Process of producing bioabsorbable filaments

Claim 2

In the process of preparing a stretch-oriented, bioabsorbable poly(hydroxycarboxylic acid) filament, the process comprising the steps of: spinning a bioabsorbable poly(hydroxycarboxylic acid) into a filament to produce an as-spun filament, and drawing the as-spun filament to produce the stretch-oriented filament; the improvement wherein: the step of applying to the as-spun filament, prior to the drawing step, a lubricant that is biocompatible with mammals, has sufficient lubricity to minimize filament-to-filament friction and filament breakage, is liquid at the temperature of application, is hydrophobic, and has a viscosity at the temperature of application of about 1 to about 100 cp.

Claim 3

The process of claim 1 wherein the lubricant comprises a silicone oil having a molecular weight less than about 4000 and a viscosity at room temperature in the range of 1 to 100 cp.

Claim 4

The process of claim 1 wherein the poly(hydroxycarboxylic acid) comprises a polymer containing repeating units of the formula --C(R'R")--CO--O-- where R' and R" are the same or different and are H or lower alkyl, at least one of R' and R" being H.

Claim 5

The process of claim 3 wherein R' and R" are each H in a major amount of the repeating units of the polymer.

Claim 6

The process of claim 3 wherein R' is H and R" is methyl in a major amount of the repeating units of the polymer.

Claim 7

The process of claim 1 wherein said as-spun filament is stretch oriented at a draw ratio ranging from about 2X to abut 20X.

Claim 8

The process of claim 1 wherein the stretch-oriented filament exits from the drawing step at a speed of at least 1000 meters per minute.

Claim 9

The process of claim 1 wherein the drawing step is carried out substantially immediately after the application of the lubricant to the as-spun filament.

Claim 10

The process of claim 8 wherein the lubricant has a viscosity at room temperature in the range 1-10 cp.

Claim 11

A process for the production of bioabsorbable poly(hydroxycarboxylic acid) filaments, comprising the steps of: spinning bioabsorbable poly(hydroxycarboxylic acid) into a filament, without intermediate collection of the spun filament, applying a lubricant to the spun filament and stretch-orienting said filament at a draw ratio of at least 2X, said lubricant being a silicone oil; a liquid, lower aliphatic stearate ester; a liquid, lower aliphatic polyol ester of a C 8 to C 10 aliphatic carboxylic acid; or a mixture thereof, said lubricant having a room temperature viscosity in the range of about 1 to about 100 cp, and collecting the resulting stretch-oriented filament at a windup speed greater than 100 m/min.

Claim 12

A process for the production of bioabsorbable poly(hydroxycarboxylic acid) filaments, comprising the steps of: spinning bioabsorbable poly(hydroxycarboxylic acid) into a filament, without intermediate collection of the spun filament, applying a lubricant to the spun filament and stretch-orienting said filament at a draw ratio of at least 2X, said lubricant being a silicone oil; a liquid, lower aliphatic stearate ester; a liquid, lower aliphatic polyol ester of a C 8 to C 10 aliphatic carboxylic acid; or a mixture thereof, said lubricant having a room temperature viscosity in the range of about 1 to about 100 cp, and collecting the resulting stretch-oriented filament at a windup speed greater than 100 m/min.

Claim 13

The process of claim 10, wherein a said lubricant is a silicone oil or a silicone oil in admixture with a said stearate ester or a said polyol ester, and wherein the resulting stretch-oriented filament is collected at a windup speed greater than 1000 m/min.

Claim 14

The process of claim 10, wherein said draw ratio is at least about 5X.

Claim 15

The process of claim 10, wherein a said lubricant is a silicone oil having a room temperature viscosity of about 1 to about 10 cp.

Claim 16

The process of claim 10, wherein the denier of the spun and stretch-oriented filament does not exceed 30.

Claim 17

The process of claim 10, wherein a plurality of said filaments are spun and combined into a multifilament structure, and said multifilament structure is lubricated and stretch-oriented.

Claim 18

The process of claim 15, wherein the denier per filament of said multifilament structure does not exceed 30.

Claim 19

The process of claim 10 wherein said poly(hydroxycarboxylic acid) comprises a polymer containing repeating units of the formula --C(R'R")--CO--O-- where R' and R" are the same or different and are H or lower alkyl and, at least one of R' and R" being H.

Claim 20

The process of claim 17 wherein (1) one of R' and R" is hydrogen and (2) the other is hydrogen or methyl.

Claim 21

The process of claim 10 wherein the poly(hydroxycarboxylic acid) is selected from the group consisting of (1) polyglycolic acid, (2) polylactic acid, (3) copolymers containing major amounts of one or both of glycolic acid and lactic acid, and (4) polymer blends containing major amounts of one or both of polyglycolic acid and polylactic acid.