US5753708A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Derivatives of 4-hydroxybutyric acid
Assignee: Individual
•
Filing: 1996-04-23
•
Granted: 1998-05-19
•
Expires: 2016-04-23
Abstract
Abstract The invention describes new salts and amides of 4-hydroxybutyric acid with the aim of improving the pharmacological and therapeutic properties of 4-hydroxybutyric acid.
Inventors
- 👤 Gernot Koehler
- 👤 Anita Koehler
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 13:01
CPC Classifications
C; C07; C07C; C07C215/00; C07C215/02; C07C215/04; C07C215/06; C07C215/10; A; A61; A61P; A61P23/00; A61P23/02; A61P25/00; A61P25/02; A61P25/20; A61P25/26; A61P25/30; C07C235/00; C07C235/02; C07C235/04; C07C235/08; C07C59/00; C07C59/01
Claims Analysis
Total Claims: 10
Claim 1
Independent Claim
29 words
A parenteral preparation for narcosis in anaesthesia consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
Claim 2
Dependent Claim
29 words
A parenteral preparation for narcosis in anaesthesia consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
Claim 3
Dependent Claim
31 words
A parenteral preparation for sleep induction or long-term sedation consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
Claim 4
Dependent Claim
31 words
A parenteral preparation for sleep induction or long-term sedation consisting essentially of an aqueous solution of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide.
Claim 5
Dependent Claim
30 words
An oral preparation for alcohol withdrawal therapy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Claim 6
Dependent Claim
30 words
An oral preparation for alcohol withdrawal therapy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Claim 7
Dependent Claim
32 words
An oral preparation for therapy of cataplexy or narcolepsy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Claim 8
Dependent Claim
32 words
An oral preparation for therapy of cataplexy or narcolepsy consisting essentially of at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Claim 9
Dependent Claim
33 words
An oral preparation for therapy of sleep disturbance syndrome consisting essentially of comprising at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
Claim 10
Dependent Claim
33 words
An oral preparation for therapy of sleep disturbance syndrome consisting essentially of comprising at least one compound selected from the group consisting of N-2-hydroxyethyl-4-hydroxybutyramide, N-2-hydroxyethyl-N-methyl-4-hydroxybutyramide, N,N-bis-(2-hydroxyethyl)-4-hydroxybutyramide and N-(1-hydroxymethyl-2-hydroxyethyl)-4-hydroxybutyramide and a pharmaceutically effective carrier.
References Cited (Backward Citations)
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2001-05-18 | 2001-11-17 | 2002-05-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2005-05-18 | 2005-11-17 | 2006-05-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2009-05-18 | 2009-11-17 | 2010-05-19 | $7700.00 | Window Closed / Lapsed |