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US5215520A Expired / Lapsed US ⏱️ 0.0 years remaining

Method for delivering an active substance topically or percutaneously

Assignee: Galderma Research and Development SNC
•
Filing: 1991-09-17
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Granted: 1993-06-01
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Expires: 2011-09-17
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Abstract

Abstract A method for the topical or percutaneous administration of a cosmetic or pharmaceutically active substance involves applying an electric current to an area of the skin, ceasing to apply the electric current to this area of the skin and then applying an active substance to at least a part of this area of the skin in the absence of an electric current being applied thereto.

Inventors

  • 👤 Braham Shroot
  • 👤 Philip Green

Bibliographic Details

Application Number —
Jurisdiction US
Data Source google_patents
Last Synchronized 2026-10-23 17:59
CPC Classifications
A; A61; A61N; A61N1/00; A61N1/18; A61N1/20; A61N1/30; A61M; A61M35/00; A61M37/00

Claims Analysis

Total Claims: 10
Claim 1
Independent Claim 71 words
A method for the topical or percutaneous administration of at least one cosmetic or pharmaceutically active substance comprising, in a first stage, applying to an area of the skin an electric current, ceasing to apply said electric current and, in a second stage, applying an active substance to be administered to at least a part of said area of the skin in the absence of an electric current being applied thereto.
Claim 2
Independent Claim 71 words
A method for the topical or percutaneous administration of at least one cosmetic or pharmaceutically active substance comprising, in a first stage, applying to an area of the skin an electric current, ceasing to apply said electric current and, in a second stage, applying an active substance to be administered to at least a part of said area of the skin in the absence of an electric current being applied thereto.
Claim 3
Dependent Claim 31 words
The method of claim 1 wherein the step of applying an electric current includes the step of applying a current having a density of from 0.01 to 0.5 mA/cm 2 .
Claim 4
Dependent Claim 34 words
The method of claim 1 wherein the step of applying an electric current includes the step of applying a pulsed current of 0.05 to 40 KHz with an off/on ratio of 1:1 to 8:1.
Claim 5
Dependent Claim 33 words
The method of claim 1 wherein the step of applying an electric current in said first stage includes applying said current for a period of time ranging from 2 minutes to 6 hours.
Claim 6
Dependent Claim 42 words
The method of claim 1 wherein the step of applying an active substance to said area of the skin in said second stage includes applying said active substance thereto within 30 minutes after ceasing to apply electric current in said first stage.
Claim 7
Dependent Claim 23 words
The method of claim 1 wherein said second stage is carried out immediately after ceasing to apply electric current in said first stage.
Claim 8
Dependent Claim 18 words
The method of claim 1 which includes cleaning the skin between said first stage and said second stage.
Claim 9
Independent Claim 89 words
A method for the topical or percutaneous administration of at least one cosmetic or pharmaceutically active substance comprising, in a first stage, applying to an area of the skin an electric current, ceasing to apply said electric current and cleaning said area of the skin to which the electric current in said first stage was applied, and in a second stage applying an active substance to be administered to at least a part of said area of the skin in the absence of an electric current being applied thereto.
Claim 10
Independent Claim 89 words
A method for the topical or percutaneous administration of at least one cosmetic or pharmaceutically active substance comprising, in a first stage, applying to an area of the skin an electric current, ceasing to apply said electric current and cleaning said area of the skin to which the electric current in said first stage was applied, and in a second stage applying an active substance to be administered to at least a part of said area of the skin in the absence of an electric current being applied thereto.

References Cited (Backward Citations)

US3964477A Cited
US4141359A Cited
US4301794A Cited
US4406658A Cited
US4474570A Cited
US4764164A Cited
US4878892A Cited
GB2206493A Cited

USPTO Annuity & Maintenance Windows

Annuity Stage Window Opens Payment Deadline Surcharge Period Until Estimated Fee Status
3.5 Years (Year 4) 1996-05-31 1996-11-30 1997-06-01 $2000.00 Window Closed / Lapsed
7.5 Years (Year 8) 2000-05-31 2000-11-30 2001-06-01 $3760.00 Window Closed / Lapsed
11.5 Years (Year 12) 2004-05-31 2004-11-30 2005-06-01 $7700.00 Window Closed / Lapsed

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