US6013053A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Balloon catheter for photodynamic therapy
Assignee: Bausch Health Companies Inc
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Filing: 1996-05-17
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Granted: 2000-01-11
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Expires: 2016-05-17
Abstract
Abstract The present invention provides improved balloon catheter apparatuses for use in therapies requiring delivery of uniform light to a treatment area. The improved apparatus comprises a balloon having a defined treatment window where the window is delineated using a reflective material. The apparatus may further include a fiber optic cable that terminates in a diffusion tip where the diffusion tip is longer than the treatment window. The present invention further provides improved therapeutic methods that use the improved balloon catheters of the present invention.
Inventors
- 👤 Bob Bower
- 👤 Mike Stonefield
- 👤 Joseph Yan
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:11
CPC Classifications
A; A61; A61B; A61B18/00; A61N; A61N5/00; A61N5/06; A61N5/0613; A61N5/062; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61N5/0601; A61B17/00; A61B2017/00017; A61B2017/00022; A61B2017/00057; A61B17/22; A61B2017/22051; A61B2017/22057; A61B2017/22058; A61B2017/22059; A61B2018/2255; A61B2018/2261
Claims Analysis
Total Claims: 29
Claim 1
Independent Claim
118 words
A balloon catheter apparatus for providing irradiation to a defined treatment area, said apparatus comprising: i) a clear central channel into which a fiber optic cable can be inserted; and ii) an outer sleeve, for use in inflating a balloon, both the sleeve and balloon have a proximal end and a distal end, said sleeve is positioned within the inflatable balloon proximate to said distal end; wherein the surface of said balloon is coated on both ends with a coated reflective material so as to define a treatment window therebetween and the coated reflective material, which defines the treatment window, collects and reflects light through the treatment window, thereby enhancing uniformity of light distribution in the treatment area.
Claim 2
Dependent Claim
118 words
A balloon catheter apparatus for providing irradiation to a defined treatment area, said apparatus comprising: i) a clear central channel into which a fiber optic cable can be inserted; and ii) an outer sleeve, for use in inflating a balloon, both the sleeve and balloon have a proximal end and a distal end, said sleeve is positioned within the inflatable balloon proximate to said distal end; wherein the surface of said balloon is coated on both ends with a coated reflective material so as to define a treatment window therebetween and the coated reflective material, which defines the treatment window, collects and reflects light through the treatment window, thereby enhancing uniformity of light distribution in the treatment area.
Claim 3
Dependent Claim
19 words
The apparatus of claim 1, wherein said treatment window is from about 1 cm to 20 cm in length.
Claim 4
Dependent Claim
16 words
The apparatus of claim 1 wherein the treatment window in said balloon is cylindrical in shape.
Claim 5
Dependent Claim
33 words
The apparatus of claim 3 wherein said cylindrical treatment window is from about 3 mm to about 200 mm in length and from about 1 mm to 100 mm in diameter when inflated.
Claim 6
Dependent Claim
23 words
The apparatus of claim 1 wherein said reflective coating is selected from the group consisting of TiO 2 , aluminum, silver and gold.
Claim 7
Dependent Claim
66 words
The apparatus of claim 1 further comprising a fiber optic cable that terminates in a diffuser, said diffuser being positioned within the treatment window so that it extends beyond each side of said treatment window and results in light being more uniformly distributed on the treatment area and wherein said fiber optic cable is adapted so as to be provided with light from a light source.
Claim 8
Dependent Claim
12 words
The apparatus of claim 6, wherein said diffuser is a cylindrical diffuser.
Claim 9
Dependent Claim
23 words
The apparatus of claim 7 wherein said diffuser extends about 0.3 cm to about 5 cm beyond each side of said treatment window.
Claim 10
Dependent Claim
14 words
The apparatus of claim 1 wherein said balloon is made of high density polyurethane.
Claim 11
Dependent Claim
11 words
The apparatus of claim 1 wherein said treatment window is transparent.
Claim 12
Dependent Claim
11 words
The apparatus of claim 1 wherein said treatment window is translucent.
Claim 13
Dependent Claim
19 words
The apparatus of claim 1 further comprising one or more optical sensors attached to the wall of said balloon.
Claim 14
Dependent Claim
41 words
The apparatus of claim 1 further comprising in said central channel a fiber optic cable that terminates in a diffuser disposed within said treatment window, wherein said fiber optic cable is adapted to be provided with light from a light source.
Claim 15
Dependent Claim
20 words
The apparatus of claim 13, wherein a laser diode of less than about 1.5W is used as a light source.
Claim 16
Dependent Claim
40 words
A method for administering light to a defined target area in a subject, which method comprises inserting into said subject the balloon catheter as defined in claim 13, and introducing light from a light source into said fiber optic cable.
Claim 17
Dependent Claim
19 words
The apparatus of claim 1 wherein the reflective or scattering material is coated on the outside of the balloon.
Claim 18
Dependent Claim
19 words
The apparatus of claim 1 wherein the reflective or scattering material is coated on the inside of the balloon.
Claim 19
Dependent Claim
143 words
A balloon catheter apparatus for providing irradiation to a defined area, said apparatus comprising (i) a clear central channel into which a fiber optic cable can be inserted; and (ii) an outer sleeve for use in inflating a balloon, the sleeve and balloon have a proximal end and a distal end, said sleeve containing the inflatable balloon proximal to said distal end; and wherein said balloon contains a treatment window between the ends defined by a coating on the interior walls of said balloon; and (iii) inserted into said clear central channel, a fiber optic cable terminating in a diffuser positioned within said treatment window, which cable is adapted to be provided with light from a light source, wherein said diffuser extends sufficiently beyond each side of the treatment window to enhance the efficiency and uniformity of light distribution in the treatment area.
Claim 20
Dependent Claim
143 words
A balloon catheter apparatus for providing irradiation to a defined area, said apparatus comprising (i) a clear central channel into which a fiber optic cable can be inserted; and (ii) an outer sleeve for use in inflating a balloon, the sleeve and balloon have a proximal end and a distal end, said sleeve containing the inflatable balloon proximal to said distal end; and wherein said balloon contains a treatment window between the ends defined by a coating on the interior walls of said balloon; and (iii) inserted into said clear central channel, a fiber optic cable terminating in a diffuser positioned within said treatment window, which cable is adapted to be provided with light from a light source, wherein said diffuser extends sufficiently beyond each side of the treatment window to enhance the efficiency and uniformity of light distribution in the treatment area.
Claim 21
Dependent Claim
20 words
The apparatus of claim 18, wherein a laser diode of less than about 1.5W is used as a light source.
Claim 22
Dependent Claim
50 words
An improved method for administering light to a defined target area wherein a balloon catheter coupled to a light source is inserted into a subject and light is emitted from said light source into said catheter said improvement comprising the use of a balloon catheter as defined in claim 18.
Claim 23
Dependent Claim
40 words
A method for administering light to a defined target area in a subject, which method comprises inserting into said subject the balloon catheter as defined in claim 18, and introducing light from a light source into said fiber optic cable.
Claim 24
Dependent Claim
29 words
An improved balloon catheter apparatus containing a defined treatment window for providing irradiation to a defined area, said improvement comprising using a reflective material to define the treatment window.
Claim 25
Dependent Claim
29 words
An improved balloon catheter apparatus containing a defined treatment window for providing irradiation to a defined area, said improvement comprising using a reflective material to define the treatment window.
Claim 26
Dependent Claim
50 words
An improved method for administering light to a defined target area wherein a balloon catheter coupled to a light source is inserted into a subject and light is emitted from said light source into said catheter said improvement comprising the use of a balloon catheter as defined in claim 13.
Claim 27
Dependent Claim
150 words
A balloon catheter apparatus for providing irradiation to a defined treatment area, said apparatus comprising: a multi-channel sleeve with a first clear central lumen into which a fiber optic cable can be inserted; and one or more second lumens for use in inflating a balloon, both the tubing and balloon having a proximal end and a distal end, said tubing being attached to the inflatable balloon proximate to said distal end of said balloon; wherein 1) the ends of the balloon contain a reflective or a scattering material, which defines the treatment window, collects and reflects and/or scatters light through the treatment window, thereby enhancing uniformity of light distribution in the treatment area and 2) wherein said multi-channel sleeve comprises: i) a sleeve, having a clear central channel into which a fiber optic cable can be inserted; and ii) at least one additional channel, for use in inflating a balloon.
Claim 28
Dependent Claim
150 words
A balloon catheter apparatus for providing irradiation to a defined treatment area, said apparatus comprising: a multi-channel sleeve with a first clear central lumen into which a fiber optic cable can be inserted; and one or more second lumens for use in inflating a balloon, both the tubing and balloon having a proximal end and a distal end, said tubing being attached to the inflatable balloon proximate to said distal end of said balloon; wherein 1) the ends of the balloon contain a reflective or a scattering material, which defines the treatment window, collects and reflects and/or scatters light through the treatment window, thereby enhancing uniformity of light distribution in the treatment area and 2) wherein said multi-channel sleeve comprises: i) a sleeve, having a clear central channel into which a fiber optic cable can be inserted; and ii) at least one additional channel, for use in inflating a balloon.
Claim 29
Dependent Claim
19 words
The apparatus of claim 24 wherein the reflective or scattering material is coated on the outside of the balloon.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2003-01-10 | 2003-07-12 | 2004-01-11 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2007-01-10 | 2007-07-12 | 2008-01-11 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2011-01-10 | 2011-07-12 | 2012-01-11 | $7700.00 | Window Closed / Lapsed |