Patent EP0001929A2 successfully refreshed from Google Patents.
US5332671A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Production of vascular endothelial cell growth factor and DNA encoding same
Assignee: Genentech Inc
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Filing: 1989-08-04
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Granted: 1994-07-26
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Expires: 2009-08-04
Abstract
Abstract DNA isolates coding for a vascular endothelial cell growth factor may be used to produce the protein via recombinant expression systems. Such protein is useful therapeutically to treat conditions in which a selective action on the vascular endothelial cells, in the absence of excessive connective tissue proliferation, is desirable.
Inventors
- 👤 Napoleone Ferrara
- 👤 David W.-H. Leung
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:47
CPC Classifications
C; C07; C07K; C07K14/00; C07K14/435; C07K14/52; A; A61; A61P; A61P9/00; A61K; A61K38/00
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
25 words
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 2 for bovine mature vascular endothelial cell growth factor.
Claim 2
Dependent Claim
25 words
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 2 for bovine mature vascular endothelial cell growth factor.
Claim 3
Dependent Claim
26 words
An expression vector comprising the DNA sequence of claim 1 operably linked to control sequences that are operable in a host cell transformed with the vector.
Claim 4
Dependent Claim
9 words
The vector of claim 2 that is a plasmid.
Claim 5
Dependent Claim
11 words
A host cell transformed with the expression vector of claim 2.
Claim 6
Dependent Claim
9 words
The host cell of claim 4 that is eukaryotic.
Claim 7
Dependent Claim
9 words
The host cell of claim 5 that is mammalian.
Claim 8
Dependent Claim
25 words
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 10 for human mature vascular endothelial cell growth factor.
Claim 9
Dependent Claim
25 words
An isolated DNA sequence comprising a nucleotide sequence encoding the amino acid sequence shown in FIG. 10 for human mature vascular endothelial cell growth factor.
Claim 10
Dependent Claim
26 words
An expression vector comprising the DNA sequence of claim 7 operably linked to control sequences that are operable in a host cell transformed with the vector.
Claim 11
Dependent Claim
9 words
The vector of claim 7 that is a plasmid.
Claim 12
Dependent Claim
11 words
A host cell transformed with the expression vector of claim 8.
Claim 13
Dependent Claim
9 words
The host cell of claim 10 that is eukaryotic.
Claim 14
Dependent Claim
9 words
The host cell of claim 10 that is mammalian.
References Cited (Backward Citations)
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Cited
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Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-07-25 | 1998-01-24 | 1998-07-26 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-07-25 | 2002-01-24 | 2002-07-26 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-07-25 | 2006-01-24 | 2006-07-26 | $7700.00 | Window Closed / Lapsed |