US5441966A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Methods of inhibiting Turner's syndrome
Assignee: Eli Lilly and Co
•
Filing: 1993-12-21
•
Granted: 1995-08-15
•
Expires: 2013-12-21
Abstract
Abstract A method of inhibiting Turner's Syndrome comprising administering to a human in need thereof an effective amount of a compound having the formula <IMAGE> (I) wherein R1 and R3 are independently hydrogen, -CH3, <IMAGE> wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Inventors
- 👤 Jeffrey A. Dodge
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:51
CPC Classifications
A; A61; A61K; A61K31/00; A61K31/33; A61K31/395; A61K31/40; A61K31/38; A61K31/4025; A61K31/435; A61K31/44; A61K31/445; A61K31/4523; A61K31/4535; A61P; A61P13/00; A61P13/02; A61P15/00; A61K31/55; C; C07; C07D; C07D409/00; C07D409/02; C07D409/10
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
64 words
A method of inhibiting Turner's Syndrome comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R 1 and R 3 are independently hydrogen, --CH 3 , ##STR6## wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamethylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claim 2
Independent Claim
64 words
A method of inhibiting Turner's Syndrome comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R 1 and R 3 are independently hydrogen, --CH 3 , ##STR6## wherein Ar is optionally substituted phenyl; R 2 is selected from the group consisting of pyrrolidine, hexamethylenemino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.
Claim 3
Dependent Claim
13 words
The method of claim 1 wherein said compound is the hydrochloride salt thereof.
Claim 4
Dependent Claim
14 words
The method of claim 1 wherein said compound is ##STR7## or its hydrochloride salt,
Claim 5
Dependent Claim
16 words
The method of claim 1 wherein the human is also administered an androgen or growth hormone,
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1998-08-14 | 1999-02-13 | 1999-08-15 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2002-08-14 | 2003-02-13 | 2003-08-15 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2006-08-14 | 2007-02-13 | 2007-08-15 | $7700.00 | Window Closed / Lapsed |