US5263985A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Bone growth stimulator
Assignee: Howmedica Osteonics Corp
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Filing: 1992-11-20
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Granted: 1993-11-23
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Expires: 2012-11-20
Abstract
Abstract An implantable material for promoting bone growth has a microporous structure exhibiting an average pore size of at least 30 Å. The porous biomaterial is capable of retaining macromolecules having a molecular weight of at least 15,000 and up to 500,000.
Inventors
- 👤 Qi-Bin Bao
- 👤 John H. Dumbleton
- 👤 Paul A. Higham
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 15:30
CPC Classifications
A; A61; A61L; A61L27/00; A61L27/28; A61L27/34; Y; Y10; Y10S; Y10S623/00; Y10S623/92; Y10S623/923
Claims Analysis
Total Claims: 5
Claim 1
Independent Claim
98 words
A process for promoting tissue growth around a prosthetic implant comprising: coating the prosthetic implant with a biomaterial having a neutral surface charge and having a microporous structure exhibiting interconnected pores with an average pore size of between 3 nm and 50 nm, such that said biomaterial has a binding effect to osteoinductive protein molecules within said pores; and implanting said prosthetic implant in the body adjacent tissue and promoting bonding of osteoinductive molecules having a molecular weight of at least 15,000 and up to 500,000 within said pores, thereby inducing new bone growth at the implant site.
Claim 2
Dependent Claim
98 words
A process for promoting tissue growth around a prosthetic implant comprising: coating the prosthetic implant with a biomaterial having a neutral surface charge and having a microporous structure exhibiting interconnected pores with an average pore size of between 3 nm and 50 nm, such that said biomaterial has a binding effect to osteoinductive protein molecules within said pores; and implanting said prosthetic implant in the body adjacent tissue and promoting bonding of osteoinductive molecules having a molecular weight of at least 15,000 and up to 500,000 within said pores, thereby inducing new bone growth at the implant site.
Claim 3
Dependent Claim
16 words
The process as set forth in claim 1 wherein the biomaterial is a wetted dextran bead.
Claim 4
Dependent Claim
100 words
A process for promoting tissue growth comprising: forming a prosthetic implant from a multiplicity of uncharged dextran beads having, in the wet state, a neutral surface charge and a microporous structure exhibiting interconnected pores with an average pore size of between 3 nm and 50 nm, such that said biomaterial has binding effect to osteoinductive protein molecules within said pores; and implanting said prosthetic implant in the body adjacent tissue and promoting bonding of osteoinductive molecules having a molecular weight of at least 15,000 and up to 500,000 within said pores, thereby inducing new bone growth at the implant site.
Claim 5
Dependent Claim
100 words
A process for promoting tissue growth comprising: forming a prosthetic implant from a multiplicity of uncharged dextran beads having, in the wet state, a neutral surface charge and a microporous structure exhibiting interconnected pores with an average pore size of between 3 nm and 50 nm, such that said biomaterial has binding effect to osteoinductive protein molecules within said pores; and implanting said prosthetic implant in the body adjacent tissue and promoting bonding of osteoinductive molecules having a molecular weight of at least 15,000 and up to 500,000 within said pores, thereby inducing new bone growth at the implant site.
References Cited (Backward Citations)
USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-11-22 | 1997-05-24 | 1997-11-23 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-11-22 | 2001-05-24 | 2001-11-23 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-11-22 | 2005-05-24 | 2005-11-23 | $7700.00 | Window Closed / Lapsed |