US5213577A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Device for examining the functions of the endothelium or the intima of blood vessels
Assignee: Siemens Healthcare Diagnostics Inc
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Filing: 1990-12-21
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Granted: 1993-05-25
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Expires: 2010-12-21
Abstract
Abstract The invention relates to a device for examining the functions of the endothelium or the intima of blood vessels. A tube (1) has at least one outlet (6) and at least one inlet (7) spaced along the wall thereof. Outlet (6) communicates with a connector (8), inlet (7) communicates with another connector (9). Connectors (8, 9) are provided in tube (1) at the end thereof projecting from blood vessel (4).
Inventors
- 👤 Michael Kratzer
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 11:05
CPC Classifications
A; A61; A61B; A61B10/00; A61B10/02; A61M; A61M25/00; A61M25/0067; A61M25/0068; A61M25/007; A61B17/00; A61B17/22; A61B2017/22051; A61B2017/22054; A61B2017/22082; A61M25/10; A61M2025/1043; A61M2025/1052
Claims Analysis
Total Claims: 18
Claim 1
Independent Claim
148 words
A device for examining a function of the endothelium or the intima of a blood vessel, comprising: a tube having in its wall at least one outlet and an inlet in spaced relationship to each other; first and second connectors; said outlet and said inlet communicating with said first and second connectors, respectively; said first and second connectors extending from an end of the tube projecting from the blood vessel; a reservoir communicating with the first connector for holding and discharging a solution through the first connector and the outlet into the blood vessel; and analysis means communicating with the second connector for receiving a solution from the blood vessel through the inlet and second connector; said analysis means detecting differences between the solution from the reservoir and the solution from the blood vessel to determine a function of the endothelium or the intima of the blood vessel.
Claim 2
Independent Claim
148 words
A device for examining a function of the endothelium or the intima of a blood vessel, comprising: a tube having in its wall at least one outlet and an inlet in spaced relationship to each other; first and second connectors; said outlet and said inlet communicating with said first and second connectors, respectively; said first and second connectors extending from an end of the tube projecting from the blood vessel; a reservoir communicating with the first connector for holding and discharging a solution through the first connector and the outlet into the blood vessel; and analysis means communicating with the second connector for receiving a solution from the blood vessel through the inlet and second connector; said analysis means detecting differences between the solution from the reservoir and the solution from the blood vessel to determine a function of the endothelium or the intima of the blood vessel.
Claim 3
Dependent Claim
55 words
A device as in claim 1, including seal means provided laterally adjacent said outlet and said inlet, respectively, and on opposite sides of an area defined by the outlet and the inlet; said seal means adapted to selectively provide a seal between the periphery of the tube and an inner wall of the blood vessel.
Claim 4
Dependent Claim
67 words
A device as in claim 2, wherein said seal means includes a plastic inflatable seal member concentrically surrounding the tube and having first and second spaced annular zones in which the material of the seal member is more flexible than the material in other areas of the seal member, so that said zones may flex outwardly in response to a medium inside the seal member being pressurized.
Claim 5
Dependent Claim
50 words
A device as in claim 3, wherein the seal member includes a third zone extending between the first and second zones along only one portion of the circumference of the seal member, said third zone consisting of said comparatively more flexible material than the other areas of the seal member.
Claim 6
Dependent Claim
86 words
A device as in claim 2, wherein said seal means includes an annular inflatable cuff-like plastic member placed over the tube and having a central portion and end portions, said end portions being comparatively more flexible than said central portion, and a conduit sealingly connected with the cuff-like plastic member in such a manner that a medium in the conduit and in the cuff-like plastic member when pressurized causes the end portions to flex outwardly to establish seals with the inner wall of the blood vessel.
Claim 7
Dependent Claim
12 words
A device as in claim 5, wherein said conduit concentrically surrounds tube.
Claim 8
Dependent Claim
48 words
A device as in claim 5, wherein said annular inflatable cuff-like plastic member has an inner diameter which is greater than the outer diameter of the tube when the medium is pressurized so as to form a passage for blood between the tube and the cuff-like plastic member.
Claim 9
Dependent Claim
22 words
A device as in claim 5, wherein said conduit extends inside the tube and sealingly extends through the wall of the tube.
Claim 10
Dependent Claim
120 words
A device as in claim 1, further comprising: a second tube disposed inside the first tube with one end of the second tube being located inside the first tube; a first partition in the first tube spaced from the one end of the second tube and sealing the lumen of the first tube; a second partition disposed--as seen from the first partition in the first tube--behind the one end of the second tube to seal the annular space between the second tube and the first tube said outlet communicating with the space between the first and second partitions; and said inlet being located in the area behind the second partition as seen from the first partition in the first tube.
Claim 11
Dependent Claim
23 words
A device as in claim 1, wherein the tube has an end portion tapered to a tip for introduction in a blood vessel.
Claim 12
Dependent Claim
34 words
A device as in claim 9, wherein the first tube has an end portion for extending into a blood vessel and which has a shape of a head portion rounded at its free end.
Claim 13
Dependent Claim
36 words
A device as in claim 11, wherein the head portion has a passage therein extending from the free end thereof to one side of the head portion, said passage being provided to receive a guide wire.
Claim 14
Dependent Claim
26 words
A device as in claim 1, wherein the tube has a plurality of outlets and a plurality of inlets distributed along circumferential areas of the tube.
Claim 15
Dependent Claim
39 words
A device as in claim 3, wherein said outlet and said inlet have the form of respective openings in the wall of the tube, said seal member having sealed openings in the area of the openings in the tube.
Claim 16
Dependent Claim
42 words
A device as in claim 3, wherein said outlet and said inlet each have the form of a short tubular stub extending through the wall of the tube, with the plastic seal member having sealed openings in the areas of said stubs.
Claim 17
Dependent Claim
11 words
A device as in claim 1, wherein the tube is metal.
Claim 18
Dependent Claim
15 words
A device as in claim 9, wherein said second tube consists of plastic or metal.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-05-24 | 1996-11-23 | 1997-05-25 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-24 | 2000-11-23 | 2001-05-25 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-24 | 2004-11-23 | 2005-05-25 | $7700.00 | Window Closed / Lapsed |