US6041787A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Use of cryoprotective agent compounds during cryosurgery
Assignee: Zeltiq Aesthetics Inc
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Filing: 1998-03-17
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Granted: 2000-03-28
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Expires: 2018-03-17
Abstract
Abstract The invention features an apparatus and method for protecting tissue from freeze damage during cryosurgery. According to the method, a cryoprotective agent is introduced to a tissue to be protected in an amount sufficient to protect the tissue from damage during cryosurgery, and cryosurgery is performed on tissue to be destroyed.
Inventors
- 👤 Boris Rubinsky
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:19
CPC Classifications
A; A01; A01N; A01N1/00; A01N1/10; A01N1/12; A01N1/122; A01N1/125; A61; A61B; A61B18/00; A61B18/02; A61B17/00; A61B17/00234; A61B2017/00238; A61B2017/00274; A61B2018/00315; A61B2018/00547; A61B2018/0231; A61B2018/0262; A61B2018/0268; A61B2018/0275; A61B90/00; A61B90/04; A61B2090/0463; A61B90/36; A61B90/37; A61B2090/374; A61B2090/378; A61B2218/00; A61B2218/001; A61B2218/002
Claims Analysis
Total Claims: 11
Claim 1
Independent Claim
35 words
A method of protecting tissue in-vivo from damage during cryosurgery comprising: introducing a cryoprotective agent to a tissue for protecting the tissue from damage during cryosurgery; and performing cryosurgery of a tissue to be destroyed.
Claim 2
Independent Claim
35 words
A method of protecting tissue in-vivo from damage during cryosurgery comprising: introducing a cryoprotective agent to a tissue for protecting the tissue from damage during cryosurgery; and performing cryosurgery of a tissue to be destroyed.
Claim 3
Dependent Claim
23 words
The method of claim 1 further comprising determining an appropriate concentration of the cryoprotective agent to introduce to the tissue to be protected.
Claim 4
Dependent Claim
20 words
The method of claim 2 wherein determining an appropriate concentration of the cryoprotective agent is by calculation or by experimentation.
Claim 5
Dependent Claim
23 words
The method of claim 1 wherein introducing a cryoprotective agent to a tissue comprises introducing the cryoprotective agent in a gradually increasing amount.
Claim 6
Dependent Claim
47 words
The method of claim 1 wherein introducing a cryoprotective agent to a tissue comprises introducing the cryoprotective agent prior to cryosurgery, and performing cryosurgery of the tissue to be destroyed comprises freezing from an area of the tissue away from a protected region toward the protected region.
Claim 7
Dependent Claim
46 words
The method of claim 1 wherein introducing a cryoprotective agent to a tissue comprises introducing the cryoprotective agent during cryosurgery, and performing cryosurgery of the tissue to be destroyed comprises freezing from an area of the tissue away from a protected region toward the protected region.
Claim 8
Dependent Claim
50 words
The method of claim 1 wherein introducing a cryoprotective agent to a tissue comprises introducing the cryoprotective agent prior to cryosurgery, and performing cryosurgery of the tissue to be destroyed comprises freezing from a region in a protected region toward an area of the tissue away from the protected region.
Claim 9
Dependent Claim
49 words
The method of claim 1 wherein introducing a cryoprotective agent to a tissue comprises introducing the cryoprotective agent during cryosurgery, and performing cryosurgery of the tissue to be destroyed comprises freezing from a region in a protected region toward an area of the tissue away from the protected region.
Claim 10
Dependent Claim
23 words
The method of claim 1 further comprising imaging the process of introducing the cryoprotective agent to a tissue and the process of cryosurgery.
Claim 11
Dependent Claim
17 words
The method of claim 9 wherein imaging comprises imaging with ultrasound imaging or magnetic resonance imaging techniques.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-03-28 | 2003-09-27 | 2004-03-28 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-03-28 | 2007-09-27 | 2008-03-28 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-03-28 | 2011-09-27 | 2012-03-28 | $7700.00 | Window Closed / Lapsed |