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US5510370A Expired / Lapsed US ⏱️ 0.0 years remaining

Parathyroid hormone and raloxifene for increasing bone mass

Assignee: Eli Lilly and Co
•
Filing: 1995-03-06
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Granted: 1996-04-23
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Expires: 2015-03-06
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Abstract

Abstract The present invention includes a method for increasing bone mass in a subject by administration of PTH and raloxifene. Another aspect of the invention is a method for treating bone loss in a subject by administration of PTH and raloxifene. The invention further provides for a composition of PTH and raloxifene for increasing bone mass in a subject. Another aspect of the invention is a composition of PTH and raloxifene for treatment of bone loss in a subject.

Inventors

  • 👤 Janet M. Hock

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 03:43
CPC Classifications
A; A61; A61K; A61K38/00; A61K38/16; A61K38/17; A61K38/22; A61K38/29; A61K31/00; A61K31/33; A61K31/395; A61K31/435; A61K31/44; A61K31/445; A61K31/4523; A61K31/4535; A61P; A61P19/00; A61P19/08; A61P19/10; A61P3/00; A61P43/00; A61K2300/00

Claims Analysis

Total Claims: 16
Claim 1
Independent Claim 27 words
A method for increasing bone mass in a subject, comprising administering a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene, to the subject.
Claim 2
Independent Claim 27 words
A method for increasing bone mass in a subject, comprising administering a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene, to the subject.
Claim 3
Dependent Claim 10 words
The method of claim 1, wherein the subject is human.
Claim 4
Dependent Claim 10 words
The method of claim 1, wherein the administration is concurrent.
Claim 5
Dependent Claim 12 words
The method of claim 1, wherein PTH and raloxifene are administered simultaneously.
Claim 6
Independent Claim 27 words
A method for treating bone loss in a subject, comprising administering a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene to the subject.
Claim 7
Independent Claim 27 words
A method for treating bone loss in a subject, comprising administering a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene to the subject.
Claim 8
Dependent Claim 10 words
The method of claim 5 wherein the subject is human.
Claim 9
Dependent Claim 10 words
The method of claim 5 wherein the administration is concurrent.
Claim 10
Dependent Claim 12 words
The method of claim 5, wherein PTH and raloxifene are administered simultaneously.
Claim 11
Dependent Claim 28 words
A composition for increasing bone mass in a subject, comprising a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene in a pharmaceutically acceptable excipient.
Claim 12
Dependent Claim 28 words
A composition for increasing bone mass in a subject, comprising a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene in a pharmaceutically acceptable excipient.
Claim 13
Dependent Claim 17 words
The composition of claim 9 wherein the molar ratio of PTH to raloxifene is 10:1 to 1:10.
Claim 14
Dependent Claim 28 words
A composition for treating bone loss in a subject, comprising a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene in a pharmaceutically acceptable excipient.
Claim 15
Dependent Claim 28 words
A composition for treating bone loss in a subject, comprising a pharmaceutically effective dose of PTH and a pharmaceutically effective dose of raloxifene in a pharmaceutically acceptable excipient.
Claim 16
Dependent Claim 17 words
The composition of claim 11 wherein the molar ratio of PTH to raloxifene is 10:1 to 1:10.

References Cited (Backward Citations)

US4133814A Cited
US4418068A Cited
US5118667A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1999-04-23 1999-10-23 2000-04-23 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2003-04-23 2003-10-23 2004-04-23 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2007-04-23 2007-10-23 2008-04-23 $7700.00 Window Closed / Lapsed

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