US5298222A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Process for disinfecting musculoskeletal tissue and tissues prepared thereby
Assignee: Warsaw Orthopedic Inc
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Filing: 1989-08-09
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Granted: 1994-03-29
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Expires: 2009-08-09
Abstract
Abstract A process for treating musculoskeletal tissue which comprises contacting musculoskeletal tissue with both an effective amount of at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the tissue, such as a surfactant or a permeation enhancer. The disinfectant and/or antibiotic function in killing bacteria, vegetative organisms, and viruses (including HIV virus) which may be remaining in the musculoskeletal tissue. A preferred disinfectant is ethanol.
Inventors
- 👤 Robert K. O'Leary
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-22 23:02
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/36; A61K; A61K31/00; A61K31/045; A61L2/00; A61L2/16; A61L2/18; A61L2103/00; A61L2103/05; A61L2430/00; A61L2430/02
Claims Analysis
Total Claims: 14
Claim 1
Independent Claim
51 words
A process for treating bone with both an effective amount of at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the bone, said agent being selected from the group consisting of surfactants and permeation enhancers.
Claim 2
Dependent Claim
51 words
A process for treating bone with both an effective amount of at least one treating agent selected from the class consisting of antibiotics and disinfectants, and an agent to increase diffusion of the treating agent into the bone, said agent being selected from the group consisting of surfactants and permeation enhancers.
Claim 3
Dependent Claim
14 words
The process of claim 1 wherein the treating agent is at lest one antibiotic.
Claim 4
Dependent Claim
25 words
The process of claim 2 wherein said at least one antibiotic is added in an amount of from about 30,000 units to about 50,000 units.
Claim 5
Dependent Claim
14 words
The process of claim 1 wherein the treating agent is at least one disinfectant.
Claim 6
Dependent Claim
16 words
The process of claim 4 wherein said at least one disinfectant is an aqueous ethanol solution.
Claim 7
Dependent Claim
29 words
The process of claim 4 wherein said at least one disinfectant is added in an aqueous solution in an amount of from about 1% to about 100% by volume.
Claim 8
Dependent Claim
21 words
The process of claim 1 wherein said agent to increase diffusion of the treating agent into the bone is a surfactant.
Claim 9
Dependent Claim
12 words
The process of claim 7 wherein the surfactant is a non-ionic surfactant.
Claim 10
Dependent Claim
17 words
The process of claim 7 wherein the surfactant is miscible with said at least one treating agent.
Claim 11
Dependent Claim
22 words
The process of claim 1 wherein said agent to increase diffusion of the treating agent into the bone is a permeation enhancer.
Claim 12
Dependent Claim
31 words
The process of claim 1 wherein said at least one treating agent and said agent to increase diffusion of the treating agent into the bone are applied as an aqueous mixture.
Claim 13
Dependent Claim
36 words
The process of claim 1 wherein the agent to increase diffusion of the treating agent into the bone is added in an aqueous solution in an amount of from about 0.0001% to about 10% by volume.
Claim 14
Dependent Claim
32 words
The process of claim 12 wherein the agent to increase diffusion of the treating agent into the bone is added in an amount of from about 0.01% to about 10% by volume.
References Cited (Backward Citations)
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Cited
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Cited
US4277238A
Cited
US4379143A
Cited
WO1984001894A1
Cited
WO1988003411A1
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-03-28 | 1997-09-27 | 1998-03-29 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-03-28 | 2001-09-27 | 2002-03-29 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-03-28 | 2005-09-27 | 2006-03-29 | $7700.00 | Window Closed / Lapsed |