US5596005A
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Omega-deoxy-azasugars
Assignee: Scripps Research Institute
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Filing: 1993-12-23
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Granted: 1997-01-21
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Expires: 2013-12-23
Abstract
Abstract Omega-deoxy-azapyranose compounds, processes of making and using the same are disclosed, as are a process of making omega-deoxy-azafuranose compounds.
Inventors
- 👤 Chi-Huey Wong
- 👤 Tetsuya Kajimoto
- 👤 Kun-Chin Liu
- 👤 Lihren Chen
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:14
CPC Classifications
C; C07; C07C; C07C247/00; C07C247/02; C07C247/04; C07C311/00; C07C311/15; C07C311/16; C07C311/18; C07D; C07D211/00; C07D211/04; C07D211/06; C07D211/36; C07D211/40; C07D211/44; C07D211/46; C07D211/56; C07D211/92; C07D211/94; C07F; C07F7/00; C07F7/02; C07F7/08; C07F7/0803; C07F7/081; C07F7/0812; C07F9/00; C07F9/02; C07F9/06; C07F9/08; C07F9/09; C07F9/091; C12; C12N; C12N9/00; C12N9/10; C12N9/12; C12N9/1241; C12P; C12P19/00; C12P19/04; C12P19/18; C12P19/26
Claims Analysis
Total Claims: 12
Claim 1
Independent Claim
21 words
A 1,6-dideoxy-azapyranose of the formula ##STR26## wherein R 1 is selected from the group consisting of hydroxyl, N-acetyl, fluoro and ethoxy.
Claim 2
Dependent Claim
21 words
A 1,6-dideoxy-azapyranose of the formula ##STR26## wherein R 1 is selected from the group consisting of hydroxyl, N-acetyl, fluoro and ethoxy.
Claim 3
Dependent Claim
6 words
A 1,6-dideoxy-azapyranose of the formula ##STR27##
Claim 4
Dependent Claim
6 words
A 1,6-dideoxy-azapyranose of the formula ##STR27##
Claim 5
Dependent Claim
6 words
A dideoxy-azapyranose having the formula ##STR28##
Claim 6
Dependent Claim
6 words
A dideoxy-azapyranose having the formula ##STR28##
Claim 7
Dependent Claim
6 words
A compound having the formula ##STR29##
Claim 8
Dependent Claim
6 words
A compound having the formula ##STR29##
Claim 9
Dependent Claim
137 words
An omega-deoxy-azapyranose of the formula I: ##STR30## wherein R is hydroxymethyl; R 1 is hydrogen, hydroxyl, C 1 -C 4 alkoxy, halide, or NR 6 R 7 where R 6 is hydrogen or C 1 -C 4 alkyl and R 7 is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 acyl or NR 6 R 7 together form a cyclic imido group that contains 4-8 carbon atoms; R 2 is hydrogen or hydroxyl; R 3 is hydrogen or hydroxyl; R 4 is methyl; R 5 is selected from the group consisting of hydrogen, C 1 -C 12 alkyl, C 7 -C 10 aralkyl and C 1 -C 12 acyl, or >N--R 5 is a C 1 -C 12 alkyl or C 7 -C 10 aralkyl N-oxide; and the deoxy-azapyranose contains at least two hydroxyl groups.
Claim 10
Dependent Claim
137 words
An omega-deoxy-azapyranose of the formula I: ##STR30## wherein R is hydroxymethyl; R 1 is hydrogen, hydroxyl, C 1 -C 4 alkoxy, halide, or NR 6 R 7 where R 6 is hydrogen or C 1 -C 4 alkyl and R 7 is hydrogen, C 1 -C 4 alkyl, C 1 -C 4 acyl or NR 6 R 7 together form a cyclic imido group that contains 4-8 carbon atoms; R 2 is hydrogen or hydroxyl; R 3 is hydrogen or hydroxyl; R 4 is methyl; R 5 is selected from the group consisting of hydrogen, C 1 -C 12 alkyl, C 7 -C 10 aralkyl and C 1 -C 12 acyl, or >N--R 5 is a C 1 -C 12 alkyl or C 7 -C 10 aralkyl N-oxide; and the deoxy-azapyranose contains at least two hydroxyl groups.
Claim 11
Dependent Claim
16 words
The compound according to claim 5 having a formula selected from the group consisting of ##STR31##
Claim 12
Dependent Claim
25 words
A composition comprising an aqueous medium having dispersed therein a glycosidase-inhibiting amount of a deoxy-azapyranose of any of claims 1, 2, 3, 5 or 6.
References Cited (Backward Citations)
No citation records indexed.
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 2000-01-21 | 2000-07-22 | 2001-01-21 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2004-01-21 | 2004-07-22 | 2005-01-21 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2008-01-21 | 2008-07-22 | 2009-01-21 | $7700.00 | Window Closed / Lapsed |