US5281215A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Cryogenic catheter
Assignee: Medtronic Cryocath LP
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Filing: 1992-06-15
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Granted: 1994-01-25
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Expires: 2012-06-15
Abstract
Abstract The invention provides a catheter for ice mapping and ablation and a method of ablation using the catheter. The catheter includes at least two lumens for circulating a refrigerating fluid adjacent an ablation device located at the end of a catheter. The refrigerated ablation device is used to chill a localized region of myocardial tissue, thereby permitting the resulting change in electrical activity to be determined. In response to the test results, the ablation device may be used to make a lesion in the myocardial tissue to correct a cardiac arrhythmia. In one embodiment, the ablation device is an electrode which uses radio frequency energy to ablate the myocardial tissue. Alternatively, the ablation device is an electrode adapted for direct current ablation. In another embodiment, the electrode is replaced with an optical fiber in communication with a laser which uses the laser's light energy to ablate tissue. Yet another embodiment is a cryogenic catheter, useful for cooling tissue for other applications, for use as combined or separate mapping and ablation devices, or for use with the ice mapping and ablation means of the present invention. The embodiments may include provisions for steering the catheter and for stabilizing the ablation device at the proposed lesion site.
Inventors
- 👤 Fredric L. Milder
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 09:32
CPC Classifications
A; A61; A61M; A61M25/00; A61M25/01; A61M25/0105; A61M25/0133; A61M25/0158; A61B; A61B18/00; A61B18/02; A61B18/04; A61B18/12; A61B18/14; A61B18/1492; A61B18/18; A61B18/20; A61B18/22; A61B18/24; A61B18/28; A61B17/00; A61B2017/00017; A61B2017/00022; A61B17/00234; A61B2017/00238; A61B2017/00243; A61B2017/00292; A61B2017/003; A61B2018/00005; A61B2018/00011; A61B2018/00023; A61B2018/00053; A61B2018/00059; A61B2018/00071; A61B2018/00077; A61B2018/00089; A61B2018/00095; A61B2018/00315; A61B2018/00345; A61B2018/00351; A61B2018/00357; A61B2018/00571; A61B2018/00577; A61B2018/00636; A61B2018/00773; A61B2018/00791; A61B2018/00815; A61B2018/00821; A61B2018/00839; A61B2018/0212; A61B2018/0231; A61B2018/0262; A61B2018/0268; A61B2018/0275; A61B2018/0281; A61B18/1206; A61B2018/1246; A61B2018/1253; A61B2218/00; A61B2218/001; A61B2218/002; A61B2218/003; A61F; A61F7/00; A61F2007/0054; A61F2007/0056
Claims Analysis
Total Claims: 23
Claim 1
Independent Claim
135 words
A cryogenic catheter comprising: a first lumen; a second lumen; a valve associated with one of said lumens, said valve regulating flow of a cooling fluid between said first lumen and said second lumen, wherein said valve comprises a ball biased against a ball seat with a biasing means, said ball preventing flow of said cooling fluid through a passage within said ball seat until said cooling fluid exerts sufficient pressure against said ball to overcome bias forces imparted thereon, thereby displacing said ball from said ball seat; and a chamber for permitting said cooling fluid to boil, cool, and thereby chill a tissue cooling surface located proximate said chamber, said cooling fluid introduced into said chamber through said valve by way of said first lumen and exhausted from said chamber via said second lumen.
Claim 2
Dependent Claim
135 words
A cryogenic catheter comprising: a first lumen; a second lumen; a valve associated with one of said lumens, said valve regulating flow of a cooling fluid between said first lumen and said second lumen, wherein said valve comprises a ball biased against a ball seat with a biasing means, said ball preventing flow of said cooling fluid through a passage within said ball seat until said cooling fluid exerts sufficient pressure against said ball to overcome bias forces imparted thereon, thereby displacing said ball from said ball seat; and a chamber for permitting said cooling fluid to boil, cool, and thereby chill a tissue cooling surface located proximate said chamber, said cooling fluid introduced into said chamber through said valve by way of said first lumen and exhausted from said chamber via said second lumen.
Claim 3
Dependent Claim
234 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end, said first lumen concentric with said second lumen being sufficiently flexible and sufficiently narrow to be inserted into and travel through a cardiac blood vessel without injuring said cardiac blood vessel; at least one control valve for regulating flow of said cooling fluid from said distal end of said first lumen into a boiling chamber that connects said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state, wherein said control valve has an open and a closed state, for permitting said cooling fluid to pass from said first lumen into said boiling chamber when said at least one control valve is in said open state, said at least one control valve responsive to an electric control signal; and a plurality of temperature sensors for producing said electric control signal, including a temperature sensor located within said second lumen; and a cooling surface proximate said boiling chamber, wherein said cooling surface is a thermal conductor.
Claim 4
Dependent Claim
234 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end, said first lumen concentric with said second lumen being sufficiently flexible and sufficiently narrow to be inserted into and travel through a cardiac blood vessel without injuring said cardiac blood vessel; at least one control valve for regulating flow of said cooling fluid from said distal end of said first lumen into a boiling chamber that connects said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state, wherein said control valve has an open and a closed state, for permitting said cooling fluid to pass from said first lumen into said boiling chamber when said at least one control valve is in said open state, said at least one control valve responsive to an electric control signal; and a plurality of temperature sensors for producing said electric control signal, including a temperature sensor located within said second lumen; and a cooling surface proximate said boiling chamber, wherein said cooling surface is a thermal conductor.
Claim 5
Dependent Claim
33 words
The catheter of claim 2, further comprising a micropore filter positioned within said second lumen to prevent said cooling fluid in a liquid state from exiting said proximal end of said second lumen.
Claim 6
Dependent Claim
25 words
The catheter of claim 3, wherein said micropore filter is a plug of glass wool that substantially fills said distal end of said second lumen.
Claim 7
Dependent Claim
21 words
The catheter of claim 3, wherein said micropore filter is sponge that substantially fills said distal end of said second lumen.
Claim 8
Dependent Claim
217 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; at least one control valve for regulating flow of said cooling fluid from said distal end of said first lumen into a boiling chamber that connects said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state, said at least one control valve comprising: a ball seat; a ball, matable with said ball seat for forming a fluid tight seal, said ball seat having a passage therein for permitting said cooling fluid to pass from said first lumen into said boiling chamber when said ball is displaced; and a biasing means, for biasing said ball toward said ball seat, said biasing means causing said ball to mate with said ball seat until said cooling fluid is pressurized to a predetermined pressure level; and a cooling surface proximate said boiling chamber, wherein said cooling surface is a thermal conductor.
Claim 9
Dependent Claim
217 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; at least one control valve for regulating flow of said cooling fluid from said distal end of said first lumen into a boiling chamber that connects said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state, said at least one control valve comprising: a ball seat; a ball, matable with said ball seat for forming a fluid tight seal, said ball seat having a passage therein for permitting said cooling fluid to pass from said first lumen into said boiling chamber when said ball is displaced; and a biasing means, for biasing said ball toward said ball seat, said biasing means causing said ball to mate with said ball seat until said cooling fluid is pressurized to a predetermined pressure level; and a cooling surface proximate said boiling chamber, wherein said cooling surface is a thermal conductor.
Claim 10
Dependent Claim
12 words
The catheter of claim 6, wherein said biasing means is a spring.
Claim 11
Dependent Claim
13 words
The catheter of claim 6, wherein said biasing means is a compressible pad.
Claim 12
Dependent Claim
16 words
The catheter of claim 2, wherein said at least one control valve comprises a needle valve.
Claim 13
Dependent Claim
16 words
The catheter of claim 2, wherein said at least one control valve comprises a solenoid valve.
Claim 14
Dependent Claim
16 words
The catheter of claim 2, wherein said plurality of temperature sensors comprises at least one thermocouple.
Claim 15
Dependent Claim
16 words
The catheter of claim 2, wherein said plurality of temperature sensors comprises at least one thermistor.
Claim 16
Dependent Claim
204 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; a fluid control valve comprising an electrically controlled valve, said fluid control valve having an open and a closed state for permitting said cooling fluid to pass from said first lumen into a boiling chamber when said fluid control valve is in said open state, said boiling chamber connecting said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state; a cooling surface proximate said expansion chamber, wherein said cooling surface is thermal conductor; a micropore filter positioned within said second lumen to prevent said cooling fluid in a liquid state from exiting said proximal end of said second lumen; and at least one temperature sensor for producing an electric control signal to command said fluid control valve into said open and said closed states.
Claim 17
Dependent Claim
204 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; a fluid control valve comprising an electrically controlled valve, said fluid control valve having an open and a closed state for permitting said cooling fluid to pass from said first lumen into a boiling chamber when said fluid control valve is in said open state, said boiling chamber connecting said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state; a cooling surface proximate said expansion chamber, wherein said cooling surface is thermal conductor; a micropore filter positioned within said second lumen to prevent said cooling fluid in a liquid state from exiting said proximal end of said second lumen; and at least one temperature sensor for producing an electric control signal to command said fluid control valve into said open and said closed states.
Claim 18
Dependent Claim
239 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; a fluid control valve comprising: a ball seat; a ball matable with said ball seat for forming a fluid tight seal, said ball seat having a passage therein for permitting said cooling fluid to pass from said first lumen into a boiling chamber when said ball is displaced, said boiling chamber connecting said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state; and a biasing means, for biasing said ball toward said ball seat, said biasing means causing said ball to mate with said ball seat until said cooling fluid is pressurized to a predetermined pressure level; a cooling surface proximate said boiling chamber and responsive to thermal activity therein; a micropore filter positioned within said second lumen to prevent said cooling fluid in a liquid state from exiting said proximal end of said second lumen; and at least one temperature sensor for producing an electric control signal to command said fluid control valve into open and closed states.
Claim 19
Dependent Claim
239 words
A cryogenic catheter comprising: a first lumen, having a proximal end and a distal end, concentric with a second lumen, said first lumen permitting a cooling fluid to flow from said proximal end to said distal end, said second lumen, having a proximal end and a distal end, permitting said cooling fluid to flow from said distal end to said proximal end; a fluid control valve comprising: a ball seat; a ball matable with said ball seat for forming a fluid tight seal, said ball seat having a passage therein for permitting said cooling fluid to pass from said first lumen into a boiling chamber when said ball is displaced, said boiling chamber connecting said distal end of said first lumen and said distal end of said second lumen, said boiling chamber permitting boiling of said cooling fluid into a gaseous state; and a biasing means, for biasing said ball toward said ball seat, said biasing means causing said ball to mate with said ball seat until said cooling fluid is pressurized to a predetermined pressure level; a cooling surface proximate said boiling chamber and responsive to thermal activity therein; a micropore filter positioned within said second lumen to prevent said cooling fluid in a liquid state from exiting said proximal end of said second lumen; and at least one temperature sensor for producing an electric control signal to command said fluid control valve into open and closed states.
Claim 20
Independent Claim
201 words
A method of cryoablation comprising the steps of: introducing a cryogenic catheter into a cardiac blood vessel, said cryogenic catheter having a proximal end and a distal end, said cryogenic catheter comprising: a first lumen for permitting a cooling fluid to flow from said proximal end to said distal end; a second lumen permitting return of said cooling fluid from said distal end to said proximal end; a valve associated with one of said lumens, said valve regulating flow of said cooling fluid between said first lumen and said second lumen, said valve responsive to at least one electric control signal; a temperature sensor located within said second lumen for providing one of said at least one electric control signal; positioning said distal end of said cryogenic catheter at a proposed lesion site; introducing a cooling fluid into said first lumen to cool said distal end and thereby cool said proposed lesion site to suppress localized cardiac electrical activity; monitoring the temperature within said second lumen with said temperature sensor; testing said proposed lesion site for cardiac activity using electrocardiographic mapping means; evaluating results of said test to confirm effectiveness of said proposed lesion site; and generating a lesion by cryoablation.
Claim 21
Independent Claim
201 words
A method of cryoablation comprising the steps of: introducing a cryogenic catheter into a cardiac blood vessel, said cryogenic catheter having a proximal end and a distal end, said cryogenic catheter comprising: a first lumen for permitting a cooling fluid to flow from said proximal end to said distal end; a second lumen permitting return of said cooling fluid from said distal end to said proximal end; a valve associated with one of said lumens, said valve regulating flow of said cooling fluid between said first lumen and said second lumen, said valve responsive to at least one electric control signal; a temperature sensor located within said second lumen for providing one of said at least one electric control signal; positioning said distal end of said cryogenic catheter at a proposed lesion site; introducing a cooling fluid into said first lumen to cool said distal end and thereby cool said proposed lesion site to suppress localized cardiac electrical activity; monitoring the temperature within said second lumen with said temperature sensor; testing said proposed lesion site for cardiac activity using electrocardiographic mapping means; evaluating results of said test to confirm effectiveness of said proposed lesion site; and generating a lesion by cryoablation.
Claim 22
Independent Claim
240 words
A method of cryoablation comprising the steps of: introducing a cryogenic catheter into a cardiac blood vessel, said cryogenic catheter having a proximal end and a distal end, said cryogenic catheter comprising: a first lumen for permitting a cooling fluid to flow from said proximal end to said distal end; a second lumen permitting return of said cooling fluid from said distal end to said proximal end; a valve associated with one of said lumens, said valve regulating flow of said cooling fluid between said first lumen and said second lumen, said valve responsive to at least one electric control signal; a first temperature sensor located within said second lumen for monitoring the temperature within said second lumen, said first temperature sensor providing one of said at least one electric control signal; a second temperature sensor positioned to monitor thermal activity proximate said distal end, said second temperature sensor providing one of said at least one electric control signal; positioning said distal end of said cryogenic catheter at a proposed lesion site; introducing a cooling fluid into said first lumen to cool said distal end and thereby cool said proposed lesion site to suppress localized cardiac electrical activity; monitoring the temperature within said second lumen with said temperature sensor; testing said proposed lesion site for cardiac activity using electrocardiographic mapping means; evaluating results of said test to confirm effectiveness of said proposed lesion site; and generating a lesion by cryoablation.
Claim 23
Independent Claim
240 words
A method of cryoablation comprising the steps of: introducing a cryogenic catheter into a cardiac blood vessel, said cryogenic catheter having a proximal end and a distal end, said cryogenic catheter comprising: a first lumen for permitting a cooling fluid to flow from said proximal end to said distal end; a second lumen permitting return of said cooling fluid from said distal end to said proximal end; a valve associated with one of said lumens, said valve regulating flow of said cooling fluid between said first lumen and said second lumen, said valve responsive to at least one electric control signal; a first temperature sensor located within said second lumen for monitoring the temperature within said second lumen, said first temperature sensor providing one of said at least one electric control signal; a second temperature sensor positioned to monitor thermal activity proximate said distal end, said second temperature sensor providing one of said at least one electric control signal; positioning said distal end of said cryogenic catheter at a proposed lesion site; introducing a cooling fluid into said first lumen to cool said distal end and thereby cool said proposed lesion site to suppress localized cardiac electrical activity; monitoring the temperature within said second lumen with said temperature sensor; testing said proposed lesion site for cardiac activity using electrocardiographic mapping means; evaluating results of said test to confirm effectiveness of said proposed lesion site; and generating a lesion by cryoablation.
References Cited (Backward Citations)
US3272203A
Cited
US3425419A
Cited
US3393679A
Cited
US3512531A
Cited
US3524446A
Cited
US3548829A
Cited
US3664344A
Cited
US3823718A
Cited
US3910277A
Cited
US3859986A
Cited
US3948269A
Cited
US4022215A
Cited
SU532976A1
Cited
US3971383A
Cited
US4029102A
Cited
DE2613778A1
Cited
DE2731651A1
Cited
US4275734A
Cited
US4278090A
Cited
FR2477406A1
Cited
US4519389A
Cited
US4377168A
Cited
US4406656A
Cited
US4601705A
Cited
WO1986000232A1
Cited
US4641649A
Cited
US4832024A
Cited
US4899741A
Cited
US4770171A
Cited
US4819630A
Cited
US4860744A
Cited
US5147355A
Cited
US5041973A
Cited
US5108390A
Cited
US4934340A
Cited
US5056517A
Cited
US5151096A
Cited
US5161539A
Cited
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1997-01-24 | 1997-07-26 | 1998-01-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2001-01-24 | 2001-07-26 | 2002-01-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2005-01-24 | 2005-07-26 | 2006-01-25 | $7700.00 | Window Closed / Lapsed |