US5360616A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Injectable pharmaceutical composition
Assignee: Aplicaciones Farmaceuticas SA de CV
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Filing: 1991-06-13
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Granted: 1994-11-01
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Expires: 2011-06-13
Abstract
Abstract Formulations of programmed-release medicinal products intended for parenteral administration by injection, comprising calibrated solid microspheres (1 to 300 microns) of active substances. Provided in this form, steroids (for example progesterone and 17- beta -estradiol) may constitute injectable contraceptives, and the action of drugs having an approximatively 24 hours lasting effect may be regulated and extended.
Inventors
- 👤 Josue Garza Flores
- 👤 Laura P. Laiseca Soto
- 👤 Jose Guillen Pichardo
- 👤 Juan Angeles Uribe
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 16:29
CPC Classifications
A; A61; A61K; A61K9/00; A61K9/14; A61K9/16; A61K9/1682; A61K9/1694; A61K9/1688; A61P; A61P3/00; A61P3/02; A61P43/00
Claims Analysis
Total Claims: 6
Claim 1
Independent Claim
44 words
Solid, non-porous microspheres of a diameter between 1 and 300 μm, wherein said microspheres consist of an injectable steroid and wherein said microspheres are obtained by spraying said steroid in the melted state to form droplets and rapidly freezing said droplets in a gas.
Claim 2
Dependent Claim
44 words
Solid, non-porous microspheres of a diameter between 1 and 300 μm, wherein said microspheres consist of an injectable steroid and wherein said microspheres are obtained by spraying said steroid in the melted state to form droplets and rapidly freezing said droplets in a gas.
Claim 3
Dependent Claim
20 words
The solid, non-porous microspheres according to claim 1, wherein the diameter of said microspheres is between 5 and 100 μm.
Claim 4
Dependent Claim
31 words
The solid, non-porous microspheres according to claim 2, wherein the melting point of said steroid is greater than 60 ° C. and wherein said steroid is thermostable above the melting point.
Claim 5
Dependent Claim
13 words
The solid, non-porous microspheres according to claim 1, wherein said steroid is progesterone.
Claim 6
Dependent Claim
13 words
The solid, non-porous microspheres according to claim 1, wherein said steroid is 17-β-estradiol.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-10-31 | 1998-05-02 | 1998-11-01 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-10-31 | 2002-05-02 | 2002-11-01 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-10-31 | 2006-05-02 | 2006-11-01 | $7700.00 | Window Closed / Lapsed |