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US6069698A Expired / Lapsed US ⏱️ 0.0 years remaining

Optical imaging apparatus which radiates a low coherence light beam onto a test object, receives optical information from light scattered by the object, and constructs therefrom a cross-sectional image of the object

Assignee: Olympus Corp
•
Filing: 1998-08-27
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Granted: 2000-05-30
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Expires: 2018-08-27
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Abstract

Abstract A low coherence beam emitted by a low coherence light source is split into two portions. One portion is transmitted from the outward end of a first single mode fiber via a detachable connector to a beam scanning probe, and then to a biological tissue; and the other is transmitted from an optical coupler placed midway along the light path via a second single mode fiber to a light path modifier. The light path modifier includes a galvanometer mirror to modify the light path length in accordance with a scan range, and a uniaxial stage to adjust the light path length to absorb the variation in lengths of different beam scanning probes. The light path is adjusted by the uniaxial stage such that the beam interference is detected for the scan range, to ensure stable acquisition of tomographic images.

Inventors

  • 👤 Takeshi Ozawa
  • 👤 Mamoru Kaneko
  • 👤 Akihiro Horii
  • 👤 Hitoshi Ueno
  • 👤 Sakae Takehana
  • 👤 Hiroyuki Sangu
  • 👤 Isami Hirao
  • 👤 Hitoshi Mizuno
  • 👤 Toshimasa Kawai
  • 👤 Hiroki Hibino
  • 👤 Hideyuki Adachi
  • 👤 Hironobu Takizawa
  • 👤 Takefumi Uesugi
  • 👤 Masahiro Ohno
  • 👤 Hidemichi Aoki
  • 👤 Jun Hiroya
  • 👤 Katsuichi Imaizumi
  • 👤 Eiji Yasuda
  • 👤 Yoshinao Oaki
  • 👤 Kenji Yoshino

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 12:20
CPC Classifications
G; G01; G01B; G01B9/00; G01B9/02; G01B9/02055; G01B9/02062; G01B9/02067; G01B9/02069; A; A61; A61B; A61B5/00; A61B5/0059; A61B5/0062; A61B5/0066; A61B5/0082; A61B5/0084; G01B9/02049; G01B9/0205; G01B9/02064; G01B9/0209; G01B9/02091; A61B5/0086; G01B2290/00; G01B2290/35; G01B2290/65

Claims Analysis

Total Claims: 38
Claim 1
Independent Claim 209 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample, and to also transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to interfere with each other; a detector which detects the interfering beams; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam, and a second transmission time altering unit to alter the transmission time of the reference beam in accordance with a light path length of the sample beam transmitter.
Claim 2
Dependent Claim 209 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample, and to also transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to interfere with each other; a detector which detects the interfering beams; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam, and a second transmission time altering unit to alter the transmission time of the reference beam in accordance with a light path length of the sample beam transmitter.
Claim 3
Dependent Claim 82 words
The optical imaging apparatus of claim 1, wherein the coupler functions as a low coherence light beam splitter to split the low coherence light beam generated by the light source to form the sample beam and the reference beam; and the low coherence light beam splitter transmits the sample beam via the optical connector to the sample beam transmitter of the optical probe and transmit the reference beam to the first transmission time altering unit and the second transmission time altering unit.
Claim 4
Dependent Claim 118 words
The optical imaging apparatus of claim 2, wherein the low coherence light beam splitter is optically connected to one end of each of a first through a fourth single mode fiber; the other end of the first single mode fiber is optically connected to the light source; the other end of the second single mode fiber is optically connected to the sample beam transmitter; the other end of the third single mode fiber is optically connected to the first transmission time altering unit and the second transmission time altering unit; and the other end of the fourth single mode fiber is optically connected to the detector which detects an interference between the reflected beam and the reference beam.
Claim 5
Dependent Claim 34 words
The optical imaging apparatus of claim 1, further comprising a third transmission time altering unit to alter the transmission time of the reference beam in accordance with the light path of sample beam transmitter.
Claim 6
Dependent Claim 87 words
The optical imaging apparatus of claim 4, wherein the coupler functions as a low coherence light beam splitter to split the low coherence light beam generated by the light source into the sample beam and the reference beam; and the low coherence light beam splitter transmits the sample beam via the optical connector to the sample beam transmitter of the optical probe and transmits the reference beam to the first transmission time altering unit, the second transmission time altering unit, and the third transmission time altering unit.
Claim 7
Dependent Claim 51 words
The optical imaging apparatus of claim 4, wherein the third transmission time altering units includes an optical delay section to alter the transmission time of the reference beam by switching to a particular delay time among a plurality of predetermined delay times in accordance with a given type of optical probe.
Claim 8
Dependent Claim 51 words
The optical imaging apparatus of claim 5, wherein the third transmission time altering unit includes an optical delay section to alter the transmission time of the reference beam by switching to a particular delay time among a plurality of predetermined delay times in accordance with a given type of optical probe.
Claim 9
Dependent Claim 122 words
The optical imaging apparatus of claim 5, wherein the low coherence light beam splitter is optically connected to one end of each of a first through a fourth single mode fibers; the other end of the first single mode fiber is optically connected to the light source; the other end of second single mode fiber is optically connected to the sample beam transmitter; the other end of third single mode fiber is optically connected to the first transmission time altering unit, the second transmission time altering unit, and the third transmission time altering unit; and the other end of fourth single mode fiber is optically connected to the detector which detects an interference fringe between the reflected beam and the reference beam.
Claim 10
Dependent Claim 29 words
The optical imaging apparatus of claim 6, wherein the optical delay section includes a combination of optical switches and a plurality of single mode fibers having different respective lengths.
Claim 11
Dependent Claim 29 words
The optical imaging apparatus of claim 7, wherein the optical delay section includes a combination of optical switches and a plurality of single mode fibers having different respective lengths.
Claim 12
Dependent Claim 27 words
The optical imaging apparatus of claim 1, wherein the first and second transmission time altering units include a galvanometer moving mirror and a uniaxial moving stage, respectively.
Claim 13
Dependent Claim 38 words
The optical imaging apparatus of claim 1, wherein the first transmission time altering unit is a combination of a piezo element and a single mode fiber; and the second transmission time altering unit is a uniaxial moving stage.
Claim 14
Dependent Claim 39 words
The optical imaging apparatus of claim 1, wherein the first transmission time altering unit is a galvanometer moving mirror; and the second transmission time altering unit is a combination of a light reflecting member and a uniaxial moving stage.
Claim 15
Dependent Claim 29 words
The optical imaging apparatus of claim 1, wherein the optical probe is a slender, soft and cylindrical sheath which can be inserted into a forceps channel of an endoscope.
Claim 16
Dependent Claim 47 words
The optical imaging apparatus of claim 14, further comprising: a freely rotatable flexible shaft; and a single mode fiber within the sheath to scan a beam by rotation in the radial direction of the sheath; and a detachable optical connector on the proximal end of the fiber.
Claim 17
Dependent Claim 32 words
The optical imaging apparatus of claim 1, wherein the first transmission time altering unit is capable of rapidly altering the transmission time of the reference beam in accordance with the scan range.
Claim 18
Dependent Claim 34 words
The optical imaging apparatus of claim 1, wherein the first transmission time altering unit is capable of rapidly and periodically altering the transmission time of the reference beam in accordance with the scan range.
Claim 19
Dependent Claim 51 words
The optical imaging apparatus of claim 1, wherein the second transmission time altering unit is so adjustable as to be capable of altering the transmission time of the reference beam within a range defined a target portion of a test object so that tomographic images of that portion may be obtained.
Claim 20
Dependent Claim 208 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample and to transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to form an interference fringe: a detector which detects the interference fringe; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam; and a second transmission time altering unit to alter the transmission time of the reference beam in accordance with a light path length of the sample beam transmitter.
Claim 21
Dependent Claim 208 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample and to transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to form an interference fringe: a detector which detects the interference fringe; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam; and a second transmission time altering unit to alter the transmission time of the reference beam in accordance with a light path length of the sample beam transmitter.
Claim 22
Dependent Claim 81 words
The optical imaging apparatus of claim 19, wherein the coupler functions as a low coherence light beam splitter to split the low coherence light beam generated by the light source into the sample beam and the reference beam; and the low coherence light beam splitter transmits the sample beam via the second transmission time altering unit and the optical connector to the sample beam transmitter of the optical probe and transmits the reference beam to the first transmission time altering unit.
Claim 23
Dependent Claim 111 words
The optical imaging apparatus of claim 20, wherein the low coherence light beam splitter is optically connected to one end of each of a first through a fourth single mode fiber; the other end of the first single mode fiber is optically connected to the light source; the other end of the second single mode fiber is optically connected to the sample beam transmitter; the other end of the third single mode fiber is optically connected to the first transmission time altering unit; and the other end of the fourth single mode fiber is optically connected to the detector which detects an interference between the reflected beam and the reference beam.
Claim 24
Dependent Claim 215 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample and to transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to form an interference fringe; a detector which detects the interference fringe; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam; and a second transmission time altering unit to alter the total transmission time of the low coherence light beam and the reflected beam in accordance with a light path length of the sample beam transmitter.
Claim 25
Dependent Claim 215 words
An optical imaging apparatus comprising: a light source to generate a low coherence light beam; an optical probe which incorporates a sample beam transmitter which includes a single mode fiber to transmit a sample beam containing the low coherence light beam to a test sample and to transmit the sample beam upon being reflected by the test sample; a coupler which is detachably connectable to the optical probe via an optical connector and which allows the reflected sample beam and a reference beam containing the low coherence light beam to form an interference fringe; a detector which detects the interference fringe; an image signal generator to generate image signals on the basis of signals detected by the detector; a first transmission time altering unit which alters the transmission time of the reference beam in accordance with a scan range of the optical probe so that the interference between the reflected beam and the reference beam takes place within the scan range in the axial direction with respect to the optical light paths of the sample beam and the reference beam; and a second transmission time altering unit to alter the total transmission time of the low coherence light beam and the reflected beam in accordance with a light path length of the sample beam transmitter.
Claim 26
Dependent Claim 57 words
The optical imaging apparatus of claim 22 wherein the optical probe a rotatable prism mirror in the tip thereof to reflect the sample beam in radial directions, fluid storing section disposed on the back side of a reflective surface of the prism mirror, and a fluid with a low refractive index stored in the fluid storing section.
Claim 27
Dependent Claim 17 words
The optical imaging apparatus of claim 23, wherein the fluid with a low refractive index is air.
Claim 28
Dependent Claim 106 words
The optical imaging apparatus of claim 1, wherein the optical probe has a sufficiently slender insert so as to be introducible into a test sample body; the probe includes: at least one beam scanning elements affixed to a silicone substrate inserted at the tip of the insert in order to scan the sample beam transmitted via the sample beam transmitter over the test sample; and at least one lenses inserted at the tip of the insert in order to focus the sample beam transmitted via the sample beam transmitter onto the test sample, and to direct the sample beam upon being reflected by the test sample.
Claim 29
Dependent Claim 26 words
The optical imaging apparatus of claim 25, wherein the at least one beam scanning elements are activated through a static electrical force or a magnetic force.
Claim 30
Dependent Claim 36 words
The optical imaging apparatus of claim 25, wherein the at least one beam scanning elements includes two scanning elements to scan the sample beam in a two-dimensional plane tangential to the surface of the test sample.
Claim 31
Dependent Claim 28 words
The optical imaging apparatus of claim 25, wherein the at least one lens is inserted between the sample beam transmitter and the at least one beam scanning elements.
Claim 32
Dependent Claim 27 words
The optical imaging apparatus of claim 25, wherein the at least one lens is inserted between the at least one beam scanning elements and the test sample.
Claim 33
Dependent Claim 66 words
The optical imaging apparatus of claim 29, wherein the at least one lens, the at least one beam scanning elements and the sample beam transmitter are integratively combined to form a beam radiating section, the beam radiating section further including: means to change the position of the beam radiating section in order to alter the distance between the at least one lens and the test sample.
Claim 34
Dependent Claim 144 words
The optical imaging apparatus of claim 1, wherein the optical probe comprises: a slender, soft and cylindrical sheath with a blunt tip which can be introduced into a forceps channel of an endoscope, and which has at least the lateral wall of its tip made of a material which is transmissive to light; a lens which is fixed towards the tip of the sample beam transmitter to focus the sample beam emanating from the sample beam transmitter at a specific position; an ultrasonic motor installed in the interior of the tip of the sheath and including a rotor; a power source to supply electricity to the ultrasonic motor and a controller therefor; light path modifying unit fixed to the rotor of the ultrasonic motor to alter the light path of a light beam passing through the lens through the rotation of the ultrasonic motor.
Claim 35
Dependent Claim 38 words
The optical imaging apparatus of claim 31, wherein the sheath comprises a soft tube which is open at both ends, and a cap which is transmissive to light, the cap being attached to one end of the tube.
Claim 36
Dependent Claim 31 words
The optical imaging apparatus of claim 31, wherein the material of the sheath is formed from a material selected from the group consisting of polymethyl pentane, polyamide, FEP, TPFE or PFA.
Claim 37
Dependent Claim 49 words
The optical imaging apparatus of claim 31, wherein the sheath comprises a soft tube which is open at both ends, a pipe made of a material which is transmissive to light and connected to one end of the tube, and a cap enclosed in one end of the pipe.
Claim 38
Dependent Claim 15 words
The optical imaging apparatus of claim 34, wherein the pipe is made of fused quartz.

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USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-05-30 2003-11-29 2004-05-30 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-05-30 2007-11-29 2008-05-30 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-05-30 2011-11-29 2012-05-30 $7700.00 Window Closed / Lapsed

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