US5207674A
Expired / Lapsed
US
⏱️ 0.0 years remaining
Electronic cryogenic surgical probe apparatus and method
Assignee: Individual
•
Filing: 1991-05-13
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Granted: 1993-05-04
•
Expires: 2011-05-13
Abstract
Abstract A thermoelectric cryoprobe for the topical treatment of neoplasms by freezing. The cryoprobe comprises a plurality of stacked thermoelectric modules coupled to a distal treatment tip through a heat pipe. Heat is dissipated by a heat exchanger system. An external control unit is provided which serves as a source of DC power for the hand-held cryoprobe and contains a control system for controlling the thermoelectric element based upon temperature feedback from treatment site. Temperature feedback from the sensors facilitates freeze-thaw cycling by the cryoprobe to more effectively destroy the tissue at the treatment site.
Inventors
- 👤 Archie C. Hamilton
Bibliographic Details
Application Number
—
Jurisdiction
US
Data Source
google_patents
Last Synchronized
2026-10-23 19:32
CPC Classifications
F; F25; F25B; F25B21/00; F25B21/02; A; A61; A61B; A61B18/00; A61B18/02; A61B46/00; A61B46/10; A61B46/13; A61B46/17; F28; F28D; F28D15/00; F28D15/02; A61B17/00; A61B2017/00017; A61B2017/00022; A61B2017/00084; A61B2018/00005; A61B2018/0231; A61B2018/0237; A61B2018/0243; A61B2018/025
Claims Analysis
Total Claims: 35
Claim 1
Independent Claim
150 words
An electronic cryoprobe for treating tissue comprising: a) a thermoelectric cooling module; b) a heat pipe coupled to said thermoelectric cooling module wherein heat is transferred from said heat pipe to said cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from a tissue treatment site to said heat pipe; d) an electric power means for supplying power to said thermoelectric cooling module; e) a control means connected to said thermoelectric cooling module for regulating the rate of heat transferred by said cooling module; and f) a sensing means connected to said control means for detecting the heat loss transferred from said treatment site to said electronic cryoprobe, wherein said sensing means relays temperature information to said control means, and wherein said control means processes said information to generate a multiple freeze-thaw cycle to be delivered by said electronic cryoprobe to said treatment site.
Claim 2
Dependent Claim
150 words
An electronic cryoprobe for treating tissue comprising: a) a thermoelectric cooling module; b) a heat pipe coupled to said thermoelectric cooling module wherein heat is transferred from said heat pipe to said cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from a tissue treatment site to said heat pipe; d) an electric power means for supplying power to said thermoelectric cooling module; e) a control means connected to said thermoelectric cooling module for regulating the rate of heat transferred by said cooling module; and f) a sensing means connected to said control means for detecting the heat loss transferred from said treatment site to said electronic cryoprobe, wherein said sensing means relays temperature information to said control means, and wherein said control means processes said information to generate a multiple freeze-thaw cycle to be delivered by said electronic cryoprobe to said treatment site.
Claim 3
Dependent Claim
29 words
The electronic cryoprobe of claim 1 further comprising a heat exchanging means coupled to said cooling module for transferring heat from said cooling module to said heat exchanging means.
Claim 4
Dependent Claim
53 words
The electronic cryoprobe of claim 1 wherein said multiple freeze-thaw cycle is generated by the control means selectively increasing, and then selectively decreasing the voltage from said electric power means to said thermoelectric cooling module and wherein said selective increasing and decreasing in voltage is continued until the tissue being treated is destroyed.
Claim 5
Dependent Claim
76 words
The electronic cryoprobe of claim 1 wherein said multiple freeze-thaw cycle is generated by the control means selectively delivering constant voltage from said electric power means to said thermoelectric cooling module, causing the tissue to be cooled, followed by the said control means reversing the polarity of the voltage delivered to said thermoelectric module, causing the tissue to be warmed, and wherein said cycling in voltage polarity is continued until the tissue being treated is destroyed.
Claim 6
Dependent Claim
19 words
The electronic cryoprobe of claim 1 wherein said sensing means is coupled to the application tip of said cryoprobe.
Claim 7
Dependent Claim
18 words
The electronic cryoprobe of claim 1 wherein said sensing means is placed within the tissue subject to treatment.
Claim 8
Dependent Claim
21 words
The electronic cryoprobe of claim 6 wherein said sensing means consists of hypodermic thermocouple capable of being imbedded in said tissue.
Claim 9
Dependent Claim
21 words
The electronic cryoprobe of claim 1 wherein said heat pipe is capable of being detachably coupled to said thermoelectric cooling module.
Claim 10
Dependent Claim
20 words
The electronic cryoprobe of claim 1 wherein said application tip is capable of being detachably fitted to said heat pipe.
Claim 11
Dependent Claim
34 words
The electronic cryoprobe of claim 2 wherein said thermoelectric cooling module is capable of generating sustained temperatures of at least -55° C. by transferring heat from said cooling module to said heat exchanging means.
Claim 12
Dependent Claim
188 words
An electronic cryoprobe for treating tissue comprising: a) a thermoelectric cooling module wherein upon being provided with electric power said cooling module displays opposing hot and cold surfaces; b) a heat pipe coupled to said thermoelectric cooling module wherein heat is transferred from said heat pipe to the cold surface of said cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from a tissue treatment site to said heat pipe; d) a heat exchanging means coupled to the hot surface of said cooling module for transferring heat from said cooling module to said heat exchanging means and into the ambient air; e) a control means connected to said thermoelectric cooling module for regulating the rate of heat transferred by said cooling module; and f) a sensing means connected to said control means for detecting the heat loss transferred from said treatment site to said electronic cryoprobe, wherein said sensing means relays temperature information to said control means, and wherein said control means processes said information to generate a multiple freeze-thaw cycle to be delivered by said electronic cryoprobe to said treatment site.
Claim 13
Dependent Claim
188 words
An electronic cryoprobe for treating tissue comprising: a) a thermoelectric cooling module wherein upon being provided with electric power said cooling module displays opposing hot and cold surfaces; b) a heat pipe coupled to said thermoelectric cooling module wherein heat is transferred from said heat pipe to the cold surface of said cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from a tissue treatment site to said heat pipe; d) a heat exchanging means coupled to the hot surface of said cooling module for transferring heat from said cooling module to said heat exchanging means and into the ambient air; e) a control means connected to said thermoelectric cooling module for regulating the rate of heat transferred by said cooling module; and f) a sensing means connected to said control means for detecting the heat loss transferred from said treatment site to said electronic cryoprobe, wherein said sensing means relays temperature information to said control means, and wherein said control means processes said information to generate a multiple freeze-thaw cycle to be delivered by said electronic cryoprobe to said treatment site.
Claim 14
Dependent Claim
53 words
The electronic cryoprobe of claim 11 wherein said multiple freeze-thaw cycle is generated by the control means selectively increasing, and then selectively decreasing the voltage from said electric power means to said thermoelectric cooling module and wherein said selective increasing and decreasing in voltage is continued until the tissue being treated is destroyed.
Claim 15
Dependent Claim
76 words
The electronic cryoprobe of claim 11 wherein said multiple freeze-thaw cycle is generated by the control means selectively delivering constant voltage from said electric power means to said thermoelectric cooling module, causing the tissue to be cooled, followed by the said control means reversing the polarity of the voltage delivered to said thermoelectric module, causing the tissue to be warmed, and wherein said cycling in voltage polarity is continued until the tissue being treated is destroyed.
Claim 16
Dependent Claim
19 words
The electronic cryoprobe of claim 11 wherein said sensing means is coupled to the application tip of said cryoprobe.
Claim 17
Dependent Claim
18 words
The electronic cryoprobe of claim 11 wherein said sensing means is placed within the tissue subject to treatment.
Claim 18
Dependent Claim
21 words
The electronic cryoprobe of claim 15 wherein said sensing means consists of hypodermic thermocouple capable of being imbedded in said tissue.
Claim 19
Dependent Claim
21 words
The electronic cryoprobe of claim 11 wherein said heat pipe is capable of being detachably coupled to said thermoelectric cooling module.
Claim 20
Dependent Claim
20 words
The electronic cryoprobe of claim 11 wherein said application tip is capable of being detachably fitted to said heat pipe.
Claim 21
Dependent Claim
34 words
The electronic cryoprobe of claim 11 wherein said thermoelectric cooling module is capable of generating sustained temperatures of at least -55° C. by transferring heat from said cooling module to said heat exchanging means.
Claim 22
Dependent Claim
81 words
An electronic cryoprobe for treating tissue comprising: a) a first thermoelectric cooling module; b) a heat pipe coupled to said first thermoelectric cooling module wherein heat is transferred from said heat pipe to said first cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from said tissue site to said heat pipe; and d) a second thermoelectric cooling module coupled to said application tip wherein heat is transferred from said tip to said heat pipe.
Claim 23
Dependent Claim
81 words
An electronic cryoprobe for treating tissue comprising: a) a first thermoelectric cooling module; b) a heat pipe coupled to said first thermoelectric cooling module wherein heat is transferred from said heat pipe to said first cooling module; c) an application tip coupled to said heat pipe wherein heat is transferred from said tissue site to said heat pipe; and d) a second thermoelectric cooling module coupled to said application tip wherein heat is transferred from said tip to said heat pipe.
Claim 24
Dependent Claim
29 words
The electronic cryoprobe of claim 20 further comprising a control means connected to said first thermoelectric cooling module for regulating the rate of heat transferred by said cooling module.
Claim 25
Dependent Claim
66 words
The electronic cryoprobe of claim 21 further comprising a sensing means connected to said control means for detecting the heat loss transferred from said treatment site to said electronic cryoprobe, wherein said sensing means relays temperature information to said control means, and wherein said control means processes said information to generate a multiple freeze-thaw cycle to be delivered by said electronic cryoprobe to said treatment site.
Claim 26
Dependent Claim
54 words
The electronic cryoprobe of claim 22 wherein said multiple freeze-thaw cycle is generated by the said control means selectively increasing, and then selectively decreasing the voltage from said electric power means to said thermoelectric cooling module and wherein said selective increasing and decreasing in voltage is continued until the tissue being treated is destroyed.
Claim 27
Dependent Claim
77 words
The electronic cryoprobe of claim 22 wherein said multiple freeze-thaw cycle is generated by the said control means electively delivering constant voltage from said electric power means to said thermoelectric cooling module, causing the tissue to be cooled, followed by the said control means reversing the polarity of the voltage delivered to said thermoelectric module, causing the tissue to be warmed, and wherein said cycling in voltage polarity is continued until the tissue being treated is destroyed.
Claim 28
Dependent Claim
19 words
The electronic cryoprobe of claim 22 wherein said sensing means is coupled to the application tip of said cryoprobe.
Claim 29
Dependent Claim
18 words
The electronic cryoprobe of claim 22 wherein said sensing means is placed within the tissue subject to treatment.
Claim 30
Dependent Claim
21 words
The electronic cryoprobe of claim 26 wherein said sensing means consists of hypodermic thermocouple capable of being imbedded in said tissue.
Claim 31
Dependent Claim
21 words
The electronic cryoprobe of claim 20 wherein said heat pipe is capable of being detachably coupled to said thermoelectric cooling module.
Claim 32
Dependent Claim
20 words
The electronic cryoprobe of claim 20 wherein said application tip is capable of being detachably fitted to said heat pipe.
Claim 33
Dependent Claim
34 words
The electronic cryoprobe of claim 20 wherein said thermoelectric cooling module is capable of generating sustained temperatures of at least -55° C. by transferring heat from said cooling module to said heat exchanging means.
Claim 34
Independent Claim
59 words
A method of destroying and thereby treating benign and malignant tumors of the skin and mucous membranes comprising the steps of: a) transferring heat from a tissue treatment site to form a frozen bolus; b) monitoring said heat loss; and c) administering a freeze-thaw cycle to said tissue treatment site while maintaining a frozen outer wall of said bolus.
Claim 35
Independent Claim
59 words
A method of destroying and thereby treating benign and malignant tumors of the skin and mucous membranes comprising the steps of: a) transferring heat from a tissue treatment site to form a frozen bolus; b) monitoring said heat loss; and c) administering a freeze-thaw cycle to said tissue treatment site while maintaining a frozen outer wall of said bolus.
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USPTO Annuity & Maintenance Windows
| Annuity Stage | Window Opens | Payment Deadline | Surcharge Period Until | Estimated Fee | Status |
|---|---|---|---|---|---|
| 3.5 Years (Year 4) | 1996-05-03 | 1996-11-02 | 1997-05-04 | $2000.00 | Window Closed / Lapsed |
| 7.5 Years (Year 8) | 2000-05-03 | 2000-11-02 | 2001-05-04 | $3760.00 | Window Closed / Lapsed |
| 11.5 Years (Year 12) | 2004-05-03 | 2004-11-02 | 2005-05-04 | $7700.00 | Window Closed / Lapsed |