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US5230341A Expired / Lapsed US ⏱️ 0.0 years remaining

Measuring the change of intravascular blood volume during blood filtration

Assignee: Fresenius SE and Co KGaA
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Filing: 1991-02-25
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Granted: 1993-07-27
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Expires: 2011-02-25
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Abstract

Abstract To determine in simple manner the change of the intravascular blood volume during filtration, in the extracorporeal blood circuit (2) of a blood purification apparatus at least one ultrasonic sensor (15) is arranged which is connected to an evaluating unit (18) which is configured in such a manner that at the start of the filtration a first ultrasonic signal is stored and during the filtration the change of the ultrasonic signals is determined. From the change of the ultrasonic signals the change of the hematocrit is determined and from this the change of the intravascular blood volume is deduced.

Inventors

  • 👤 Hans-Dietrich Polaschegg

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 16:33
CPC Classifications
A; A61; A61M; A61M1/00; A61M1/14; A61M1/16; A61M1/1601; A61M1/1603; A61M1/1605; A61M1/36; A61M1/3607; A61M1/3609; A61M1/361; A61M1/3612; A61M2205/00; A61M2205/33; A61M2205/3317; A61M2205/3324; A61M2205/3368; A61M2205/3375; A61M2230/00; A61M2230/20; A61M2230/207

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 186 words
Apparatus for measuring the change in intravascular blood volume occurring during a blood filtration procedure by measuring the change of the hematocrit of the blood, said apparatus being adapted for use with a blood purification device in which the filtration procedure is carried out and which has an extracorporeal blood circuit connected to a patient, said apparatus comprising: a measuring device comprising ultrasonic sensor means adapted to be connected to the extracorporeal blood circuit of the device for ultrasonically examining the blood flowing in the circuit and for providing a signal indicative of the hematocritic properties thereof; and an evaluating unit coupled to said sensor means, said evaluating unit including means for receiving the signal from said ultrasonic sensor means, said evaluating unit including means for storing a signal from said ultrasonic sensor means obtained at the start of the blood filtration procedure, and said evaluating unit including means for determining the change in the signal from said ultrasonic sensor means occurring during the blood filtration procedure for determining the change in the hematocrit of the blood and thus the change in the intravascular blood volume.
Claim 2
Dependent Claim 186 words
Apparatus for measuring the change in intravascular blood volume occurring during a blood filtration procedure by measuring the change of the hematocrit of the blood, said apparatus being adapted for use with a blood purification device in which the filtration procedure is carried out and which has an extracorporeal blood circuit connected to a patient, said apparatus comprising: a measuring device comprising ultrasonic sensor means adapted to be connected to the extracorporeal blood circuit of the device for ultrasonically examining the blood flowing in the circuit and for providing a signal indicative of the hematocritic properties thereof; and an evaluating unit coupled to said sensor means, said evaluating unit including means for receiving the signal from said ultrasonic sensor means, said evaluating unit including means for storing a signal from said ultrasonic sensor means obtained at the start of the blood filtration procedure, and said evaluating unit including means for determining the change in the signal from said ultrasonic sensor means occurring during the blood filtration procedure for determining the change in the hematocrit of the blood and thus the change in the intravascular blood volume.
Claim 3
Dependent Claim 75 words
The apparatus according to claim 1 wherein the extracorporeal blood circuit of the blood purification device has an arterial part for withdrawing blood from the patient and a venous part for returning blood to the patient and wherein said ultrasonic sensor means is further defined as means adapted to be connected to the arterial part of the extracorporeal blood circuit for ultrasonically examining the blood flowing in the arterial part of the extracorporeal blood circuit.
Claim 4
Dependent Claim 209 words
The apparatus according to claim 2 wherein said ultrasonic sensor means comprises first and second ultrasonic sensors, wherein said first ultrasonic sensor is adapted to be connected in the arterial part of the extracorporeal blood circuit for ultrasonically examining the blood flowing in the arterial part of the extracorporeal blood circuit, said first ultrasonic sensor being coupled to said evaluating unit for providing a signal indicative of the hematocritic properties of the blood flowing in the arterial part of the circuit to the evaluating unit, wherein said second ultrasonic sensor is adapted to be connected in the venous part of the extracorporeal blood circuit for ultrasonically examining the blood flowing in the venous part of the extracorporeal blood circuit, said second ultrasonic sensor being coupled to said evaluating unit for providing a signal indicative of the hematocritic properties of the blood flowing in the venous part of the circuit to the evaluating unit, and wherein said evaluating unit is further defined as including means for determining the relative change in the signals received from said first ultrasonic sensor and said second ultrasonic sensor occurring during a blood filtration procedure for determining the relative change of the hematocrit of the blood and thus the relative change in intravascular blood volume.
Claim 5
Dependent Claim 45 words
The apparatus according to claim 1 further including a temperature measuring device adapted to be connected to the extracorporeal blood circuit and coupled to said evaluating unit, said evaluating unit including means for correcting the determination of the hematocrit of the blood for temperature changes.
Claim 6
Dependent Claim 28 words
The apparatus according to claim 4 including a plurality of temperature measuring devices adapted to be connected to the extracorporeal blood circuit and coupled to said evaluating unit.
Claim 7
Dependent Claim 43 words
The apparatus according to claim 1 wherein the blood purification apparatus has a control unit for controlling the filtration procedure and wherein said evaluating unit is further defined as adapted to be connected to said control unit for providing an input signal thereto.
Claim 8
Dependent Claim 27 words
The apparatus according to claim 1 further including means for detecting air in the extracorporeal blood circuit, said air detecting means being connected to said evaluating unit.
Claim 9
Dependent Claim 66 words
The apparatus according to claim 1 wherein the extracorporeal blood circuit of the blood purification device has a drip chamber and wherein said ultrasonic sensor means is adapted to be connected to the drip chamber for providing a signal indicative of liquid levels in the drip chamber, said evaluating unit including means responsive to the liquid levels signal for determining liquid levels in the drip chamber.
Claim 10
Dependent Claim 56 words
The apparatus according to claim 1 wherein said apparatus further including a Doppler blood flow measuring device adapted to be connected to the extracorporeal blood circuit for measuring the flow properties of the blood in the extracorporeal blood circuit and for providing a signal in accordance therewith, said measuring device being coupled to said evaluating unit.

References Cited (Backward Citations)

US3964479A Cited
US4353368A Cited
EP0018817A1 Cited
EP0089003A2 Cited
US4432231A Cited
US4797655A Cited
DE3640089A1 Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-07-26 1997-01-25 1997-07-27 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-07-26 2001-01-25 2001-07-27 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-07-26 2005-01-25 2005-07-27 $7700.00 Window Closed / Lapsed

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