 20
Dependent Claim
99 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; and an elongated member providing one or more light sources, said elongated member being disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy; and a heat dissipating layer disposed on a portion of either the tube or the elongated member or both.
Claim 21
Dependent Claim
99 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; and an elongated member providing one or more light sources, said elongated member being disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy; and a heat dissipating layer disposed on a portion of either the tube or the elongated member or both.
Claim 22
Dependent Claim
98 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; one or more light sources disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy; and a control device operatively coupled to the light source to provide at least one of a range of intensity or selective operation of the emitted energy.
Claim 23
Dependent Claim
98 words
A medical device for photodynamic therapy comprising: a tube having a proximal end, a distal end and a lumen therein, an expandable member disposed on a distal portion of the tube, the expandable member configured to expand and contract to one or more states; one or more light sources disposed in at least a portion of the tube, the one or more light sources configured to emit energy for photodynamic therapy; and a control device operatively coupled to the light source to provide at least one of a range of intensity or selective operation of the emitted energy.
Claim 24
Dependent Claim
91 words
A light emitting treatment device comprising: an expandable member configured to conform to one or more treatment surfaces, a portion of the expandable member being configured to substantially restrict light energy for photodynamic therapy from exiting the treatment device; and one or more light members in light communication with the expandable member, wherein the expandable member and the one or more light members form an assembly and the one or more light members are configured to emit energy from the assembly for photodynamic therapy of the one or more treatment surfaces.
Claim 25
Dependent Claim
91 words
A light emitting treatment device comprising: an expandable member configured to conform to one or more treatment surfaces, a portion of the expandable member being configured to substantially restrict light energy for photodynamic therapy from exiting the treatment device; and one or more light members in light communication with the expandable member, wherein the expandable member and the one or more light members form an assembly and the one or more light members are configured to emit energy from the assembly for photodynamic therapy of the one or more treatment surfaces.
Claim 26
Independent Claim
135 words
A method of using a light emitting treatment device comprising the steps of: identifying a treatment site in a body; disposing the expandable member at the treatment site; providing a light source in light communication with the expandable member; injecting a drug or dye at the treatment site; positioning the expandable member to direct the light source to emit energy at the treatment site, the one or more light sources configured to provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 ; and activating the light source for a period of time to emit energy at the treatment site for photodynamic therapy.
Claim 27
Independent Claim
135 words
A method of using a light emitting treatment device comprising the steps of: identifying a treatment site in a body; disposing the expandable member at the treatment site; providing a light source in light communication with the expandable member; injecting a drug or dye at the treatment site; positioning the expandable member to direct the light source to emit energy at the treatment site, the one or more light sources configured to provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 ; and activating the light source for a period of time to emit energy at the treatment site for photodynamic therapy.
Claim 28
Dependent Claim
110 words
A medical device for photodynamic therapy comprising: a catheter having a distal end adapted to be placed within a cavity of a body, said catheter providing a lumen for respiratory ventilation purposes of the body; and one or more light sources in light communication with the catheter, the one or more light sources configured to emit energy for photodynamic therapy; wherein the one or more light sources provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 .
Claim 29
Dependent Claim
110 words
A medical device for photodynamic therapy comprising: a catheter having a distal end adapted to be placed within a cavity of a body, said catheter providing a lumen for respiratory ventilation purposes of the body; and one or more light sources in light communication with the catheter, the one or more light sources configured to emit energy for photodynamic therapy; wherein the one or more light sources provide light wavelengths ranging from about 450 nm to about 850 nm; a light dosage rate ranging from about 0 mw/cm 2 to about 150 mw/cm 2 ; and a light dose ranging from 0 J/cm 2 to about 300 J/cm 2 .
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-12-12 | 2004-06-12 | 2004-12-12 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-12-12 | 2008-06-12 | 2008-12-12 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-12-12 | 2012-06-12 | 2012-12-12 | $7700.00 | Window Closed / Lapsed |