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US6037366A Expired / Lapsed US ⏱️ 0.0 years remaining

Composition for creating vascular occlusions

Assignee: Stryker European Operations Holdings LLC
•
Filing: 1998-09-11
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Granted: 2000-03-14
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Expires: 2018-09-11
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Abstract

Abstract A composition including 2-hexyl cyanoacrylate and gold is useful in treating arteriovenous malformations (AVMs) and other body lumens to be blocked.

Inventors

  • 👤 Robert E. Krall
  • 👤 Charles W. Kerber
  • 👤 Kimberly Knox

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:43
CPC Classifications
A; A61; A61L; A61L24/00; A61L24/001; A61K; A61K31/00; A61K31/045; A61K31/05; A61K31/12; A61K31/122; A61K33/00; A61K33/24; A61K33/242; A61L24/04; A61L24/06; C; C09; C09J; C09J4/00; A61L2430/00; A61L2430/36

Claims Analysis

Total Claims: 7
Claim 1
Independent Claim 47 words
A composition for creating therapeutic vascular occlusions in an animal comprising a mixture of: (a) Part 1 comprised of 2-hexyl cyanoacrylate, hydroquinone, p-methoxyphenol and phosphoric acid; and (b) Part 2 comprising gold metal powder, ethyl myristate and a sterilized polymer of 2-hexylcyanoacrylate in weak aqueous bicarbonate solution.
Claim 2
Dependent Claim 47 words
A composition for creating therapeutic vascular occlusions in an animal comprising a mixture of: (a) Part 1 comprised of 2-hexyl cyanoacrylate, hydroquinone, p-methoxyphenol and phosphoric acid; and (b) Part 2 comprising gold metal powder, ethyl myristate and a sterilized polymer of 2-hexylcyanoacrylate in weak aqueous bicarbonate solution.
Claim 3
Dependent Claim 25 words
The composition of claim 1 wherein Part 1 comprises about 100 PPM hydroquinone, 100 PPM p-methoxyphenol, 250 PPM phosphoric acid and the remainder 2-hexyl cyanoacrylate.
Claim 4
Dependent Claim 35 words
The composition of claim 2 wherein Part 2 comprises about 65 percent by weight gold, about 30 percent by weight ethyl myristate and the remainder said sterilized polymer of 2-hexylcyanoacrylate in weak aqueous bicarbonate solution.
Claim 5
Dependent Claim 14 words
The composition of claim 1 wherein Part 2 includes sulfur dioxide as a stabilizer.
Claim 6
Independent Claim 72 words
A method for creating therapeutic vascular occlusions in an animal needing therapeutic vascular occlusion comprising the steps of: (a) Mixing together Part 1 comprised of 2-hexyl cyanoacrylate, hydroquinone, p-methoxyphenol and phosphoric acid with Part 2 comprising gold metal powder, ethyl myristate and a sterilized polymer of 2-hexylcyanoacrylate in weak aqueous bicarbonate solution; and (b) injecting the mixture into a vascular site needing occlusion with the gold metal powder suspended in the mixture.
Claim 7
Independent Claim 72 words
A method for creating therapeutic vascular occlusions in an animal needing therapeutic vascular occlusion comprising the steps of: (a) Mixing together Part 1 comprised of 2-hexyl cyanoacrylate, hydroquinone, p-methoxyphenol and phosphoric acid with Part 2 comprising gold metal powder, ethyl myristate and a sterilized polymer of 2-hexylcyanoacrylate in weak aqueous bicarbonate solution; and (b) injecting the mixture into a vascular site needing occlusion with the gold metal powder suspended in the mixture.

References Cited (Backward Citations)

US4740534A Cited
US5624685A Cited
US5759194A Cited
US5525334A Cited
US5702361A Cited
US5695480A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2003-03-14 2003-09-13 2004-03-14 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2007-03-14 2007-09-13 2008-03-14 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2011-03-14 2011-09-13 2012-03-14 $7700.00 Window Closed / Lapsed

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