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US5655548A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for treatment of ischemic heart disease by providing transvenous myocardial perfusion

Assignee: Medtronic Vascular Inc
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Filing: 1996-09-16
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Granted: 1997-08-12
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Expires: 2016-09-16
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Abstract

Abstract Methods are provided for use in open surgical and transluminal methods for supplying long-term retrograde perfusion of the myocardium via a conduit disposed between the left ventricle and the coronary sinus. In a first method, an opening is formed between the left ventricle and the coronary sinus, and the coronary ostium is partially occluded using a stent that prevents the pressure in the coronary sinus from exceeding a predetermined value. In an alternative method, a first end of a conduit is inserted transeptally through the right atrium and obliquely into the posterior septal endocardium of the left ventricle via the posterior pyramidal space, while a second end of the conduit is inserted into the coronary sinus via the coronary ostium. A pressure-limiting valve is included in the conduit. In either method, the outlet from the left ventricle to the coronary sinus may include a one-way valve to prevent backflow from the coronary sinus into the left ventricle during cardiac diastole.

Inventors

  • 👤 James A. Nelson
  • 👤 Ascher Shmulewitz

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 09:14
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/94; A61B; A61B17/00; A61B17/32; A61B17/320016; A61F2/02; A61F2/04; A61F2/06; A61F2/064; A61F2/24; A61F2/2493; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/00247; A61B2017/00252; A61B18/00; A61B2018/00315; A61B2018/00345; A61B2018/00351; A61B2018/00392; A61F2220/00; A61F2220/0008; A61F2220/0016; A61M; A61M25/00; A61M25/0021; A61M25/0067; A61M25/0074; A61M25/0075

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 89 words
A method of treating ischemic heart disease by providing long-term retrograde transvenous myocardial perfusion, the method comprising steps of: creating a conduit between a patient's left ventricle and coronary sinus, so that blood flows through the conduit from the left ventricle to the coronary sinus during cardiac systole; partially occluding the patient's coronary ostium; and limiting a peak pressure attained within the coronary sinus by venting blood received from the left ventricle into the patient's right atrium when the pressure attained within the coronary sinus exceeds a predetermined value.
Claim 2
Independent Claim 89 words
A method of treating ischemic heart disease by providing long-term retrograde transvenous myocardial perfusion, the method comprising steps of: creating a conduit between a patient's left ventricle and coronary sinus, so that blood flows through the conduit from the left ventricle to the coronary sinus during cardiac systole; partially occluding the patient's coronary ostium; and limiting a peak pressure attained within the coronary sinus by venting blood received from the left ventricle into the patient's right atrium when the pressure attained within the coronary sinus exceeds a predetermined value.
Claim 3
Dependent Claim 62 words
The method as defined in claim 1 wherein the step of creating the conduit comprises steps of: inserting a cutting instrument into the coronary sinus via the coronary ostium; and actuating the cutting instrument to bore through a wall of the coronary sinus, through the patient's epicardium, myocardium and endocardium to create a passageway between the left ventricle and the coronary sinus.
Claim 4
Dependent Claim 40 words
The method as defined in claim 2 wherein the step of creating the conduit further comprises steps of: transluminally inserting a catheter carrying a stent into the coronary sinus via the coronary ostium; and deploying the stent in the passageway.
Claim 5
Dependent Claim 32 words
The method as defined in claim 3 further comprising a step of providing a stent having a one-way valve that prevents backflow of blood from the coronary sinus to the left ventricle.
Claim 6
Dependent Claim 57 words
The method as defined in claim 1 wherein the step of limiting a peak pressure comprises steps of: providing a plug having a pressure sensitive valve, the pressure sensitive valve opening when the pressure exceeds the predetermined value; transluminally inserting a catheter carrying the plug into the coronary ostium; and deploying the plug in the coronary ostium.
Claim 7
Dependent Claim 90 words
The method as defined in claim 1 wherein the step of creating the conduit comprises steps of: providing a device having a first end, a second end, and a lumen extending therebetween; inserting a cutting instrument into the right atrium; actuating the cutting instrument to create a passageway through the right atrial endocardium and into the left ventricular septal endocardium, the passageway extending through the posterior pyramidal space; implanting the first end of the device in the passageway; and implanting the second end of the device into the coronary ostium.
Claim 8
Dependent Claim 43 words
The method as defined in claim 6 wherein the step of creating the conduit further comprises steps of: inserting the device into a catheter; transluminally inserting the catheter into the right atrium; and deploying the first end of the device in the passageway.
Claim 9
Dependent Claim 50 words
The method as defined in claim 7 wherein the step of creating the conduit further comprises steps of: transluminally inserting a second catheter into the right atrium; capturing the second end of the device with the second catheter; and implanting the second end of the device in the coronary ostium.
Claim 10
Dependent Claim 36 words
The method as defined in claim 6 wherein the step of providing a device further comprises providing a device having a one-way valve that prevents backflow of blood from the coronary sinus to the left ventricle.
Claim 11
Dependent Claim 44 words
The method as defined in claim 6 wherein the step of limiting a peak pressure comprises a step of: during the step of providing a device, providing a pressure sensitive valve that opens into the right atrium when the pressure exceeds the predetermined value.

References Cited (Backward Citations)

US5380316A Cited
US5389096A Cited
US5287861A Cited
US5409019A Cited
US5429144A Cited
US5549581A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 2000-08-11 2001-02-10 2001-08-12 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2004-08-11 2005-02-10 2005-08-12 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2008-08-11 2009-02-10 2009-08-12 $7700.00 Window Closed / Lapsed

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