US6142952A
Expired / Lapsed
US
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Method and apparatus for detection and diagnosis of airway obstruction degree
Assignee: The University of Texas System
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Filing: 1997-10-29
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Granted: 2000-11-07
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Expires: 2017-10-29
Abstract
Abstract A pressurized breathable gas, preferably air, is supplied to the patient's airways with an interface including a mask and a flexible hose. A selected oscillation component or forced probing signal is applied or superposed on the pressurized breathable gas, preferably with a loudspeaker coupled to a frequency generator. Pressure and flow of the breathable gas in the interface are measured or sampled, preferably using pressure transducers and a pneumotachometer coupled to a personal computer, to obtain pressure and flow data characteristic of the patient's airway. The pressure and flow data are converted to the frequency domain using Fourier transform or cross-power spectrum techniques in the personal computer. A function of the processed pressure and flow data is obtained to determine an index of airway impedance or degree of airway obstruction.
Inventors
- 👤 Khosrow Behbehani
- 👤 John R. Burk
- 👤 Edgar R. Lucas
- 👤 Fu-Chung Yen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 17:08
CPC Classifications
A; A61; A61B; A61B5/00; A61B5/72; A61B5/7235; A61B5/7253; A61B5/08; A61B5/085; A61B5/7203; A61B5/7257
Claims Analysis
Total Claims: 20
Claim 1
Independent Claim
93 words
A method of determining the airway impedance of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio-frequency oscillation component to a pressure of the breathable gas; measuring pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the pressure and flow data to the frequency domain; and obtaining a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
Claim 2
Independent Claim
93 words
A method of determining the airway impedance of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio-frequency oscillation component to a pressure of the breathable gas; measuring pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the pressure and flow data to the frequency domain; and obtaining a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
Claim 3
Dependent Claim
29 words
The method according to claim 1 further comprising processing the measured pressure and flow data to eliminate data having indicia of unreliability after converting it to the frequency domain.
Claim 4
Dependent Claim
37 words
The method according to claim 1 wherein the step of converting the measured pressure and flow data to the frequency domain further comprises the step of: applying a Fourier transform to the measured pressure and flow data.
Claim 5
Dependent Claim
20 words
The method according to claim 1 wherein the oscillation is a multifrequency oscillation applied by a frequency generator and loudspeaker.
Claim 6
Dependent Claim
58 words
The method according to claim 1, wherein the step of obtaining the mathematical function comprises the steps of: dividing the pressure data by the corresponding flow data to obtain an airway impedance or degree of airway obstruction value; and obtaining a mean impedance or degree of airway obstruction from the airway impedance or degree of airway obstruction values.
Claim 7
Dependent Claim
52 words
The method according to claim 2 wherein the processing step comprises: discarding noisy pressure and flow data resulting from a blower supplying breathable gas to the patient's airways through the interface; and applying a coherence function to the pressure and flow data and discarding data with coherence less than a selected threshold.
Claim 8
Independent Claim
113 words
A method of determining the airway impedance or degree of airway obstruction of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio-frequency oscillation component to a pressure of the breathable gas; sampling pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the sampled pressure and flow data to the frequency domain; processing the converted pressure and flow data to eliminate data having indicia of unreliability; and obtaining a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
Claim 9
Independent Claim
113 words
A method of determining the airway impedance or degree of airway obstruction of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio-frequency oscillation component to a pressure of the breathable gas; sampling pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the sampled pressure and flow data to the frequency domain; processing the converted pressure and flow data to eliminate data having indicia of unreliability; and obtaining a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
Claim 10
Dependent Claim
45 words
The method according to claim 7 wherein the step of converting the measured pressure and flow data to the frequency domain further comprises the step of: applying a Fourier transform to the sampled pressure and flow data prior to, processing the pressure and flow data.
Claim 11
Dependent Claim
20 words
The method according to claim 7 wherein the oscillation is a multifrequency oscillation applied by a frequency generator and loudspeaker.
Claim 12
Dependent Claim
58 words
The method according to claim 7, wherein the step of obtaining the mathematical function comprises the steps of: dividing processed pressure data by corresponding processed flow data to obtain an airway impedance or degree of airway obstruction value; and obtaining a mean impedance or degree of airway obstruction from the airway impedance or degree of airway obstruction values.
Claim 13
Dependent Claim
52 words
The method according to claim 7 wherein the processing step comprises: discarding noisy pressure and flow data resulting from a blower supplying breathable gas to the patient's airways through the interface; and applying a coherence function to the pressure and flow data and discarding data with coherence less than a selected threshold.
Claim 14
Independent Claim
128 words
A method of determining the airway impedance or degree of airway obstruction of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio frequency oscillation component of a selected frequency to the breathable gas; measuring pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the pressure and flow data to the frequency domain; discarding converted pressure and flow data that have indicia of inaccuracy; and dividing the pressure data by the corresponding flow data to obtain an airway impedance or degree of airway obstruction value; and obtaining a mean impedance or degree of airway obstruction from the airway impedance or degree of airway obstruction values.
Claim 15
Independent Claim
128 words
A method of determining the airway impedance or degree of airway obstruction of a patient comprising the steps of: supplying breathable gas to the patient's airways with an interface; applying a selected audio frequency oscillation component of a selected frequency to the breathable gas; measuring pressure and flow of the breathable gas in the interface to obtain pressure and flow data characteristic of the patient's airway; converting the pressure and flow data to the frequency domain; discarding converted pressure and flow data that have indicia of inaccuracy; and dividing the pressure data by the corresponding flow data to obtain an airway impedance or degree of airway obstruction value; and obtaining a mean impedance or degree of airway obstruction from the airway impedance or degree of airway obstruction values.
Claim 16
Dependent Claim
45 words
The method according to claim 12 wherein the step of converting the measured pressure and flow data to the frequency domain further comprises the step of: applying a Fourier transform to the measured pressure and flow data prior to processing the pressure and flow data.
Claim 17
Dependent Claim
20 words
The method according to claim 12 wherein the oscillation is a multifrequency oscillation applied by a frequency generator and loudspeaker.
Claim 18
Dependent Claim
52 words
The method according to claim 12 wherein the discarding step comprises: discarding noisy pressure and flow data resulting from a blower supplying breathable gas to the patients airways through the interface; and applying a coherence function to the pressure and flow data and discarding data with coherence less than a selected threshold.
Claim 19
Independent Claim
119 words
An apparatus for determining the airway impedance or degree of airway obstruction of a patient comprising: an interface adapted to be coupled to the patient's airways to supply a breathable gas; means for applying a selected audio-frequency oscillation component to a pressure of the breathable gas; at least one sensor in the interface to measure pressure and flow of the breathable gas in the interface and obtain pressure and flow data characteristic of the patient's airway; and a processor coupled to the sensor to convert the pressure and flow data to the frequency domain and to obtain a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
Claim 20
Independent Claim
119 words
An apparatus for determining the airway impedance or degree of airway obstruction of a patient comprising: an interface adapted to be coupled to the patient's airways to supply a breathable gas; means for applying a selected audio-frequency oscillation component to a pressure of the breathable gas; at least one sensor in the interface to measure pressure and flow of the breathable gas in the interface and obtain pressure and flow data characteristic of the patient's airway; and a processor coupled to the sensor to convert the pressure and flow data to the frequency domain and to obtain a mathematical function of the processed pressure and flow data to determine an index of airway impedance or degree of airway obstruction.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-11-07 | 2004-05-08 | 2004-11-07 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-11-07 | 2008-05-08 | 2008-11-07 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-11-07 | 2012-05-08 | 2012-11-07 | $7700.00 | Window Closed / Lapsed |