US5349947A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
Assignee: Individual
•
Filing: 1993-07-15
•
Granted: 1994-09-27
•
Expires: 2013-07-15
Abstract
Abstract A powder inhaler and process are provided for aerosolizing finely powdered or pulverized medication and a gas provided in a pillow or blister-type container of extremely thin elastic suitable plastic construction. The pillow is compressed between an anvil with a conical depression and a confronting conical piston. The conical depression has a small orifice at its apex, and the periphery of the pillow is restrained so that compression between the conical pillow and the conical depression produces explosive rupture of the pillow and exit of the gas and medication at a very high speed up to supersonic through said orifice. Medication particle clumps are very efficiently separated into separate particles, and the gas/medication exiting from the orifice are conveyed through a very small area linear or curved tube to a dispersal chamber or directly to a patient, movement through the tube producing a shearing action further enhancing separation of aggregated particles of powder medication.
Inventors
- 👤 Michael T. Newhouse
- 👤 W. Douglas Baines
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:11
CPC Classifications
A; A61; A61M; A61M15/00; A61M15/0028; A61M15/0001; A61M15/0013; A61M15/0015; A61M15/0018; A61M15/003; A61M15/0031; A61M15/0045; A61M15/0046; A61M15/005; A61M15/0086; B; B65; B65D; B65D83/00; B65D83/06; A61M2202/00; A61M2202/06; A61M2202/064; A61M2205/00; A61M2205/60; A61M2205/6063; A61M2205/6081
Claims Analysis
Total Claims: 27
Claim 1
Independent Claim
229 words
A powder inhaler assembly for dispersing medication, said assembly not using a propellant, said assembly comprising a pillow containing a dose of powdered medication and gas, said pillow constructed of plastic means for explosively discharging the powdered medication and gas from inside said pillow comprising a housing having a dispersal chamber, means providing an exit from said chamber for transporting dispersed medication to a patient, a support in said housing, said support having a depression of predetermined shape and having a maximum transverse dimension of predetermined size, said depression having an outlet orifice which is small relative to said predetermined size, a piston positioned opposite to said depression and having a surface confronting said depression which at least in part conforms to said depression, means for moving said piston towards said depression to compress a medication pillow therein, means associated with said piston and said depression for providing peripheral support to a medication pillow, said pillow being completely restrained except for said orifice, the gas in said pillow compressing responsive to continued movement of said piston toward said depression and resulting in explosive rupturing of said pillow, said dose and gas exploding and deaggregating into said orifice and through said orifice, for inhalation by a patient, wherein said exit means includes a conduit means from said orifice to said dispersal chamber for transmission of aerosolized medication to a patient.
Claim 2
Dependent Claim
229 words
A powder inhaler assembly for dispersing medication, said assembly not using a propellant, said assembly comprising a pillow containing a dose of powdered medication and gas, said pillow constructed of plastic means for explosively discharging the powdered medication and gas from inside said pillow comprising a housing having a dispersal chamber, means providing an exit from said chamber for transporting dispersed medication to a patient, a support in said housing, said support having a depression of predetermined shape and having a maximum transverse dimension of predetermined size, said depression having an outlet orifice which is small relative to said predetermined size, a piston positioned opposite to said depression and having a surface confronting said depression which at least in part conforms to said depression, means for moving said piston towards said depression to compress a medication pillow therein, means associated with said piston and said depression for providing peripheral support to a medication pillow, said pillow being completely restrained except for said orifice, the gas in said pillow compressing responsive to continued movement of said piston toward said depression and resulting in explosive rupturing of said pillow, said dose and gas exploding and deaggregating into said orifice and through said orifice, for inhalation by a patient, wherein said exit means includes a conduit means from said orifice to said dispersal chamber for transmission of aerosolized medication to a patient.
Claim 3
Dependent Claim
33 words
A powder inhaler assembly as set forth in claim 1 wherein said depression is at least in part conical, said conical depression having an apex, said outlet orifice being located at said apex.
Claim 4
Dependent Claim
17 words
A powder inhaler assembly as set forth in claim 2 wherein said peripheral restraint comprises a cylinder.
Claim 5
Dependent Claim
17 words
A powder inhaler assembly as set forth in claim 1 wherein said peripheral restraint comprises a cylinder.
Claim 6
Dependent Claim
67 words
A powder inhaler assembly as set forth in claim 1 wherein said peripheral support comprises conformation of one of said depression and said piston which is initially nonconforming to the other such that radially outward portions of said piston and said depression engage before radially inner portions, at least one of said piston and said depression subsequently deforming to conform to the shape of the other thereof.
Claim 7
Dependent Claim
25 words
A powder inhaler assembly as set forth in claim 5 wherein said depression is conical having an apex, said orifice being disposed at said apex.
Claim 8
Dependent Claim
58 words
A powder inhaler assembly as set forth in claim 6 wherein the radially outer portion of said depression has a predetermined angle, and a radially inner portion thereof has a steeper angle, said piston being constructed of deformable material, and a radially inner portion of said piston deforms to conform to said radially inner portion of said depression.
Claim 9
Dependent Claim
57 words
A powder inhaler assembly as set forth in claim 6 wherein said conical depression has a predetermined angle, said piston has a radially inner portion conforming to said conical depression and having the same predetermined angle, a radially outer portion of said piston having a different angle, said piston being deformable to conform to said conical depression.
Claim 10
Dependent Claim
20 words
A powder inhaler assembly as set forth in claim 8 wherein the radially outer portion of said piston is flat.
Claim 11
Dependent Claim
34 words
A powder inhaler assembly as set forth in claim 9 wherein said conduit means has a small cross section relative to said predetermined size to provide shearing forces enhancing deagregation of said powdered medication.
Claim 12
Dependent Claim
16 words
A powder inhaler assembly as set forth in claim 10 wherein said conduit means is curved.
Claim 13
Dependent Claim
17 words
A powder inhaler assembly as set forth in claim 10 wherein said conduit means comprises a spiral.
Claim 14
Dependent Claim
192 words
Apparatus for dispersing of medication, said apparatus not using a propellant, said apparatus comprising, a pillow containing powdered medication and a gas together in said pillow said pillow being of plastic construction; said apparatus further comprising means for explosively discharging the powdered medication and gas from within said pillow comprising a base, a support on said base, said support having a depression of predetermined shape and having a maximum transverse dimension of predetermined size, said depression having an outlet orifice which is small relative to said predetermined size, a piston positioned opposite to said depression and having a surface confronting said depression which at least in part conforms to said depression, means for moving said piston towards said depression to compress said medication pillow positioned therein, means associated with said piston and depression for providing peripheral support to said medication pillow, said pillow being completely restrained except for said orifice, the gas in said pillow compressing responsive to continued movement of said piston toward said depression and resulting in explosive rupturing of said pillow, said dose of powdered medication and gas exploding and deaggregating into said orifice for inhalation by a patient.
Claim 15
Dependent Claim
192 words
Apparatus for dispersing of medication, said apparatus not using a propellant, said apparatus comprising, a pillow containing powdered medication and a gas together in said pillow said pillow being of plastic construction; said apparatus further comprising means for explosively discharging the powdered medication and gas from within said pillow comprising a base, a support on said base, said support having a depression of predetermined shape and having a maximum transverse dimension of predetermined size, said depression having an outlet orifice which is small relative to said predetermined size, a piston positioned opposite to said depression and having a surface confronting said depression which at least in part conforms to said depression, means for moving said piston towards said depression to compress said medication pillow positioned therein, means associated with said piston and depression for providing peripheral support to said medication pillow, said pillow being completely restrained except for said orifice, the gas in said pillow compressing responsive to continued movement of said piston toward said depression and resulting in explosive rupturing of said pillow, said dose of powdered medication and gas exploding and deaggregating into said orifice for inhalation by a patient.
Claim 16
Dependent Claim
32 words
Apparatus as set forth in claim 13 and further including a conduit of small cross section relative to said predetermined size leading from said orifice for enhancing of deaggregation by shearing action.
Claim 17
Dependent Claim
14 words
Apparatus as set forth in claim 14 wherein said peripheral restraint comprises a cylinder.
Claim 18
Dependent Claim
14 words
Apparatus as set forth in claim 13 wherein said peripheral restraint comprises a cylinder.
Claim 19
Dependent Claim
64 words
Apparatus as set forth in claim 13 wherein said peripheral support comprises conformation of one of said depression and said piston which is initially nonconforming to the other such that radially outward portions of said piston and said depression engage before radially inner portions, at least one of said piston and said depression subsequently deforming to conform to the shape of the other thereof.
Claim 20
Dependent Claim
22 words
Apparatus as set forth in claim 17 wherein said depression is conical having an apex, said orifice being disposed at said apex.
Claim 21
Dependent Claim
55 words
Apparatus as set forth in claim 18 wherein the radially outer portion of said depression has a predetermined angle, and a radially inner portion thereof has a steeper angle, said piston being constructed of deformable material, and a radially inner portion of said piston deforms to conform to said radially inner portion of said depression.
Claim 22
Dependent Claim
54 words
Apparatus as set forth in claim 18 wherein said conical depression has a predetermined angle, said piston has a radially inner portion conforming to said conical depression and having the same predetermined angle, a radially outer portion of said piston having a different angle, said piston being deformable to conform to said conical depression.
Claim 23
Dependent Claim
17 words
Apparatus as set forth in claim 20 wherein the radially outer portion of said piston is flat.
Claim 24
Dependent Claim
80 words
A process for propellant free dispersing of powder medication, said process comprising the steps of providing a plastic pillow containing powder medication and a gas, completely surrounding said pillow except for a very small area relative to the size of said pillow, explosively rupturing said pillow at said small area by compressing said pillow and the gas within said pillow while so surrounded and thereby deaggregating said powder medication, and delivering said deaggregated powder medication to a patient for inhalation.
Claim 25
Dependent Claim
80 words
A process for propellant free dispersing of powder medication, said process comprising the steps of providing a plastic pillow containing powder medication and a gas, completely surrounding said pillow except for a very small area relative to the size of said pillow, explosively rupturing said pillow at said small area by compressing said pillow and the gas within said pillow while so surrounded and thereby deaggregating said powder medication, and delivering said deaggregated powder medication to a patient for inhalation.
Claim 26
Dependent Claim
40 words
The process as set forth in claim 22 and further including the step of guiding gas and medication from said very small area along a path of small cross section to produce a shearing action further separating clumps of medication.
Claim 27
Dependent Claim
34 words
The process as set forth in claim 23 wherein the step of guiding gas and medication along a path of small cross section comprises moving said powder medication and gas along a curved path.
References Cited (Backward Citations)
GB190707525A
Cited
US2549303A
Cited
US3367535A
Cited
GB2142246A
Cited
US4905866A
Cited
EP0469814A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-09-26 | 1998-03-28 | 1998-09-27 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-09-26 | 2002-03-28 | 2002-09-27 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-09-26 | 2006-03-28 | 2006-09-27 | $7700.00 | Window Closed / Lapsed |