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US5348553A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for promoting blood vessel healing

Assignee: Individual
•
Filing: 1991-12-18
•
Granted: 1994-09-20
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Expires: 2011-12-18
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Abstract

Abstract A method of repairing a blood vessel having a narrowed portion therein comprising the steps of expanding the narrowed portion of the blood vessel so that the diameter of the blood vessel after expansion is enlarged; and then maintaining an electronegative potential on the interior surface of the expanded narrowed portion of the blood vessel to at least as great as any electropositive potential generated by the blood vessel as a result of the injury to the blood vessel caused by the expansion thereof.

Inventors

  • 👤 Douglass G. Whitney

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 11:05
CPC Classifications
A; A61; A61F; A61F2/00; A61F2/82; A61F2/86; A61F2/95; A61F2/958; A61M; A61M25/00; A61M25/10; A61M25/104; A61N; A61N1/00; A61N1/02; A61N1/04; A61N1/05; A61N1/056; A61B; A61B17/00; A61B17/22; A61B2017/22001; A61B2017/22038; A61F2/848; A61F2002/8486; A61F2220/00; A61F2220/0008; A61F2220/0016

Claims Analysis

Total Claims: 11
Claim 1
Independent Claim 84 words
A method of repairing a blood vessel having a narrowed portion therein comprising the steps of: (a) expanding the narrowed portion of the blood vessel so that the diameter of the blood vessel after expansion is enlarged; (b) maintaining an electronegative potential on the interior surface of the expanded narrowed portion of the blood vessel to at least as great as any electropositive potential generated by the blood vessel as a result of an injury to the blood vessel caused by the expansion thereof.
Claim 2
Independent Claim 84 words
A method of repairing a blood vessel having a narrowed portion therein comprising the steps of: (a) expanding the narrowed portion of the blood vessel so that the diameter of the blood vessel after expansion is enlarged; (b) maintaining an electronegative potential on the interior surface of the expanded narrowed portion of the blood vessel to at least as great as any electropositive potential generated by the blood vessel as a result of an injury to the blood vessel caused by the expansion thereof.
Claim 3
Dependent Claim 58 words
The method of claim 1 wherein step (a) comprises the substeps of: (a1) inserting a balloon catheter into the narrowed portion of the blood vessel until a collapsed balloon on the catheter is in alignment with the narrowed portion of the blood vessel; and (a2) inflating the balloon to forcibly enlarge the narrowed portion of the blood vessel.
Claim 4
Dependent Claim 56 words
The method of claim 1 further comprising the step of: (c) locating a stent in the expanded narrowed portion of the blood vessel with the stent in contact with the interior surface of the expanded narrowed portion of the blood vessel; and maintaining the electronegative potential on the stent to at least offset said electropositive potential.
Claim 5
Dependent Claim 47 words
The method of claim 1 further comprising the step of: (c) locating intimal cells on the interior of the expanded narrowed portion of the blood vessel to promote the formation of surface lining of intimal cells on the interior surface while the electronegative potential is maintained thereon.
Claim 6
Dependent Claim 96 words
The method of claim 1 further comprising the steps of: (c) locating an electrically conductive stent in the expanded narrowed portion of the blood vessel with the stent in contact with the interior surface of the expanded narrowed portion of the blood vessel; and maintaining the electronegative potential on the stent to at least offset said electropositive potential; and (d) locating intimal cells on the interior of the expanded narrowed portion of the blood vessel to promote the formation of surface lining of intimal cells on the interior surface while the electronegative potential is maintained thereon.
Claim 7
Dependent Claim 141 words
The method of claim 1 wherein step (a) comprises the substeps of: (a1) locating a stent over a collapsed balloon of a balloon catheter where the stent has an initial diameter smaller than the narrowed portion of the blood vessel; (a2) inserting the balloon catheter into the narrowed portion of the blood vessel until the collapsed balloon on the catheter is in registration with the narrowed portion of the blood vessel while holding the stent in position over the collapsed balloon of the catheter; and (a2) inflating the balloon to forcibly enlarge the narrowed portion of the blood vessel and enlarge the stent into contact with the interior of the expanded narrowed portion of the blood vessel to help maintain the blood vessel enlarged; and wherein step (b) further includes the substep of (b1) maintaining the electronegative potential on the stent.
Claim 8
Dependent Claim 29 words
The method of claim 1 wherein step (b) further comprises maintaining a current density of about 50 milliamps per square centimeter on the interior surface of the blood vessel.
Claim 9
Independent Claim 129 words
A method of repairing a blood vessel having a narrowed portion therein comprising the steps of: (a) detecting an electrical potential on the interior surface of the narrowed portion of the blood vessel; (a) expanding the narrowed portion of the blood vessel so that the diameter of the blood vessel after expansion is enlarged; and (c) applying an electronegative potential to the interior surface of the expanded narrowed portion of the blood vessel until the electrical potential on the interior surface is about equal to the detected electrical potential on the interior of the narrowed portion of the blood vessel to at least as great as any electropositive potential generated by the blood vessel as a result of an injury to the blood vessel caused by the expansion thereof.
Claim 10
Independent Claim 129 words
A method of repairing a blood vessel having a narrowed portion therein comprising the steps of: (a) detecting an electrical potential on the interior surface of the narrowed portion of the blood vessel; (a) expanding the narrowed portion of the blood vessel so that the diameter of the blood vessel after expansion is enlarged; and (c) applying an electronegative potential to the interior surface of the expanded narrowed portion of the blood vessel until the electrical potential on the interior surface is about equal to the detected electrical potential on the interior of the narrowed portion of the blood vessel to at least as great as any electropositive potential generated by the blood vessel as a result of an injury to the blood vessel caused by the expansion thereof.
Claim 11
Dependent Claim 29 words
The method of claim 8 wherein step (c) further comprises maintaining a current density of about 50 milliamps per square centimeter on the interior surface of the blood vessel.

References Cited (Backward Citations)

US4733665A Cited
US4733665B1 Cited
US4733665C2 Cited
US5078736A Cited
US5178618A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1997-09-19 1998-03-21 1998-09-20 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2001-09-19 2002-03-21 2002-09-20 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2005-09-19 2006-03-21 2006-09-20 $7700.00 Window Closed / Lapsed

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