US5304214A
Expired / Lapsed
US
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Transurethral ablation catheter
Assignee: Cook Medical Technologies LLC
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Filing: 1992-01-21
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Granted: 1994-04-19
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Expires: 2012-01-21
Abstract
Abstract A catheter, system, and method for selectively ablating prostatic tissue about the prostatic urethra. The catheter includes an elongated member having distal, proximal, and intermediate portions, the intermediate portion being shaped and sized for intimate contact with the prostatic urethra. The distal and proximal portions of the catheter include fixation and cooling balloons having an annular recess therein for positioning the internal and external sphincters therein and for maintaining the longitudinal position of the catheter in the prostatic urethra. A thermally conducted, heat-emitting element is positioned in the intermediate portion for producing a thermally conductive heat distribution to ablate the prostatic tissue. The catheter also includes irrigation and aspiration passageways therein for communicating with the interior of the distal and proximal cooling balloons. A circulating pump of the ablation system circulates coolant through the balloons to maintain the temperature of the sphincters below an injurious temperature. Sensors are positioned about the heat-emitting element as well as in the cooling balloons for supplying information to the controller of the system. The controller in response to the temperature information and the energy supplied to the heat-emitting element controls the supply of energy to the catheter as well as the pump circulating the coolant.
Inventors
- 👤 John A. DeFord
- 👤 Joseph F. Ely
- 👤 Neal E. Fearnot
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 00:42
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/10; A61M25/1002; A61B; A61B18/00; A61B18/04; A61B18/08; A61B18/082; A61M25/01; A61M25/02; A61M25/04; A61B17/00; A61B2017/00017; A61B2017/00022; A61B2017/00084; A61B2017/00101; A61B17/00234; A61B2017/00238; A61B2017/00274; A61B2018/00005; A61B2018/00011; A61B2018/00023; A61B2018/00315; A61B2018/00547; A61B2018/00982; A61M25/1011
Claims Analysis
Total Claims: 44
Claim 1
Independent Claim
121 words
A transurethral ablation catheter for ablating prostatic tissue about a prostatic urethra positioned between internal and external sphincters, comprising: an elongated member having a distal portion, a proximal portion, and an intermediate portion, said intermediate portion being positioned between said distal and proximal portions and shaped and sized for intimate contact with said prostatic urethra, at least one of said distal and proximal portions including fixation means positionable about at least one of said internal and external sphincters, respectively, for maintaining longitudinally said intermediate portion in said prostatic urethra; and a thermally conductive heat-emitting element positioned in said intermediate portion and responsive to energy supplied thereto for producing a predetermined thermally conductive heat distribution in said tissue to ablate said tissue.
Claim 2
Dependent Claim
121 words
A transurethral ablation catheter for ablating prostatic tissue about a prostatic urethra positioned between internal and external sphincters, comprising: an elongated member having a distal portion, a proximal portion, and an intermediate portion, said intermediate portion being positioned between said distal and proximal portions and shaped and sized for intimate contact with said prostatic urethra, at least one of said distal and proximal portions including fixation means positionable about at least one of said internal and external sphincters, respectively, for maintaining longitudinally said intermediate portion in said prostatic urethra; and a thermally conductive heat-emitting element positioned in said intermediate portion and responsive to energy supplied thereto for producing a predetermined thermally conductive heat distribution in said tissue to ablate said tissue.
Claim 3
Dependent Claim
26 words
The ablation catheter of claim 1 wherein said fixation means comprises a first inflatable balloon positioned about at least one of said distal and proximal portions.
Claim 4
Dependent Claim
30 words
The ablation catheter of claim 2 wherein said first inflatable balloon when inflated includes a first annular recess for positioning at least one of said internal and external sphincters therein.
Claim 5
Dependent Claim
26 words
The ablation catheter of claim 2 wherein said elongated member further includes supply means communicating with said first inflatable balloon for inflating said first inflatable balloon.
Claim 6
Dependent Claim
22 words
The ablation catheter of claim 4 wherein said supply means further includes means for circulating a coolant in said first inflatable balloon.
Claim 7
Dependent Claim
19 words
The ablation catheter of claim 5 further comprising a temperature sensor means for measuring the temperature of said coolant.
Claim 8
Dependent Claim
25 words
The ablation catheter of claim 2 wherein said fixation means comprises a second inflatable balloon positioned about the other of said distal and proximal portions.
Claim 9
Dependent Claim
32 words
The ablation catheter of claim 7 wherein said elongated member further includes supply means communicating with said first and said second inflatable balloons for inflating said first and said second inflatable balloons.
Claim 10
Dependent Claim
24 words
The ablation catheter of claim 8 wherein said supply means further includes means for circulating a coolant in said first and second inflatable balloons.
Claim 11
Dependent Claim
27 words
The ablation catheter of claim 9 wherein said supply means includes first and second passageways in said elongated member communicating with said first and second inflatable balloons.
Claim 12
Dependent Claim
30 words
The ablation catheter of claim 9 wherein each of said first and second passageways includes a plurality of ports communicating with an interior of said first and second inflatable balloons.
Claim 13
Dependent Claim
20 words
The ablation catheter of claim 11 wherein the ports of each of said plurality of ports include different cross-sectional areas.
Claim 14
Dependent Claim
26 words
The ablation catheter of claim 7 wherein said second inflatable balloon includes an annular recess for positioning the other of said internal and external sphincters therein.
Claim 15
Dependent Claim
34 words
The ablation catheter of claim 7 further comprising first annular means for forming a first annular recess about said first inflatable balloon to position at least one of said internal and external sphincters therein.
Claim 16
Dependent Claim
33 words
The ablation catheter of claim 14 further comprising second annular means for forming a second annular recess about said second inflatable balloon to position the other of said internal and external sphincters therein.
Claim 17
Dependent Claim
20 words
The ablation catheter of claim 7 further comprising means for adjusting a spacing between said first and second inflatable balloons.
Claim 18
Dependent Claim
23 words
The ablation catheter of claim 1 wherein said fixation means includes recess means for positioning said at least one of said sphincters therein.
Claim 19
Dependent Claim
22 words
The ablation catheter of claim 17 wherein said fixation means includes second recess means for positioning the other of said sphincters therein.
Claim 20
Dependent Claim
19 words
The ablation catheter of claim 1 wherein said heat-emitting element comprises a helically wound coil of electrically semiconductive material.
Claim 21
Dependent Claim
25 words
The ablation catheter of claim 1 wherein said heat-emitting element is serpentine shaped and is positioned longitudinally along and partially circumferentially about said intermediate portion.
Claim 22
Dependent Claim
15 words
The ablation catheter of claim 1 further comprising a temperature sensor in said intermediate portion.
Claim 23
Dependent Claim
13 words
The ablation catheter of claim 21 wherein said temperature sensor comprises a thermistor.
Claim 24
Dependent Claim
16 words
The ablation catheter of claim 1 wherein said elongated member includes a passageway extending longitudinally therein.
Claim 25
Dependent Claim
93 words
A transurethral ablation catheter for ablating prostatic tissue positioned between internal and external sphincters, comprising: an elongated member having a distal portion, a proximal portion, and an intermediate portion positioned between said distal and proximal portions, said distal and proximal portions including cooling means positionable about at least one of said internal and external sphincters for cooling said at least one of said internal and external sphincters; and a heating element positioned about said intermediate portion and responsive to energy supplied thereto for producing a temperature in said tissue to ablate said tissue.
Claim 26
Dependent Claim
93 words
A transurethral ablation catheter for ablating prostatic tissue positioned between internal and external sphincters, comprising: an elongated member having a distal portion, a proximal portion, and an intermediate portion positioned between said distal and proximal portions, said distal and proximal portions including cooling means positionable about at least one of said internal and external sphincters for cooling said at least one of said internal and external sphincters; and a heating element positioned about said intermediate portion and responsive to energy supplied thereto for producing a temperature in said tissue to ablate said tissue.
Claim 27
Dependent Claim
88 words
A transurethral catheter for ablating prostatic tissue between internal and external sphincters, comprising: first and second elongated coaxial members longitudinally movable relative to each other, said first member having first fixation means for positioning said internal sphincter thereabout, said second member having second fixation means for positioning said external sphincter thereabout; and one of said members including a thermally conductive heat-emitting element positioned between said first and second fixation means and responsive to energy supplied thereto for producing a predetermined, thermally conductive heat distribution in said prostatic tissue.
Claim 28
Dependent Claim
88 words
A transurethral catheter for ablating prostatic tissue between internal and external sphincters, comprising: first and second elongated coaxial members longitudinally movable relative to each other, said first member having first fixation means for positioning said internal sphincter thereabout, said second member having second fixation means for positioning said external sphincter thereabout; and one of said members including a thermally conductive heat-emitting element positioned between said first and second fixation means and responsive to energy supplied thereto for producing a predetermined, thermally conductive heat distribution in said prostatic tissue.
Claim 29
Dependent Claim
28 words
The catheter of claim 25 wherein said first and second fixation means includes respective first and second annular recesses for positioning said internal and external sphincters therein, respectively.
Claim 30
Dependent Claim
39 words
The catheter of claim 26 wherein said first and second fixation means includes respective first and second inflatable balloons responsive to coolant supplied thereto for maintaining a temperature of said internal and external sphincters below a predetermined maximum temperature.
Claim 31
Independent Claim
147 words
A system for ablating prostatic tissue between internal and external sphincters, comprising: heat-emitting catheter means transurethrally positionable in said prostatic tissue through at least one of said internal and external sphincters and responsive to energy supplied thereto for producing a predetermined, thermally conductive heat distribution in said prostatic tissue to ablate said prostatic tissue, said heat-emitting catheter means including sphincter cooling means positionable about at least one of said internal and external sphincters and responsive to a coolant supplied thereto for maintaining said at least one of said sphincters below a predetermined maximum temperature; said heat-emitting catheter means including temperature sensor means for measuring temperature thereabout; and control means responsive to said temperature measured about said sensor means and said energy supplied to said heat-emitting catheter means for controlling the energy supplied to said heat-emitting catheter means to produce said predetermined, heat distribution in said prostatic tissue.
Claim 32
Independent Claim
147 words
A system for ablating prostatic tissue between internal and external sphincters, comprising: heat-emitting catheter means transurethrally positionable in said prostatic tissue through at least one of said internal and external sphincters and responsive to energy supplied thereto for producing a predetermined, thermally conductive heat distribution in said prostatic tissue to ablate said prostatic tissue, said heat-emitting catheter means including sphincter cooling means positionable about at least one of said internal and external sphincters and responsive to a coolant supplied thereto for maintaining said at least one of said sphincters below a predetermined maximum temperature; said heat-emitting catheter means including temperature sensor means for measuring temperature thereabout; and control means responsive to said temperature measured about said sensor means and said energy supplied to said heat-emitting catheter means for controlling the energy supplied to said heat-emitting catheter means to produce said predetermined, heat distribution in said prostatic tissue.
Claim 33
Dependent Claim
61 words
The system of claim 28 wherein said heat-emitting catheter means further includes second temperature sensor means positioned about said sphincter cooling means for determining a temperature of said at least one of said sphincters and wherein said control means is responsive to the temperature of said at least one of said sphincters for controlling the coolant supplied to said cooling means.
Claim 34
Dependent Claim
63 words
The system of claim 28 wherein said sphincter cooling means includes first cooling means positionable about said internal sphincter and responsive to a coolant supplied thereto for maintaining said internal sphincter below a predetermined maximum temperature and a second cooling means positionable about said external sphincter and responsive to a coolant supplied thereto for maintaining said external sphincter below a predetermined maximum temperature.
Claim 35
Dependent Claim
89 words
The system of claim 30 wherein said heat-emitting catheter means further includes second temperature sensor means positioned about said first cooling means for determining a temperature of said internal sphincter and third temperature sensor means positioned about said second cooling means for determining a temperature of said external sphincter and wherein said control means is responsive to the temperatures of said internal and external sphincters and to the coolant supplied to said first and second cooling means for controlling the coolant supplied to said first and second cooling means.
Claim 36
Dependent Claim
24 words
The system of claim 31 further comprising means responsive to said control means for supplying the coolant to said first and second cooling means.
Claim 37
Dependent Claim
22 words
The system of claim 32 further comprising means responsive to said control means for supplying the energy to said heat-emitting catheter means.
Claim 38
Independent Claim
134 words
A system for ablating prostatic tissue between internal and external sphincters comprising: catheter means transurethrally positionable in said prostatic tissue through at least one of said internal and external sphincters and responsive to energy supplied thereto for producing a temperature in said tissue to ablate said tissue between said internal and external sphincters, said catheter means including cooling means positionable about at least one of said internal and external sphincters and responsive to a coolant supplied thereto for maintaining said at least one of said sphincters below a predetermined maximum temperature; said catheter means including sensor mean for sensing temperature thereabout; and control means responsive to said temperature sensed about said sensor means and said energy supplied to said catheter means for controlling the energy supplied to said catheter means to ablate said tissue.
Claim 39
Independent Claim
134 words
A system for ablating prostatic tissue between internal and external sphincters comprising: catheter means transurethrally positionable in said prostatic tissue through at least one of said internal and external sphincters and responsive to energy supplied thereto for producing a temperature in said tissue to ablate said tissue between said internal and external sphincters, said catheter means including cooling means positionable about at least one of said internal and external sphincters and responsive to a coolant supplied thereto for maintaining said at least one of said sphincters below a predetermined maximum temperature; said catheter means including sensor mean for sensing temperature thereabout; and control means responsive to said temperature sensed about said sensor means and said energy supplied to said catheter means for controlling the energy supplied to said catheter means to ablate said tissue.
Claim 40
Dependent Claim
21 words
The system of claim 34 further comprising means responsive to said control means for supplying the coolant to said cooling means.
Claim 41
Independent Claim
54 words
A method for treating prostatic hyperplasia comprising: positioning a heat-emitting catheter transurethrally into a prostatic urethra; selectively applying heat to said prostatic urethra between internal and external sphincters for producing an ablative temperature in said prostatic urethra; and cooling at least one of said internal and external sphincters to below a predetermined maximum temperature.
Claim 42
Independent Claim
54 words
A method for treating prostatic hyperplasia comprising: positioning a heat-emitting catheter transurethrally into a prostatic urethra; selectively applying heat to said prostatic urethra between internal and external sphincters for producing an ablative temperature in said prostatic urethra; and cooling at least one of said internal and external sphincters to below a predetermined maximum temperature.
Claim 43
Dependent Claim
27 words
The method of claim 36 wherein the step of positioning said catheter includes positioning said catheter relative to at least one of said internal and external sphincters.
Claim 44
Dependent Claim
20 words
The method of claim 36 further comprising coagulating blood perfusing about said prostatic urethra in response to said ablative temperature.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-04-18 | 1997-10-18 | 1998-04-19 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-04-18 | 2001-10-18 | 2002-04-19 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-04-18 | 2005-10-18 | 2006-04-19 | $7700.00 | Window Closed / Lapsed |