US5338840A
Expired / Lapsed
US
⏱️ 0.0 years remaining
DNA encoding glioma-derived growth factor having vascular endothelial cell growth promoting activity
Assignee: Merck Sharp & Dohme LLC
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Filing: 1992-05-27
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Granted: 1994-08-16
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Expires: 2012-05-27
Abstract
Abstract Glioma-derived growth factor is purified from the culture media used to maintain mammalian glioma cells. The protein stimulates mitogenesis of mammalian vascular endothelial cells and is useful for the promotion of vascular development and repair. This unique growth factor is also useful in the promotion of tissue repair.
Inventors
- 👤 Marvin L. Bayne
- 👤 Kenneth A. Thomas, Jr.
- 👤 Gregory L. Conn
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 14:49
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; A; A61; A61P; A61P17/00; A61P43/00; A61K; A61K38/00
Claims Analysis
Total Claims: 2
Claim 1
Independent Claim
19 words
A purified and isolated DNA molecule encoding glioma-derived growth factor having the nucleotide sequence as shown in the FIGURE.
Claim 2
Dependent Claim
19 words
A purified and isolated DNA molecule encoding glioma-derived growth factor having the nucleotide sequence as shown in the FIGURE.
References Cited (Backward Citations)
US4456550A
Cited
US4665037A
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EP0370989A2
Cited
WO1990013649A1
Cited
WO1991002058A1
Cited
US5194596A
Cited
US5219739A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-08-15 | 1998-02-14 | 1998-08-16 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-08-15 | 2002-02-14 | 2002-08-16 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-08-15 | 2006-02-14 | 2006-08-16 | $7700.00 | Window Closed / Lapsed |